Product References
Germline Neurofibromin 1 mutation enhances the anti-tumour immune response and decreases juvenile myelomonocytic leukaemia tumourigenicity.
British journal of haematology
Wang W,Li X,Qin X,Miao Y,Zhang Y,Li S,Yao R,Yang Y,Yu L,Zhu H,Song L,Mao S,Wang X,Chen J,Feng H,Li Y
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Sat Jul 01 00:00:00 EDT 2023
Saharan dust induces NLRP3-dependent inflammatory cytokines in an alveolar air-liquid interface co-culture model.
Particle and fibre toxicology
Bredeck G,Dobner J,Stahlmecke B,Fomba KW,Herrmann H,Rossi A,Schins RPF
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Fri Oct 20 00:00:00 EDT 2023
miR-148a-3p and DDX6 functional link promotes survival of myeloid leukemia cells.
Blood advances
Ghashghaei M,Le CT,Shaalan H,Escano L,Yue M,Arsalan A,Rouhi A,Nguyen TA,Vu LP
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Tue Aug 08 00:00:00 EDT 2023
LAL deficiency induced myeloid-derived suppressor cells as targets and biomarkers for lung cancer.
Journal for immunotherapy of cancer
Zhao T,Liu S,Hanna NH,Jalal S,Ding X,Wan J,Yan C,Du H
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
Tumor suppressor p53 mediates interleukin-6 expression to enable cancer cell evasion of genotoxic stress.
Cell death discovery
Phan TTT,Truong NV,Wu WG,Su YC,Hsu TS,Lin LY
12-0149-42 was used in Flow cytometry/Cell sorting to reveal the precise mechanism for genotoxic-induced IL-6 and suggests that targeting p53-mediated IL-6 may improve the responsiveness of cancer cells to genotoxic anticancer therapy.
Mon Sep 11 00:00:00 EDT 2023
Spontaneous Osteoclastogenesis, a risk factor for bone metastasis in advanced luminal A-type breast cancer patients.
Frontiers in oncology
Fernández Vallone V,Borzone FR,Martinez LM,Giorello MB,Choi H,Dimase F,Feldman L,Bordenave RH,Chudzinski-Tavassi AM,Batagelj E,Chasseing NA
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Fri Mar 10 00:00:00 EST 2023
Plasma‑derived CD16 exosomes and peripheral blood monocytes as correlating biomarkers in head and neck cancer.
Oncology letters
Theodoraki MN,Hofmann L,Huber D,Brunner C,Hoffmann TK,Idel C,Fleckner J,Bruchhage KL,Pries R
12-0149-42 was used in Flow cytometry/Cell sorting to isolate exosomes from plasma samples of healthy donors and patients with HNSCC and evaluate their morphology, size and protein composition using transmission electron microscopy, western blotting and bead-based flow cytometry.
Mon May 01 00:00:00 EDT 2023
SARS-CoV-2 Delta (B.1.617.2) variant replicates and induces syncytia formation in human induced pluripotent stem cell-derived macrophages.
PeerJ
Thaweerattanasinp T,Wanitchang A,Saenboonrueng J,Srisutthisamphan K,Wanasen N,Sungsuwan S,Jongkaewwattana A,Chailangkarn T
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Thu Mar 09 00:00:00 EST 2023
Heliangin acts as a covalent ligand of RPS2 that disrupts pre-rRNA metabolic processes in NPM1-mutated acute myeloid leukemia.
Acta pharmaceutica Sinica. B
Feng Y,Han Y,Hu A,Qu Y,Hu Y,Wu H,Wang X,He L
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2023
A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
Journal of medicinal chemistry
Marín-Rubio JL,Peltier-Heap RE,Dueñas ME,Heunis T,Dannoura A,Inns J,Scott J,Simpson AJ,Blair HJ,Heidenreich O,Allan JM,Watt JE,Martin MP,Saxty B,Trost M
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Thu Sep 22 00:00:00 EDT 2022
Decoding the pathogenesis of Diamond-Blackfan anemia using single-cell RNA-seq.
Cell discovery
Wang B,Wang C,Wan Y,Gao J,Ma Y,Zhang Y,Tong J,Zhang Y,Liu J,Chang L,Xu C,Shen B,Chen Y,Jiang E,Kurita R,Nakamura Y,Lim KC,Engel JD,Zhou J,Cheng T,Zhu X,Zhu P,Shi L
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Tue May 10 00:00:00 EDT 2022
CDKN1A is a target for phagocytosis-mediated cellular immunotherapy in acute leukemia.
Nature communications
Allouch A,Voisin L,Zhang Y,Raza SQ,Lecluse Y,Calvo J,Selimoglu-Buet D,de Botton S,Louache F,Pflumio F,Solary E,Perfettini JL
12-0149-42 was used in Flow cytometry/Cell sorting to reveal p21 as a trigger of phagocytosis-guided pro-inflammatory TAM reprogramming and highlight the potential for p21TD-Mo-based cellular therapy as a cancer immunotherapy.
Tue Nov 08 00:00:00 EST 2022
The Composition of Adipose-Derived Regenerative Cells Isolated from Lipoaspirate Using a Point of Care System Does Not Depend on the Subject's Individual Age, Sex, Body Mass Index and Ethnicity.
Cells
Schmitz C,Alt C,Azares AR,Pearce DA,Facile TR,Furia JP,Maffulli N,Huang C,Alt EU
12-0149-42 was used in Flow cytometry/Cell sorting to show that key characteristics of unmodified, autologous, adipose-derived regenerative cells (UA-ADRCs) can be independent of the subject's age, sex, BMI and ethnicity.
Wed Dec 21 00:00:00 EST 2022
Mycobacterium leprae induces a tolerogenic profile in monocyte-derived dendritic cells via TLR2 induction of IDO.
Journal of leukocyte biology
Oliveira JAP,Gandini M,Sales JS,Fujimori SK,Barbosa MGM,Frutuoso VS,Moraes MO,Sarno EN,Pessolani MCV,Pinheiro RO
12-0149-42 was used in Flow Cytometry to investigate the mechanisms associated with IDO-1 expression and activity in human monocyte-derived dendritic cells (mDCs) after stimulation with irradiated Mycobacterium leprae and its fractions.
Thu Jul 01 00:00:00 EDT 2021
Human induced pluripotent stem cell-derived macrophages ameliorate liver fibrosis.
Stem cells (Dayton, Ohio)
Pouyanfard S,Meshgin N,Cruz LS,Diggle K,Hashemi H,Pham TV,Fierro M,Tamayo P,Fanjul A,Kisseleva T,Kaufman DS
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Wed Dec 01 00:00:00 EST 2021
SARS-CoV-2 infection paralyzes cytotoxic and metabolic functions of the immune cells.
Heliyon
Singh Y,Trautwein C,Fendel R,Krickeberg N,Berezhnoy G,Bissinger R,Ossowski S,Salker MS,Casadei N,Riess O
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Tue Jun 01 00:00:00 EDT 2021
Exposure of a specific pleioform of multifunctional glyceraldehyde 3-phosphate dehydrogenase initiates CD14-dependent clearance of apoptotic cells.
Cell death & disease
Chaudhary S,Patidar A,Dhiman A,Chaubey GK,Dilawari R,Talukdar S,Modanwal R,Raje M
12-0149-42 was used in Flow cytometry/Cell sorting to demonstrate the novel interaction between multifunctional GAPDH and the phagocytic receptor CD14 resulting in apoptotic cell clearance (efferocytosis).
Thu Sep 30 00:00:00 EDT 2021
Exposure of a specific pleioform of multifunctional glyceraldehyde 3-phosphate dehydrogenase initiates CD14-dependent clearance of apoptotic cells.
Cell death & disease
Chaudhary S,Patidar A,Dhiman A,Chaubey GK,Dilawari R,Talukdar S,Modanwal R,Raje M
12-0149-42 was used in Flow cytometry/Cell sorting to demonstrate the novel interaction between multifunctional GAPDH and the phagocytic receptor CD14 resulting in apoptotic cell clearance (efferocytosis).
Thu Sep 30 00:00:00 EDT 2021
SUGT1 controls susceptibility to HIV-1 infection by stabilizing microtubule plus-ends.
Cell death and differentiation
Allouch A,Di Primio C,Paoletti A,Lê-Bury G,Subra F,Quercioli V,Nardacci R,David A,Saïdi H,Cereseto A,Ojcius DM,Montagnac G,Niedergang F,Pancino G,Saez-Cirion A,Piacentini M,Gougeon ML,Kroemer G,Perfettini JL
12-0149-42 was used in Flow Cytometry to identify SUGT1 as a cellular factor involved in the post-entry steps of HIV-1 infection that may be targeted for new therapeutic approaches.
Tue Dec 01 00:00:00 EST 2020
The long non-coding RNA Cancer Susceptibility 15 (CASC15) is induced by isocitrate dehydrogenase (IDH) mutations and maintains an immature phenotype in adult acute myeloid leukemia.
Haematologica
Grasedieck S,Ruess C,Krowiorz K,Lux S,Pochert N,Schwarzer A,Klusmann JH,Jongen-Lavrencic M,Herold T,Bullinger L,Pollack JR,Rouhi A,Kuchenbauer F
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2020
Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruzi strains unveil a role for fibroblasts in neutrophil recruitment and activation.
PLoS pathogens
Oliveira AER,Pereira MCA,Belew AT,Ferreira LRP,Pereira LMN,Neves EGA,Nunes MDCP,Burleigh BA,Dutra WO,El-Sayed NM,Gazzinelli RT,Teixeira SMR
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2020
A functional antibody cross-reactive to both human and murine cytotoxic T-lymphocyte-associated protein 4 via binding to an N-glycosylation epitope.
mAbs
Li D,Li J,Chu H,Wang Z
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Fri Feb 12 00:00:00 EST 2021
Differentiation Potential of Early- and Late-Passage Adipose-Derived Mesenchymal Stem Cells Cultured under Hypoxia and Normoxia.
Stem cells international
Zhao AG,Shah K,Freitag J,Cromer B,Sumer H
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Tue Oct 06 00:00:00 EDT 2020
MiR-103 protects from recurrent spontaneous abortion via inhibiting STAT1 mediated M1 macrophage polarization.
International journal of biological sciences
Zhu X,Liu H,Zhang Z,Wei R,Zhou X,Wang Z,Zhao L,Guo Q,Zhang Y,Chu C,Wang L,Li X
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Fri Nov 12 00:00:00 EST 2021
Patient iPSC-Derived Macrophages to Study Inborn Errors of the IFN-γ Responsive Pathway.
Cells
Haake K,Neehus AL,Buchegger T,Kühnel MP,Blank P,Philipp F,Oleaga-Quintas C,Schulz A,Grimley M,Goethe R,Jonigk D,Kalinke U,Boisson-Dupuis S,Casanova JL,Bustamante J,Lachmann N
12-0149 was used in Flow cytometry/Cell sorting to report a disease modeling platform to study the role of macrophages in patients with inborn errors of IFN-γ immunity.
Wed Feb 19 00:00:00 EST 2020
Patient iPSC-Derived Macrophages to Study Inborn Errors of the IFN-γ Responsive Pathway.
Cells
Haake K,Neehus AL,Buchegger T,Kühnel MP,Blank P,Philipp F,Oleaga-Quintas C,Schulz A,Grimley M,Goethe R,Jonigk D,Kalinke U,Boisson-Dupuis S,Casanova JL,Bustamante J,Lachmann N
12-0149 was used in Flow cytometry/Cell sorting to report a disease modeling platform to study the role of macrophages in patients with inborn errors of IFN-γ immunity.
Wed Feb 19 00:00:00 EST 2020
Chemerin enhances the adhesion and migration of human endothelial progenitor cells and increases lipid accumulation in mice with atherosclerosis.
Lipids in health and disease
Jia J,Yu F,Xiong Y,Wei W,Ma H,Nisi F,Song X,Yang L,Wang D,Yuan G,Zhou H
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Sun Sep 20 00:00:00 EDT 2020
LILRB3 (ILT5) is a myeloid cell checkpoint that elicits profound immunomodulation.
JCI insight
Yeboah M,Papagregoriou C,Jones DC,Chan HTC,Hu G,McPartlan JS,Schiött T,Mattson U,Mockridge CI,Tornberg UC,Hambe B,Ljungars A,Mattsson M,Tews I,Glennie MJ,Thirdborough SM,Trowsdale J,Frendeus B,Chen J,Cragg MS,Roghanian A
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2020
LILRB3 (ILT5) is a myeloid cell checkpoint that elicits profound immunomodulation.
JCI insight
Yeboah M,Papagregoriou C,Jones DC,Chan HTC,Hu G,McPartlan JS,Schiött T,Mattson U,Mockridge CI,Tornberg UC,Hambe B,Ljungars A,Mattsson M,Tews I,Glennie MJ,Thirdborough SM,Trowsdale J,Frendeus B,Chen J,Cragg MS,Roghanian A
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2020
LILRB3 (ILT5) is a myeloid cell checkpoint that elicits profound immunomodulation.
JCI insight
Yeboah M,Papagregoriou C,Jones DC,Chan HTC,Hu G,McPartlan JS,Schiött T,Mattson U,Mockridge CI,Tornberg UC,Hambe B,Ljungars A,Mattsson M,Tews I,Glennie MJ,Thirdborough SM,Trowsdale J,Frendeus B,Chen J,Cragg MS,Roghanian A
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2020
NLRP3 Inflammasome Activation in Hemodialysis and Hypertensive Patients with Intact Kidney Function.
Toxins
Ulrich C,Wildgrube S,Fiedler R,Seibert E,Kneser L,Fick S,Schäfer C,Markau S,Trojanowicz B,Girndt M
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Mon Oct 26 00:00:00 EDT 2020
Cross-talk between microglia and neurons regulates HIV latency.
PLoS pathogens
Alvarez-Carbonell D,Ye F,Ramanath N,Garcia-Mesa Y,Knapp PE,Hauser KF,Karn J
12-0149 was used in Flow cytometry/Cell sorting to demonstrate that the cross-talk between healthy neurons and microglia modulates HIV expression, while HIV expression impairs this intrinsic molecular mechanism resulting in the excessive and uncontrolled stimulation of microglia-mediated neurotoxicity.
Sun Dec 01 00:00:00 EST 2019
NLRP3 inflammasome expression in peripheral blood monocytes of coronary heart disease patients and its modulation by rosuvastatin.
Molecular medicine reports
Zhu J,Wu S,Hu S,Li H,Li M,Geng X,Wang H
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Thu Aug 01 00:00:00 EDT 2019
Investigating the potential of the secretome of mesenchymal stem cells derived from sickle cell disease patients.
PloS one
Ribeiro TO,Silveira BM,Meira MC,Carreira ACO,Sogayar MC,Meyer R,Fortuna V
12-0149 was used in Flow cytometry/Cell sorting to find that hypoxically conditioned cells presented increased expression and secretion of several well-characterized trophic growth factors (VEGF, IL8, MCP-1, ANG) directly linked to angiogenesis and tissue repair.
Wed Mar 11 00:00:00 EDT 2020
Si-ni-tang (a Chinese herbal formula) for improving immunofunction in sepsis: study protocol for a pilot randomized controlled trial.
Trials
Zeng R,Zheng Y,Fan R,Zhou G,Zhang Y,Mai S,Xie D,Weng Y,Du J,Han Y,Lai F
12-0149 was used in Flow cytometry/Cell sorting to study whether a Chinese herbal treatment, Si-ni-tang, can improve immunofunction in sepsis patients.
Wed Aug 28 00:00:00 EDT 2019
Characterizing the Role of Monocytes in T Cell Cancer Immunotherapy Using a 3D Microfluidic Model.
Frontiers in immunology
Lee SWL,Adriani G,Ceccarello E,Pavesi A,Tan AT,Bertoletti A,Kamm RD,Wong SC
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Mon Jun 24 00:00:00 EDT 2019
Long Non-Coding RNA HOXA Transcript Antisense RNA Myeloid-Specific 1-HOXA1 Axis Downregulates the Immunosuppressive Activity of Myeloid-Derived Suppressor Cells in Lung Cancer.
Frontiers in immunology
Tian X,Ma J,Wang T,Tian J,Zhang Y,Mao L,Xu H,Wang S
12-0149 was used in Flow cytometry/Cell sorting to conclude that HOXA transcript antisense RNA myeloid-specific 1 (HOTAIRM1) downregulates the immunosuppressive function of myeloid-derived suppressor cells by targeting HOXA1, providing a potential therapeutic target in lung cancer.
Mon Jun 24 00:00:00 EDT 2019
Role of enterocyte stearoyl-Co-A desaturase-1 in LDLR-null mice.
Journal of lipid research
Mukherjee P,Hough G,Chattopadhyay A,Grijalva V,O'Connor EI,Meriwether D,Wagner A,Ntambi JM,Navab M,Reddy ST,Fogelman AM
12-0149 was used in an ELISA assay to conclude that enterocyte Scd1 is partially responsible for LysoPC 18:1- and WD-induced dyslipidemia and inflammation in ldlr-/- mice.
Mon Oct 01 00:00:00 EDT 2018
AURKA Suppresses Leukemic THP-1 Cell Differentiation through Inhibition of the KDM6B Pathway.
Molecules and cells
Park JW,Cho H,Oh H,Kim JY,Seo SB
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Thu May 31 00:00:00 EDT 2018
Butyrate upregulates the TLR4 expression and the phosphorylation of MAPKs and NK-κB in colon cancer cell in vitro.
Oncology letters
Xiao T,Wu S,Yan C,Zhao C,Jin H,Yan N,Xu J,Wu Y,Li C,Shao Q,Xia S
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2018
Impaired efferocytosis by monocytes in multiple myeloma.
Oncology letters
Liang YY,Schwarzinger I,Simonitsch-Klupp I,Agis H,Oehler R
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Sun Jul 01 00:00:00 EDT 2018
Human umbilical cord-derived mesenchymal stem cells ameliorate the enteropathy of food allergies in mice.
Experimental and therapeutic medicine
Yan N,Xu J,Zhao C,Wu Y,Gao F,Li C,Zhou W,Xiao T,Zhou X,Shao Q,Xia S
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2018
Comprehensive characterization of chorionic villi-derived mesenchymal stromal cells from human placenta.
Stem cell research & therapy
Ventura Ferreira MS,Bienert M,Müller K,Rath B,Goecke T,Opländer C,Braunschweig T,Mela P,Brümmendorf TH,Beier F,Neuss S
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Mon Feb 05 00:00:00 EST 2018
Cellular metabolism constrains innate immune responses in early human ontogeny.
Nature communications
Kan B,Michalski C,Fu H,Au HHT,Lee K,Marchant EA,Cheng MF,Anderson-Baucum E,Aharoni-Simon M,Tilley P,Mirmira RG,Ross CJ,Luciani DS,Jan E,Lavoie PM
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Fri Nov 16 00:00:00 EST 2018
The pro-inflammatory phenotype of the human non-classical monocyte subset is attributed to senescence.
Cell death & disease
Ong SM,Hadadi E,Dang TM,Yeap WH,Tan CT,Ng TP,Larbi A,Wong SC
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Thu Feb 15 00:00:00 EST 2018
Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes.
eLife
Lin JR,Izar B,Wang S,Yapp C,Mei S,Shah PM,Santagata S,Sorger PK
12-0149-42 was used in Flow Cytometry to develop a tissue-based cyclic immunofluorescence method for highly multiplexed immuno-fluorescence imaging of formalin-fixed, paraffin-embedded specimens mounted on glass slides.
Wed Jul 11 00:00:00 EDT 2018
IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells.
Nature communications
Hsieh WC,Hsu TS,Chang YJ,Lai MZ
12-0149 was used in Flow cytometry/Cell sorting to demonstrate that immunosuppressive defects in XIAP-deficient regulatory T cells can be corrected by treatment with autologous induced Treg cells and IL-6 Receptor blockade.
Wed Jan 31 00:00:00 EST 2018
IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells.
Nature communications
Hsieh WC,Hsu TS,Chang YJ,Lai MZ
12-0149 was used in Flow cytometry/Cell sorting to demonstrate that immunosuppressive defects in XIAP-deficient regulatory T cells can be corrected by treatment with autologous induced Treg cells and IL-6 Receptor blockade.
Wed Jan 31 00:00:00 EST 2018
The Synergistic Effects of the Glutathione Precursor, NAC and First-Line Antibiotics in the Granulomatous Response Against Mycobacterium tuberculosis.
Frontiers in immunology
Teskey G,Cao R,Islamoglu H,Medina A,Prasad C,Prasad R,Sathananthan A,Fraix M,Subbian S,Zhong L,Venketaraman V
12-0149 was used in Immunocytochemistry-immunoflourescence to examine if N-Acetyl Cysteine in combination with antibiotics would be sufficient to completely clear Mycobacterium tuberculosis infection within in vitro granulomas.
Mon Sep 30 00:00:00 EDT 2019
Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections.
Nature communications
Ackermann M,Kempf H,Hetzel M,Hesse C,Hashtchin AR,Brinkert K,Schott JW,Haake K,Kühnel MP,Glage S,Figueiredo C,Jonigk D,Sewald K,Schambach A,Wronski S,Moritz T,Martin U,Zweigerdt R,Munder A,Lachmann N
12-0149 was used in Flow cytometry/Cell sorting to develop a novel, cell-based treatment strategy to target bacterial airway infections.
Fri Nov 30 00:00:00 EST 2018
Blocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer.
Cell research
Su S,Liao J,Liu J,Huang D,He C,Chen F,Yang L,Wu W,Chen J,Lin L,Zeng Y,Ouyang N,Cui X,Yao H,Su F,Huang JD,Lieberman J,Liu Q,Song E
12-0149 was used in Flow cytometry/Cell sorting to demonstrate that blocking PITPNM3 recognition of CCL18 could be an attractive immunotherapy aproach for treating breast cancer.
Sat Apr 01 00:00:00 EDT 2017
A therapeutic T cell receptor mimic antibody targets tumor-associated PRAME peptide/HLA-I antigens.
The Journal of clinical investigation
Chang AY,Dao T,Gejman RS,Jarvis CA,Scott A,Dubrovsky L,Mathias MD,Korontsvit T,Zakhaleva V,Curcio M,Hendrickson RC,Liu C,Scheinberg DA
12-0149 was used in Flow cytometry/Cell sorting to investigate the effect of Pr20 on cancer.
Fri Jun 30 00:00:00 EDT 2017
Global survey of the immunomodulatory potential of common drugs.
Nature chemical biology
Vladimer GI,Snijder B,Krall N,Bigenzahn JW,Huber KVM,Lardeau CH,Sanjiv K,Ringler A,Berglund UW,Sabler M,de la Fuente OL,Knöbl P,Kubicek S,Helleday T,Jäger U,Superti-Furga G
12-0149 was used in Flow cytometry/Cell sorting to offer an attractive platform for the personalized identification and characterization of immunomodulatory therapeutics.
Thu Jun 01 00:00:00 EDT 2017
Bacillus anthracis lethal toxin negatively modulates ILC3 function through perturbation of IL-23-mediated MAPK signaling.
PLoS pathogens
Seshadri S,Allan DSJ,Carlyle JR,Zenewicz LA
12-0149 was used in Flow cytometry/Cell sorting to study the effects of MAPK signalling pathways in group 3 innate immune lymphocytes using Bacillus anthracis.
Sun Oct 01 00:00:00 EDT 2017
The Influence of Cytomegalovirus on Expression of HLA-G and its Ligand KIR2DL4 by Human Peripheral Blood Leucocyte Subsets.
Scandinavian journal of immunology
Albayati Z,Alyami A,Alomar S,Middleton D,Bonnett L,Aleem S,Flanagan BF,Christmas SE
12-0149-42 was used in Flow cytometry/Cell sorting to show that CMV influences HLA-G expression in healthy subjects and may contribute to viral immune evasion.
Wed Nov 01 00:00:00 EDT 2017
Human umbilical cord mesenchymal stem cells improve the reserve function of perimenopausal ovary via a paracrine mechanism.
Stem cell research & therapy
Li J,Mao Q,He J,She H,Zhang Z,Yin C
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Thu Mar 09 00:00:00 EST 2017
Effects of acute exposure to low-dose radiation on the characteristics of human bone marrow mesenchymal stromal/stem cells.
Inflammation and regeneration
Fujishiro A,Miura Y,Iwasa M,Fujii S,Sugino N,Andoh A,Hirai H,Maekawa T,Ichinohe T
12-0149 was used in Flow cytometry/Cell sorting to determine whether low dose irradiation affects the function of mesenchymal stromal/stem cells.
Fri Mar 11 00:00:00 EST 2022
Systemic T Cells Immunosuppression of Glioma Stem Cell-Derived Exosomes Is Mediated by Monocytic Myeloid-Derived Suppressor Cells.
PloS one
Domenis R,Cesselli D,Toffoletto B,Bourkoula E,Caponnetto F,Manini I,Beltrami AP,Ius T,Skrap M,Di Loreto C,Gri G
12-0149 was used in Flow cytometry/Cell sorting to investigate the immunomodulatory properties of GCS-derived exosomes on different peripheral immune cell populations.
Thu Aug 10 00:00:00 EDT 2017
Pulmonary sarcoidosis is associated with high-level inducible co-stimulator (ICOS) expression on lung regulatory T cells--possible implications for the ICOS/ICOS-ligand axis in disease course and resolution.
Clinical and experimental immunology
Sakthivel P,Grunewald J,Eklund A,Bruder D,Wahlström J
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2016
Antithymocyte Globulin at Clinically Relevant Concentrations Kills Leukemic Blasts.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
Dabas R,Lee R,Servito MT,Dharmani-Khan P,Modi M,van Slyke T,Luider J,Durand C,Larratt L,Brandwein J,Morris D,Daly A,Khan FM,Storek J
Sun May 01 00:00:00 EDT 2016
Microfluidic device for simultaneous analysis of neutrophil extracellular traps and production of reactive oxygen species.
Integrative biology : quantitative biosciences from nano to macro
Moussavi-Harami SF,Mladinich KM,Sackmann EK,Shelef MA,Starnes TW,Guckenberger DJ,Huttenlocher A,Beebe DJ
12-0149 was used in Immunohistochemistry-immunofluorescence to develop a microfluidic device to quantify both reactive oxygen species and neutrophil extracellular trap production over time in response to various stimulants, including live bacteria.
Mon Feb 01 00:00:00 EST 2016
Thrombomodulin regulates monocye differentiation via PKCδ and ERK1/2 pathway in vitro and in atherosclerotic artery.
Scientific reports
Tsai CS,Lin YW,Huang CY,Shih CM,Tsai YT,Tsao NW,Lin CS,Shih CC,Jeng H,Lin FY
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Fri Dec 02 00:00:00 EST 2016
STK4 regulates TLR pathways and protects against chronic inflammation-related hepatocellular carcinoma.
The Journal of clinical investigation
Li W,Xiao J,Zhou X,Xu M,Hu C,Xu X,Lu Y,Liu C,Xue S,Nie L,Zhang H,Li Z,Zhang Y,Ji F,Hui L,Tao W,Wei B,Wang H
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Mon Nov 02 00:00:00 EST 2015
Antibodies to P-selectin glycoprotein ligand-1 block dendritic cell-mediated enterovirus 71 transmission and prevent virus-induced cells death.
Virulence
Ren XX,Li C,Xiong SD,Huang Z,Wang JH,Wang HB
12-0149 was used in Flow cytometry/Cell sorting to demonstrate that PSGL-1 present on the cell surfaces of monocyte-derived dendritic cells mediates enterovirus 71 binding and facilitates further infection.
Thu Oct 06 00:00:00 EDT 2016
HIV-1-triggered release of type I IFN by plasmacytoid dendritic cells induces BAFF production in monocytes.
Journal of immunology (Baltimore, Md. : 1950)
Gomez AM,Ouellet M,Tremblay MJ
12-0149 was used in Flow cytometry/Cell sorting to assess the effect of HIV-1 (X4- and R5-tropic) on BAFF expression and secretion by human monocytes.
Sun Mar 01 00:00:00 EST 2015
Liposomal Glutathione Supplementation Restores TH1 Cytokine Response to Mycobacterium tuberculosis Infection in HIV-Infected Individuals.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Ly J,Lagman M,Saing T,Singh MK,Tudela EV,Morris D,Anderson J,Daliva J,Ochoa C,Patel N,Pearce D,Venketaraman V
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2015
Investigating the causes for decreased levels of glutathione in individuals with type II diabetes.
PloS one
Lagman M,Ly J,Saing T,Kaur Singh M,Vera Tudela E,Morris D,Chi PT,Ochoa C,Sathananthan A,Venketaraman V
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Wed Dec 30 00:00:00 EST 2015
A novel antibody-drug conjugate targeting SAIL for the treatment of hematologic malignancies.
Blood cancer journal
Kim SY,Theunissen JW,Balibalos J,Liao-Chan S,Babcock MC,Wong T,Cairns B,Gonzalez D,van der Horst EH,Perez M,Levashova Z,Chinn L,D'Alessio JA,Flory M,Bermudez A,Jackson DY,Ha E,Monteon J,Bruhns MF,Chen G,Migone TS
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Fri May 29 00:00:00 EDT 2015
Immune cell subsets and their gene expression profiles from human PBMC isolated by Vacutainer Cell Preparation Tube (CPT™) and standard density gradient.
BMC immunology
Corkum CP,Ings DP,Burgess C,Karwowska S,Kroll W,Michalak TI
12-0149 was used in Flow cytometry/Cell sorting to assess and compare the ability of two isolation protocols to purify high quality immune cell subpopulations.
Wed Aug 26 00:00:00 EDT 2015
Efficacy of autologous stem cell-based therapy for osteonecrosis of the femoral head in sickle cell disease: a five-year follow-up study.
Stem cell research & therapy
Daltro GC,Fortuna V,de Souza ES,Salles MM,Carreira AC,Meyer R,Freire SM,Borojevic R
12-0149 was used in Flow cytometry/Cell sorting to report a significant improvement in clinical joint symptoms and pain relief in patients after bone marrow-derived mononuclear cell implantation.
Fri May 29 00:00:00 EDT 2015
Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes.
Nature communications
Viganò E,Diamond CE,Spreafico R,Balachander A,Sobota RM,Mortellaro A
12-0149 was used in Flow cytometry/Cell sorting to investigate signalling pathways that regulate the pathology of endotoxin shock.
Wed Oct 28 00:00:00 EDT 2015
CX₃CR1⁺ mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22.
The Journal of experimental medicine
Longman RS,Diehl GE,Victorio DA,Huh JR,Galan C,Miraldi ER,Swaminath A,Bonneau R,Scherl EJ,Littman DR
12-0149 was used in Flow cytometry/Cell sorting to study the role of CX3CR1+ mononuclear phagocytes in the development of colitis and disease progression following Citrobacter rodentium infection.
Mon Jul 28 00:00:00 EDT 2014
Mast cell histamine promotes the immunoregulatory activity of myeloid-derived suppressor cells.
Journal of leukocyte biology
Martin RK,Saleem SJ,Folgosa L,Zellner HB,Damle SR,Nguyen GK,Ryan JJ,Bear HD,Irani AM,Conrad DH
12-0149 was used in Flow cytometry/Cell sorting to indicate that MCs and MC-released histamine are critical for MDSC-mediated immune regulation.
Tue Jul 01 00:00:00 EDT 2014
Human mesenchymal stem cells possess different biological characteristics but do not change their therapeutic potential when cultured in serum free medium.
Stem cell research & therapy
Wang Y,Wu H,Yang Z,Chi Y,Meng L,Mao A,Yan S,Hu S,Zhang J,Zhang Y,Yu W,Ma Y,Li T,Cheng Y,Wang Y,Wang S,Liu J,Han J,Li C,Liu L,Xu J,Han ZB,Han ZC
12-0149 was used in Flow cytometry/Cell sorting to investigate the biological and safety issues associated with culturing human mesenchymal stem cells in serum free medium.
Thu Dec 04 00:00:00 EST 2014
Biologically active polymers from spontaneous carotenoid oxidation: a new frontier in carotenoid activity.
PloS one
Johnston JB,Nickerson JG,Daroszewski J,Mogg TJ,Burton GW
12-0149 was used in Flow cytometry/Cell sorting to study carotenoid activity via biologically active polymers from spontaneous carotenoid oxidation.
Thu Jun 25 00:00:00 EDT 2015
Noncanonical dendritic cell differentiation and survival driven by a bacteremic pathogen.
Journal of leukocyte biology
Miles B,Scisci E,Carrion J,Sabino GJ,Genco CA,Cutler CW
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Thu Aug 01 00:00:00 EDT 2013
Induction of autophagy is essential for monocyte-macrophage differentiation.
Blood
Zhang Y,Morgan MJ,Chen K,Choksi S,Liu ZG
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Thu Mar 22 00:00:00 EDT 2012
Prednisolone exerts exquisite inhibitory properties on platelet functions.
Biochemical pharmacology
Liverani E,Banerjee S,Roberts W,Naseem KM,Perretti M
12-0149 was used in Flow cytometry/Cell sorting to investigate the effects of prednisolone on broader aspects of platelet functions, showing that it exerts exquisite inhibitory properties on platelet functions.
Tue May 15 00:00:00 EDT 2012
Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes.
Arthritis research & therapy
Sekine C,Koyanagi A,Koyama N,Hozumi K,Chiba S,Yagita H
12-0149 was used in Flow cytometry/Cell sorting to determine the role of individual Notch receptors and ligands in osteoclastogenesis..
Mon Mar 05 00:00:00 EST 2012
Negative regulation of JAK2 by H3K9 methyltransferase G9a in leukemia.
Molecular and cellular biology
Son HJ,Kim JY,Hahn Y,Seo SB
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2012
Human papillomavirus immunization is associated with increased expression of different innate immune regulatory receptors.
Clinical and vaccine immunology : CVI
Colmenares V,Noyola DE,Monsiváis-Urenda A,Salgado-Bustamante M,Estrada-Capetillo L,González-Amaro R,Baranda L
12-0149 was used in Flow cytometry/Cell sorting to study how HPV immunisation alters innate immune receptor function as part of its protective effect.
Sun Jul 01 00:00:00 EDT 2012
Vitamin D suppression of endoplasmic reticulum stress promotes an antiatherogenic monocyte/macrophage phenotype in type 2 diabetic patients.
The Journal of biological chemistry
Riek AE,Oh J,Sprague JE,Timpson A,de las Fuentes L,Bernal-Mizrachi L,Schechtman KB,Bernal-Mizrachi C
12-0149 was used in Flow cytometry/Cell sorting to investigate the the possible role of vitamin D deficiency as a mechanism of increased atherosclerosis in T2DM patients.
Fri Nov 09 00:00:00 EST 2012
Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients.
Critical care (London, England)
Zhang Y,Li J,Lou J,Zhou Y,Bo L,Zhu J,Zhu K,Wan X,Cai Z,Deng X
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Wed Dec 07 00:00:00 EST 2011
Diesel exhaust particles override natural injury-limiting pathways in the lung.
American journal of physiology. Lung cellular and molecular physiology
Chaudhuri N,Paiva C,Donaldson K,Duffin R,Parker LC,Sabroe I
12-0149 was used in Flow cytometry/Cell sorting to study a model of inflammation where diesel exhaust particles can alter the nature of the inflammatory milieu induced by TLR agonists.
Sun Aug 01 00:00:00 EDT 2010
Ro60-associated single-stranded RNA links inflammation with fetal cardiac fibrosis via ligation of TLRs: a novel pathway to autoimmune-associated heart block.
Journal of immunology (Baltimore, Md. : 1950)
Clancy RM,Alvarez D,Komissarova E,Barrat FJ,Swartz J,Buyon JP
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Mon Feb 15 00:00:00 EST 2010
Differential IL-7 responses in developing human thymocytes.
Human immunology
Marino JH,Tan C,Taylor AA,Bentley C,Van De Wiele CJ,Ranne R,Paliotta M,Broughan TA,Teague TK
12-0149 was used in Flow cytometry/Cell sorting to assess IL-7 receptor expression and IL-7 signalling in human thymocytes.
Thu Apr 01 00:00:00 EDT 2010
An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice.
The Journal of clinical investigation
Tieu BC,Lee C,Sun H,Lejeune W,Recinos A,Ju X,Spratt H,Guo DC,Milewicz D,Tilton RG,Brasier AR
12-0149 was used in Flow cytometry/Cell sorting to identify a vascular inflammatory pathway that contributes to the development of cardiovascular disease.
Tue Dec 01 00:00:00 EST 2009
Sepsis-induced human lymphocyte apoptosis and cytokine production in "humanized" mice.
Journal of leukocyte biology
Unsinger J,McDonough JS,Shultz LD,Ferguson TA,Hotchkiss RS
12-0149 was used in Flow cytometry/Cell sorting to develop a humanised mouse model that recapitulates many of the classic findings in patients with sepsis.
Sat Aug 01 00:00:00 EDT 2009
B cells and monocytes from patients with active multiple sclerosis exhibit increased surface expression of both HERV-H Env and HERV-W Env, accompanied by increased seroreactivity.
Retrovirology
Brudek T,Christensen T,Aagaard L,Petersen T,Hansen HJ,Møller-Larsen A
Published figure using CD14 monoclonal antibody (Product # 12-0149-42) in Flow Cytometry
Mon Nov 16 00:00:00 EST 2009
Immunological aspects of REIC/Dkk-3 in monocyte differentiation and tumor regression.
International journal of oncology
Watanabe M,Kashiwakura Y,Huang P,Ochiai K,Futami J,Li SA,Takaoka M,Nasu Y,Sakaguchi M,Huh NH,Kumon H
12-0149-42 was used in Flow cytometry/Cell sorting to study that recombinant REIC/Dkk-3 protein induced the differentiation of human CD14+ monocytes into a novel cell type.
Sun Mar 01 00:00:00 EST 2009
An antibody against the surfactant protein A (SP-A)-binding domain of the SP-A receptor inhibits T cell-mediated immune responses to Mycobacterium tuberculosis.
Journal of leukocyte biology
Samten B,Townsend JC,Sever-Chroneos Z,Pasquinelli V,Barnes PF,Chroneos ZC
12-0149 was used in Flow cytometry/Cell sorting to study the effect of antibodies on T cell immune responses against M.tuberculosis.
Tue Jul 01 00:00:00 EDT 2008
A phosphatidylserine species inhibits a range of TLR- but not IL-1beta-induced inflammatory responses by disruption of membrane microdomains.
Journal of immunology (Baltimore, Md. : 1950)
Parker LC,Prestwich EC,Ward JR,Smythe E,Berry A,Triantafilou M,Triantafilou K,Sabroe I
12-0149 was used in Flow cytometry/Cell sorting to investigate the ability of SAPS to inhibit the proinflammatory effects of TLR agonists in models of inflammation.
Wed Oct 15 00:00:00 EDT 2008
Enhanced efficacy of CTLA-4 fusion anti-caries DNA vaccines in gnotobiotic hamsters.
Acta pharmacologica Sinica
Zhang F,Li YH,Fan MW,Jia R,Xu QA,Guo JH,Yu F,Tian QW
12-0149 was used in Flow cytometry/Cell sorting to prove CTLLA-4-antigen fusion enhances anti-caries DNA vaccines.
Wed Aug 01 00:00:00 EDT 2007
Mycobacterium tuberculosis-induced gamma interferon production by natural killer cells requires cross talk with antigen-presenting cells involving Toll-like receptors 2 and 4 and the mannose receptor in tuberculous pleurisy.
Infection and immunity
Schierloh P,Yokobori N,Alemán M,Landoni V,Geffner L,Musella RM,Castagnino J,Baldini M,Abbate E,de la Barrera SS,Sasiain MC
12-0149 was used in Flow cytometry/Cell sorting to study how the interplay between M. tuberculosis and NK cells/APC triggering IFN-gamma may play a beneficial role in tuberculous pleurisy by helping to maintain a type 1 profile.
Thu Nov 01 00:00:00 EDT 2007
Membrane-anchored CD14 is important for induction of interleukin-8 by lipopolysaccharide and peptidoglycan in uroepithelial cells.
Clinical and diagnostic laboratory immunology
Shimizu T,Yokota S,Takahashi S,Kunishima Y,Takeyama K,Masumori N,Takahashi A,Matsukawa M,Itoh N,Tsukamoto T,Fujii N
12-0149 was used in Flow cytometry/Cell sorting to identify factors promoting IL-8 induction in bladder epithelial cells in response to bacterial components.
Wed Sep 01 00:00:00 EDT 2004
