Product References
L-DOS47 Elevates Pancreatic Cancer Tumor pH and Enhances Response to Immunotherapy.
Biomedicines
Jardim-Perassi BV,Irrera P,Oluwatola OE,Abrahams D,Estrella VC,Ordway B,Byrne SR,Ojeda AA,Whelan CJ,Kim J,Beatty MS,Damgaci-Erturk S,Longo DL,Gaspar KJ,Siegers GM,Centeno BA,Lau JYC,Pilon-Thomas SA,Ibrahim-Hashim A,Gillies RJ
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Mon Feb 19 00:00:00 UTC 2024
PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation.
Nature communications
Linnerbauer M,Beyer T,Nirschl L,Farrenkopf D,Lößlein L,Vandrey O,Peter A,Tsaktanis T,Kebir H,Laplaud D,Oellinger R,Engleitner T,Alvarez JI,Rad R,Korn T,Hemmer B,Quintana FJ,Rothhammer V
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Sat Sep 09 00:00:00 UTC 2023
PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation.
Nature communications
Linnerbauer M,Beyer T,Nirschl L,Farrenkopf D,Lößlein L,Vandrey O,Peter A,Tsaktanis T,Kebir H,Laplaud D,Oellinger R,Engleitner T,Alvarez JI,Rad R,Korn T,Hemmer B,Quintana FJ,Rothhammer V
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Sat Sep 09 00:00:00 UTC 2023
AR-A014418 regulates intronic polyadenylation and transcription of PD-L1 through inhibiting CDK12 and CDK13 in tumor cells.
Journal for immunotherapy of cancer
Zhang G,Lan B,Zhang X,Lin M,Liu Y,Chen J,Guo F
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Mon May 01 00:00:00 UTC 2023
Sustained release of therapeutic gene by injectable hydrogel for hepatocellular carcinoma.
International journal of pharmaceutics: X
Xu S,Cai J,Cheng H,Wang W
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Fri Dec 15 00:00:00 UTC 2023
Therapeutically targeting type I interferon directly to XCR1+ dendritic cells reveals the role of cDC1s in anti-drug antibodies.
Frontiers in immunology
Noe P,Wang JH,Chung K,Cheng Z,Field JJ,Shen X,Cortesio CL,Pastuskovas CV,Phee H,Tarbell KV,Egen JG,Casbon AJ
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Fri Nov 10 00:00:00 UTC 2023
Contribution of Mesenchymal Stem Cells from Obese Adipose Tissue to PD-L1 Over-Expression and Breast Cancer Progression through Pathogenic Th17 Cell Activation.
Cancers
Blangero F,Robert M,Andraud T,Dumontet C,Vidal H,Eljaafari A
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Mon May 29 00:00:00 UTC 2023
DNAJB4 suppresses breast cancer progression and promotes tumor immunity by regulating the Hippo signaling pathway.
Discover oncology
Chen Y,Li J,Pu L,Hu J,Fang L,Zhou F,Zhang H,Yang Y,Rong X,Deng S,Hou L
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Immunohistochemistry
Mon Aug 07 00:00:00 UTC 2023
BRAF D594A mutation defines a unique biological and immuno-modulatory subgroup associated with functional CD8+ T cell infiltration in colorectal cancer.
Journal of translational medicine
Li W,Zhao C,Li W,Gong Y,Ma K,Lu Y,Liu X,Zhang L,Guo F
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Wed Oct 18 00:00:00 UTC 2023
P. gingivalis Infection Upregulates PD-L1 Expression on Dendritic Cells, Suppresses CD8+ T-cell Responses, and Aggravates Oral Cancer.
Cancer immunology research
Ren J,Han X,Lohner H,Hoyle RG,Li J,Liang S,Wang H
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Wed Mar 01 00:00:00 UTC 2023
IFNAR blockade synergizes with oncolytic VSV to prevent virus-mediated PD-L1 expression and promote antitumor T cell activity.
Molecular therapy oncolytics
El-Sayes N,Walsh S,Vito A,Reihani A,Ask K,Wan Y,Mossman K
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Immunohistochemistry
Thu Jun 16 00:00:00 UTC 2022
Modification of PLAC8 by UFM1 affects tumorous proliferation and immune response by impacting PD-L1 levels in triple-negative breast cancer.
Journal for immunotherapy of cancer
Mao M,Chen Y,Yang J,Cheng Y,Xu L,Ji F,Zhou J,Zhang X,Li Z,Chen C,Ju S,Zhang J,Wang L
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Thu Dec 01 00:00:00 UTC 2022
Heterogeneity of tyrosine-based melanin anabolism regulates pulmonary and cerebral organotropic colonization microenvironment of melanoma cells.
Theranostics
Wang X,Chen Y,Lan B,Wang Y,Lin W,Jiang X,Ye J,Shang B,Feng C,Liu J,Zhai J,Xu M,Li Q,Lin L,Hu M,Zheng F,Chen L,Shao C,Wang Y,Shi Y
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Thu Apr 21 00:00:00 UTC 2022
CD4+ CTLs Act as a Key Effector Population for Allograft Rejection of MSCs in a Donor MHC-II Dependent Manner in Injured Liver.
Aging and disease
Shen S,Li Y,Jin M,Fan D,Pan R,Lin A,Chen Y,Xiang L,Zhao RC,Shao J
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Thu Dec 01 00:00:00 UTC 2022
5-Azacytidine-Mediated Modulation of the Immune Microenvironment in Murine Acute Myeloid Leukemia.
Cancers
Ebelt ND,Manuel ER
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Sun Dec 25 00:00:00 UTC 2022
Scoring model based on the signature of non-m6A-related neoantigen-coding lncRNAs assists in immune microenvironment analysis and TCR-neoantigen pair selection in gliomas.
Journal of translational medicine
Zhao W,Wu Y,Zhao F,Xue Z,Liu W,Cao Z,Zhao Z,Huang B,Han M,Li X
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Immunohistochemistry
Sat Oct 29 00:00:00 UTC 2022
Isotope tracing reveals distinct substrate preference in murine melanoma subtypes with differing anti-tumor immunity.
Cancer & metabolism
Zhang X,Halberstam AA,Zhu W,Leitner BP,Thakral D,Bosenberg MW,Perry RJ
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Thu Dec 01 00:00:00 UTC 2022
Multiscale imaging of therapeutic anti-PD-L1 antibody localization using molecularly defined imaging agents.
Journal of nanobiotechnology
Hagemans IM,Wierstra PJ,Steuten K,Molkenboer-Kuenen JDM,van Dalen D,Ter Beest M,van der Schoot JMS,Ilina O,Gotthardt M,Figdor CG,Scheeren FA,Heskamp S,Verdoes M
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Wed Feb 02 00:00:00 UTC 2022
Radiation-induced abscopal effect and its enhancement by programmed cell death 1 blockade in the hepatocellular carcinoma: A murine model study.
Clinical and molecular hepatology
Yoo GS,Ahn WG,Kim SY,Kang W,Choi C,Park HC
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Fri Jan 01 00:00:00 UTC 2021
Oncolytic herpes simplex virus HF10 (canerpaturev) promotes accumulation of CD8+ PD-1- tumor-infiltrating T cells in PD-L1-enriched tumor microenvironment.
International journal of cancer
Eissa IR,Mukoyama N,Abdelmoneim M,Naoe Y,Matsumura S,Bustos-Villalobos I,Ichinose T,Miyajima N,Morimoto D,Tanaka M,Fujimoto Y,Sone M,Kodera Y,Kasuya H
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Thu Jul 01 00:00:00 UTC 2021
Preclinical characterization of bemarituzumab, an anti-FGFR2b antibody for the treatment of cancer.
mAbs
Xiang H,Chan AG,Ahene A,Bellovin DI,Deng R,Hsu AW,Jeffry U,Palencia S,Powers J,Zanghi J,Collins H
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Immunocytochemistry
Mon Apr 04 00:00:00 UTC 2022
Collagenase-Expressing Salmonella Targets Major Collagens in Pancreatic Cancer Leading to Reductions in Immunosuppressive Subsets and Tumor Growth.
Cancers
Ebelt ND,Zamloot V,Zuniga E,Passi KB,Sobocinski LJ,Young CA,Blazar BR,Manuel ER
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Fri Jul 16 00:00:00 UTC 2021
N-cadherin inhibitor creates a microenvironment that protect TILs from immune checkpoints and Treg cells.
Journal for immunotherapy of cancer
Sun Y,Jing J,Xu H,Xu L,Hu H,Tang C,Liu S,Wei Q,Duan R,Guo J,Yang L
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Neutralization
Mon Mar 01 00:00:00 UTC 2021
N-cadherin inhibitor creates a microenvironment that protect TILs from immune checkpoints and Treg cells.
Journal for immunotherapy of cancer
Sun Y,Jing J,Xu H,Xu L,Hu H,Tang C,Liu S,Wei Q,Duan R,Guo J,Yang L
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Neutralization
Mon Mar 01 00:00:00 UTC 2021
N-cadherin inhibitor creates a microenvironment that protect TILs from immune checkpoints and Treg cells.
Journal for immunotherapy of cancer
Sun Y,Jing J,Xu H,Xu L,Hu H,Tang C,Liu S,Wei Q,Duan R,Guo J,Yang L
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Neutralization
Mon Mar 01 00:00:00 UTC 2021
Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade.
JCI insight
Ferrere G,Tidjani Alou M,Liu P,Goubet AG,Fidelle M,Kepp O,Durand S,Iebba V,Fluckiger A,Daillère R,Thelemaque C,Grajeda-Iglesias C,Alves Costa Silva C,Aprahamian F,Lefevre D,Zhao L,Ryffel B,Colomba E,Arnedos M,Drubay D,Rauber C,Raoult D,Asnicar F,Spector T,Segata N,Derosa L,Kroemer G,Zitvogel L
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Mon Jan 25 00:00:00 UTC 2021
Progranulin induces immune escape in breast cancer via up-regulating PD-L1 expression on tumor-associated macrophages (TAMs) and promoting CD8+ T cell exclusion.
Journal of experimental & clinical cancer research : CR
Fang W,Zhou T,Shi H,Yao M,Zhang D,Qian H,Zeng Q,Wang Y,Jin F,Chai C,Chen T
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Neutralization
Mon Jan 04 00:00:00 UTC 2021
Progranulin induces immune escape in breast cancer via up-regulating PD-L1 expression on tumor-associated macrophages (TAMs) and promoting CD8+ T cell exclusion.
Journal of experimental & clinical cancer research : CR
Fang W,Zhou T,Shi H,Yao M,Zhang D,Qian H,Zeng Q,Wang Y,Jin F,Chai C,Chen T
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Neutralization
Mon Jan 04 00:00:00 UTC 2021
USP12 downregulation orchestrates a protumourigenic microenvironment and enhances lung tumour resistance to PD-1 blockade.
Nature communications
Yang Z,Xu G,Wang B,Liu Y,Zhang L,Jing T,Tang M,Xu X,Jiao K,Xiang L,Fu Y,Tang D,Zhang X,Jin W,Zhuang G,Zhao X,Liu Y
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Wed Aug 11 00:00:00 UTC 2021
Antigen-Capturing Mesoporous Silica Nanoparticles Enhance the Radiation-Induced Abscopal Effect in Murine Hepatocellular Carcinoma Hepa1-6 Models.
Pharmaceutics
Yang K,Choi C,Cho H,Ahn WG,Kim SY,Shin SW,Kim Y,Jang T,Lee N,Park HC
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Fri Oct 29 00:00:00 UTC 2021
Downregulation of PD-L1 via amide analogues of brefelamide: Alternatives to antibody-based cancer immunotherapy.
Experimental and therapeutic medicine
Zhang J,Yamada O,Kida S,Murase S,Hattori T,Oshima Y,Kikuchi H
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Wed Apr 01 00:00:00 UTC 2020
Genetic ablation of adipocyte PD-L1 reduces tumor growth but accentuates obesity-associated inflammation.
Journal for immunotherapy of cancer
Wu B,Chiang HC,Sun X,Yuan B,Mitra P,Hu Y,Curiel TJ,Li R
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Sat Aug 01 00:00:00 UTC 2020
Cancer cell-intrinsic expression of MHC II in lung cancer cell lines is actively restricted by MEK/ERK signaling and epigenetic mechanisms.
Journal for immunotherapy of cancer
Neuwelt AJ,Kimball AK,Johnson AM,Arnold BW,Bullock BL,Kaspar RE,Kleczko EK,Kwak JW,Wu MH,Heasley LE,Doebele RC,Li HY,Nemenoff RA,Clambey ET
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Wed Apr 01 00:00:00 UTC 2020
CD279 mediates the homeostasis and survival of regulatory T cells by enhancing T cell and macrophage interactions.
FEBS open bio
Liu Y,Gao Y,Hao H,Hou T
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Functional assay
Mon Jun 01 00:00:00 UTC 2020
CD279 mediates the homeostasis and survival of regulatory T cells by enhancing T cell and macrophage interactions.
FEBS open bio
Liu Y,Gao Y,Hao H,Hou T
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Functional assay
Mon Jun 01 00:00:00 UTC 2020
MicroRNA-200a induces immunosuppression by promoting PTEN-mediated PD-L1 upregulation in osteosarcoma.
Aging
Liu Z,Wen J,Wu C,Hu C,Wang J,Bao Q,Wang H,Wang J,Zhou Q,Wei L,Shen Y,Zhang W
16-5982 was used in Flow cytometry/Cell sorting to provide important and novel insight into a regulatory axis involving microRNA-200a/PTEN/ PD-L1 axis, which determines osteosarcoma growth and the efficacy of PD-L1-targeted immunotherapy.
Fri Jan 24 00:00:00 UTC 2020
Nuclear imaging-guided PD-L1 blockade therapy increases effectiveness of cancer immunotherapy.
Journal for immunotherapy of cancer
Gao H,Wu Y,Shi J,Zhang X,Liu T,Hu B,Jia B,Wan Y,Liu Z,Wang F
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Sun Nov 01 00:00:00 UTC 2020
Epigenetically modulated FOXM1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer.
Molecular oncology
Zhou Z,Chen H,Xie R,Wang H,Li S,Xu Q,Xu N,Cheng Q,Qian Y,Huang R,Shao Z,Xiang M
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Mon Apr 01 00:00:00 UTC 2019
Tumor-intrinsic response to IFNγ shapes the tumor microenvironment and anti-PD-1 response in NSCLC.
Life science alliance
Bullock BL,Kimball AK,Poczobutt JM,Neuwelt AJ,Li HY,Johnson AM,Kwak JW,Kleczko EK,Kaspar RE,Wagner EK,Hopp K,Schenk EL,Weiser-Evans MC,Clambey ET,Nemenoff RA
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Sat Jun 01 00:00:00 UTC 2019
Inhibition of ATM reverses EMT and decreases metastatic potential of cisplatin-resistant lung cancer cells through JAK/STAT3/PD-L1 pathway.
Journal of experimental & clinical cancer research : CR
Shen M,Xu Z,Xu W,Jiang K,Zhang F,Ding Q,Xu Z,Chen Y
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Neutralization
Mon Apr 08 00:00:00 UTC 2019
Inhibition of ATM reverses EMT and decreases metastatic potential of cisplatin-resistant lung cancer cells through JAK/STAT3/PD-L1 pathway.
Journal of experimental & clinical cancer research : CR
Shen M,Xu Z,Xu W,Jiang K,Zhang F,Ding Q,Xu Z,Chen Y
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Neutralization
Mon Apr 08 00:00:00 UTC 2019
PD-L1 in tumor microenvironment mediates resistance to oncolytic immunotherapy.
The Journal of clinical investigation
Zamarin D,Ricca JM,Sadekova S,Oseledchyk A,Yu Y,Blumenschein WM,Wong J,Gigoux M,Merghoub T,Wolchok JD
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Mon Apr 02 00:00:00 UTC 2018
The antitumor effects of entinostat in ovarian cancer require adaptive immunity.
Cancer
Smith HJ,McCaw TR,Londono AI,Katre AA,Meza-Perez S,Yang ES,Forero A,Buchsbaum DJ,Randall TD,Straughn JM,Norian LA,Arend RC
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Sat Dec 15 00:00:00 UTC 2018
Increased infiltration of macrophages to radioresistant lung cancer cells contributes to the development of the additional resistance of tumor cells to the cytotoxic effects of NK cells.
International journal of oncology
Shen M,Chen Y,Xu L,Zhu R,Xue X,Tsai Y,Keng PC,Lee SO,Chen Y
16-5982-82 was used in Neutralization to suggest the existence of a malignant loop characterized by increased macrophage infiltration into radioresistant lung cancer cells which, in turn, promotes the development of the additional resistance of these cells to NK cell cytotoxicity.
Sun Jul 01 00:00:00 UTC 2018
ATM‑JAK‑PD‑L1 signaling pathway inhibition decreases EMT and metastasis of androgen‑independent prostate cancer.
Molecular medicine reports
Zhang L,Xu LJ,Zhu J,Li J,Xue BX,Gao J,Sun CY,Zang YC,Zhou YB,Yang DR,Shan YX
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Immunofluorescence
Tue May 01 00:00:00 UTC 2018
Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion.
Nature communications
Sun C,Lan P,Han Q,Huang M,Zhang Z,Xu G,Song J,Wang J,Wei H,Zhang J,Sun R,Zhang C,Tian Z
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Wed Mar 28 00:00:00 UTC 2018
Homeostatic control of metabolic and functional fitness of Treg cells by LKB1 signalling.
Nature
Yang K,Blanco DB,Neale G,Vogel P,Avila J,Clish CB,Wu C,Shrestha S,Rankin S,Long L,Kc A,Chi H
16-5982 was used in Inhibition experiments to show that liver kinase B1 programs the metabolic and functional fitness of Treg cells in the control of immune tolerance and homeostasis.
Thu Aug 31 00:00:00 UTC 2017
Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNA.
Immunity
Coelho MA,de Carné Trécesson S,Rana S,Zecchin D,Moore C,Molina-Arcas M,East P,Spencer-Dene B,Nye E,Barnouin K,Snijders AP,Lai WS,Blackshear PJ,Downward J
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Tue Dec 19 00:00:00 UTC 2017
Neuronal IFN-beta-induced PI3K/Akt-FoxA1 signalling is essential for generation of FoxA1+Treg cells.
Nature communications
Liu Y,Marin A,Ejlerskov P,Rasmussen LM,Prinz M,Issazadeh-Navikas S
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Western Blot
Mon Apr 24 00:00:00 UTC 2017
Neuronal IFN-beta-induced PI3K/Akt-FoxA1 signalling is essential for generation of FoxA1+Treg cells.
Nature communications
Liu Y,Marin A,Ejlerskov P,Rasmussen LM,Prinz M,Issazadeh-Navikas S
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Western Blot
Mon Apr 24 00:00:00 UTC 2017
Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression.
Nature communications
Kalkavan H,Sharma P,Kasper S,Helfrich I,Pandyra AA,Gassa A,Virchow I,Flatz L,Brandenburg T,Namineni S,Heikenwalder M,Höchst B,Knolle PA,Wollmann G,von Laer D,Drexler I,Rathbun J,Cannon PM,Scheu S,Bauer J,Chauhan J,Häussinger D,Willimsky G,Löhning M,Schadendorf D,Brandau S,Schuler M,Lang PA,Lang KS
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Immunofluorescence
Wed Mar 01 00:00:00 UTC 2017
Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission.
Immunity
Tian Y,Kuo CF,Akbari O,Ou JH
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Tue May 17 00:00:00 UTC 2016
Recruited monocytes modulate malaria-induced lung injury through CD36-mediated clearance of sequestered infected erythrocytes.
Journal of leukocyte biology
Lagassé HA,Anidi IU,Craig JM,Limjunyawong N,Poupore AK,Mitzner W,Scott AL
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Sun May 01 00:00:00 UTC 2016
Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology.
PloS one
Selby MJ,Engelhardt JJ,Johnston RJ,Lu LS,Han M,Thudium K,Yao D,Quigley M,Valle J,Wang C,Chen B,Cardarelli PM,Blanset D,Korman AJ
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Immunohistochemistry
Fri Aug 25 00:00:00 UTC 2017
Exploring the induction of preproinsulin-specific Foxp3(+) CD4(+) Treg cells that inhibit CD8(+) T cell-mediated autoimmune diabetes by DNA vaccination.
Scientific reports
Stifter K,Schuster C,Schlosser M,Boehm BO,Schirmbeck R
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Neutralization
Mon Jul 11 00:00:00 UTC 2016
Exploring the induction of preproinsulin-specific Foxp3(+) CD4(+) Treg cells that inhibit CD8(+) T cell-mediated autoimmune diabetes by DNA vaccination.
Scientific reports
Stifter K,Schuster C,Schlosser M,Boehm BO,Schirmbeck R
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Neutralization
Mon Jul 11 00:00:00 UTC 2016
PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation.
The Journal of experimental medicine
Noman MZ,Desantis G,Janji B,Hasmim M,Karray S,Dessen P,Bronte V,Chouaib S
16-5982 was used in Neutralization experiments to determine that blockage of the HRE within the proximal promoter of PD-1 ligand causes preferential anticancer MDSC determination.
Mon May 05 00:00:00 UTC 2014
A mechanism of hypoxia-mediated escape from adaptive immunity in cancer cells.
Cancer research
Barsoum IB,Smallwood CA,Siemens DR,Graham CH
16-5982 was used in Blocking experiments to investigate whether exposure of mouse and human tumour cells to hypoxia increases their resistance to T cell-mediated immunity.
Sat Feb 01 00:00:00 UTC 2014
Targeting immune co-stimulatory effects of PD-L1 and PD-L2 might represent an effective therapeutic strategy in stroke.
Frontiers in cellular neuroscience
Bodhankar S,Chen Y,Lapato A,Vandenbark AA,Murphy SJ,Offner H
16-5982 was used in Flow cytometry/Cell sorting to investigate PD-L1 and PD-L2 expressing cell types that affect T-cell activation post stroke, and how these could be targeted therapeutically.
Tue Aug 26 00:00:00 UTC 2014
Ex vivo expanded hematopoietic stem cells overcome the MHC barrier in allogeneic transplantation.
Cell stem cell
Zheng J,Umikawa M,Zhang S,Huynh H,Silvany R,Chen BP,Chen L,Zhang CC
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Neutralization
Fri Aug 05 00:00:00 UTC 2011
Ex vivo expanded hematopoietic stem cells overcome the MHC barrier in allogeneic transplantation.
Cell stem cell
Zheng J,Umikawa M,Zhang S,Huynh H,Silvany R,Chen BP,Chen L,Zhang CC
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Neutralization
Fri Aug 05 00:00:00 UTC 2011
Farnesyltransferase inhibitor FTI-277 reduces mortality of septic mice along with improved bacterial clearance.
The Journal of pharmacology and experimental therapeutics
Yang W,Yamada M,Tamura Y,Chang K,Mao J,Zou L,Feng Y,Kida K,Scherrer-Crosbie M,Chao W,Ichinose F,Yu YM,Fischman AJ,Tompkins RG,Yao S,Kaneki M
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 16-5982-82) in Flow Cytometry
Thu Dec 01 00:00:00 UTC 2011
Antigen-specific immunity and cross-priming by epithelial ovarian carcinoma-induced CD11b(+)Gr-1(+) cells.
Journal of immunology (Baltimore, Md. : 1950)
Tomihara K,Guo M,Shin T,Sun X,Ludwig SM,Brumlik MJ,Zhang B,Curiel TJ,Shin T
16-5982 was used in Blocking experiments to investigate CD11b(+)Gr-1(+) cells found in epithelial ovarian cancer-bearing mice, which are induced by ovarian cancer cells and undergo antigen-specific immunity and cross-priming.
Tue Jun 01 00:00:00 UTC 2010
Control of established melanoma by CD27 stimulation is associated with enhanced effector function and persistence, and reduced PD-1 expression of tumor infiltrating CD8(+) T cells.
Journal of immunotherapy (Hagerstown, Md. : 1997)
Roberts DJ,Franklin NA,Kingeter LM,Yagita H,Tutt AL,Glennie MJ,Bullock TN
16-5982 was used in in vitro experiments to examine the efficacy of agonistic anti-CD27 antibodies as monotherapies for established melanoma in a murine model.
Fri Oct 01 00:00:00 UTC 2010
Control of established melanoma by CD27 stimulation is associated with enhanced effector function and persistence, and reduced PD-1 expression of tumor infiltrating CD8(+) T cells.
Journal of immunotherapy (Hagerstown, Md. : 1997)
Roberts DJ,Franklin NA,Kingeter LM,Yagita H,Tutt AL,Glennie MJ,Bullock TN
16-5982 was used in in vitro experiments to examine the efficacy of agonistic anti-CD27 antibodies as monotherapies for established melanoma in a murine model.
Fri Oct 01 00:00:00 UTC 2010
A critical role of IFNgamma in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1.
Cell research
Sheng H,Wang Y,Jin Y,Zhang Q,Zhang Y,Wang L,Shen B,Yin S,Liu W,Cui L,Li N
Fri Aug 01 00:00:00 UTC 2008
Murine isolated lymphoid follicles contain follicular B lymphocytes with a mucosal phenotype.
American journal of physiology. Gastrointestinal and liver physiology
Wang C,McDonald KG,McDonough JS,Newberry RD
16-5982 was used in Flow cytometry/Cell sorting to indicate that murine ILFs contain a polyclonal population of follicular B-2 B lymphocytes with a phenotype similar to PP B lymphocytes.
Sun Oct 01 00:00:00 UTC 2006
-Functional-Grade-Flow-20170216130641.jpg?time=20220826)
-Functional-Grade-Flow-20170216130641.jpg?time=20220826?time=20220826 "CD274 (PD-L1, B7-H1) Antibody (16-5982-82) in Flow")
