Product References
Antigen-Specific Intraocular Cytokine Responses Distinguish Ocular Tuberculosis From Undifferentiated Uveitis in Tuberculosis-Immunoreactive Patients.
American journal of ophthalmology
Alam K,Sharma G,Forrester JV,Basu S
48-7349-42 was used in Flow cytometry/Cell sorting to show that the intraocular polyfunctional cytokine response is stronger in undifferentiated TST+ uveitis than in OTB patients, likely representing an exaggerated anti-TB immune response rather than active infection.
Wed Feb 01 00:00:00 UTC 2023
The effect of metformin on senescence of T lymphocytes.
Immunity & ageing : I & A
Yang J,Liu HC,Zhang JQ,Zou JY,Zhang X,Chen WM,Gu Y,Hong H
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Tue Dec 12 00:00:00 UTC 2023
Dynamics of humoral and cellular response to three doses of anti-SARS-CoV-2 BNT162b2 vaccine in patients with hematological malignancies and older subjects.
Frontiers in immunology
Laquintana V,Mottini C,Marchesi F,Marcozzi B,Terrenato I,Sperandio E,de Latouliere L,Carrieri F,Pimpinelli F,Pontone M,Pellini R,Campo F,Conti L,Accetta C,Mandoj C,Petrone F,Di Bella O,Vujovic B,Morrone A,Compagnone M,Principato E,Pinto E,Papa E,Falcucci P,La Malfa A,Pallocca M,De Marco F,Piaggio G,Ciliberto G,Mengarelli A,di Martino S
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Wed Feb 14 00:00:00 UTC 2024
R274X-mutated Phf6 increased the self-renewal and skewed T cell differentiation of hematopoietic stem cells.
iScience
Lan Y,Yuan S,Guo T,Hou S,Zhao F,Yang W,Cao Y,Chu Y,Jiang E,Yuan W,Wang X
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Fri Jun 16 00:00:00 UTC 2023
An epitope encoded by uORF of RNF10 elicits a therapeutic anti-tumor immune response.
Molecular therapy oncolytics
Zeng L,Zheng W,Zhang J,Wang J,Ji Q,Wu X,Meng Y,Zhu X
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Tue Dec 19 00:00:00 UTC 2023
Targeted multi-omic analysis of human skin tissue identifies alterations of conventional and unconventional T cells associated with burn injury.
eLife
Labuz DR,Lewis G,Fleming ID,Thompson CM,Zhai Y,Firpo MA,Leung DT
48-7349-42 was used in Flow cytometry/Cell sorting to suggest that T cells in burn tissue have a pro-inflammatory rather than a homeostatic tissue-resident phenotype, and that unconventional T cells have a higher cytotoxic capacity.
Wed Feb 15 00:00:00 UTC 2023
Immunological memory to common cold coronaviruses assessed longitudinally over a three-year period pre-COVID19 pandemic.
Cell host & microbe
Yu ED,Narowski TM,Wang E,Garrigan E,Mateus J,Frazier A,Weiskopf D,Grifoni A,Premkumar L,da Silva Antunes R,Sette A
48-7349-42 was used in Flow cytometry/Cell sorting to understand the immune response to endemic coronaviruses and suggest that steady and sustainedcommon cold coronaviruses responses are likely from a stable pool of memory CD4+ T cells due to repeated earlier exposures and possibly occasional reinfections.
Wed Sep 14 00:00:00 UTC 2022
NVX-CoV2373 vaccination induces functional SARS-CoV-2-specific CD4+ and CD8+ T cell responses.
The Journal of clinical investigation
Rydyznski Moderbacher C,Kim C,Mateus J,Plested J,Zhu M,Cloney-Clark S,Weiskopf D,Sette A,Fries L,Glenn G,Crotty S
48-7349-42 was used in Flow cytometry/Cell sorting to demonstrate that vaccinated subjects made CD4+ T cell responses after one and two doses of NVX-CoV2373, and a subset of individuals made CD8+ T cell responses.
Mon Oct 03 00:00:00 UTC 2022
LINC01123 promotes immune escape by sponging miR-214-3p to regulate B7-H3 in head and neck squamous-cell carcinoma.
Cell death & disease
Li H,Yang Z,Yang X,Zhang F,Wang J,Wu Z,Wanyan C,Meng Q,Gao W,Yang X,Wei J
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Thu Feb 03 00:00:00 UTC 2022
PRDM1/BLIMP1 induces cancer immune evasion by modulating the USP22-SPI1-PD-L1 axis in hepatocellular carcinoma cells.
Nature communications
Li Q,Zhang L,You W,Xu J,Dai J,Hua D,Zhang R,Yao F,Zhou S,Huang W,Dai Y,Zhang Y,Baheti T,Qian X,Pu L,Xu J,Xia Y,Zhang C,Tang J,Wang X
48-7349-42 was used in Flow cytometry/Cell sorting to demonstrate that the PRDM1-USP22-SPI1 axis regulates PD-L1 levels, resulting in infiltrated CD8+ T cell exhaustion.
Mon Dec 12 00:00:00 UTC 2022
PRDM1/BLIMP1 induces cancer immune evasion by modulating the USP22-SPI1-PD-L1 axis in hepatocellular carcinoma cells.
Nature communications
Li Q,Zhang L,You W,Xu J,Dai J,Hua D,Zhang R,Yao F,Zhou S,Huang W,Dai Y,Zhang Y,Baheti T,Qian X,Pu L,Xu J,Xia Y,Zhang C,Tang J,Wang X
48-7349-42 was used in Flow cytometry/Cell sorting to demonstrate that the PRDM1-USP22-SPI1 axis regulates PD-L1 levels, resulting in infiltrated CD8+ T cell exhaustion.
Mon Dec 12 00:00:00 UTC 2022
PRDM1/BLIMP1 induces cancer immune evasion by modulating the USP22-SPI1-PD-L1 axis in hepatocellular carcinoma cells.
Nature communications
Li Q,Zhang L,You W,Xu J,Dai J,Hua D,Zhang R,Yao F,Zhou S,Huang W,Dai Y,Zhang Y,Baheti T,Qian X,Pu L,Xu J,Xia Y,Zhang C,Tang J,Wang X
48-7349-42 was used in Flow cytometry/Cell sorting to demonstrate that the PRDM1-USP22-SPI1 axis regulates PD-L1 levels, resulting in infiltrated CD8+ T cell exhaustion.
Mon Dec 12 00:00:00 UTC 2022
Enhanced antibody responses in fully vaccinated individuals against pan-SARS-CoV-2 variants following Omicron breakthrough infection.
Cell reports. Medicine
Jeong HW,Kim SM,Jung MK,Noh JY,Yoo JS,Kim EH,Kim YI,Yu K,Jang SG,Gil J,Casel MA,Rare R,Choi JH,Kim HS,Kim JH,Um J,Kim C,Kim Y,Chin BS,Jung S,Choi JY,Song KH,Kim YD,Park JS,Song JY,Shin EC,Choi YK
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Tue Oct 18 00:00:00 UTC 2022
SARS-CoV-2 vaccination induces immunological T cell memory able to cross-recognize variants from Alpha to Omicron.
Cell
Tarke A,Coelho CH,Zhang Z,Dan JM,Yu ED,Methot N,Bloom NI,Goodwin B,Phillips E,Mallal S,Sidney J,Filaci G,Weiskopf D,da Silva Antunes R,Crotty S,Grifoni A,Sette A
48-7349-42 was used in Flow Cytometry to address whether T cell responses induced by different vaccine platforms (mRNA-1273, BNT162b2, Ad26.COV2.S, and NVX-CoV2373) cross-recognize early SARS-CoV-2 variants.
Thu Mar 03 00:00:00 UTC 2022
Humoral and cellular immune memory to four COVID-19 vaccines.
Cell
Zhang Z,Mateus J,Coelho CH,Dan JM,Moderbacher CR,Gálvez RI,Cortes FH,Grifoni A,Tarke A,Chang J,Escarrega EA,Kim C,Goodwin B,Bloom NI,Frazier A,Weiskopf D,Sette A,Crotty S
48-7349-42 was used in flow cytometry to investigate SARS-CoV-2-spike-specific immune responses to Moderna mRNA-1273, Pfizer/BioNTech BNT162b2, Janssen Ad26.COV2.S, and Novavax NVX-CoV2373.
Thu Jul 07 00:00:00 UTC 2022
Dissecting the role of CSF2RB expression in human regulatory T cells.
Frontiers in immunology
Côrte-Real BF,Arroyo Hornero R,Dyczko A,Hamad I,Kleinewietfeld M
48-7349-42 was used in Flow Cytometry to identify Treg subpopulations from pools of activated CD4+ T cells and demonstrate the overexpression of CSF2RB in Tregs of patients with autoimmune diseases like MS and SLE, thereby indicating that CSF2RB expression in Tregs could serve as a potential novel biomarker for disease.
Tue Dec 20 00:00:00 UTC 2022
Early and Polyantigenic CD4 T Cell Responses Correlate with Mild Disease in Acute COVID-19 Donors.
International journal of molecular sciences
Tarke A,Potesta M,Varchetta S,Fenoglio D,Iannetta M,Sarmati L,Mele D,Dentone C,Bassetti M,Montesano C,Mondelli MU,Filaci G,Grifoni A,Sette A
48-7349-42 was used in Flow cytometry/Cell sorting to highlight that both the magnitude and breadth of early SARS-CoV-2-specific CD4+ T cell responses correlated with milder disease outcomes in acute COVID-19 patients.
Tue Jun 28 00:00:00 UTC 2022
Defining antigen targets to dissect vaccinia virus and monkeypox virus-specific T cell responses in humans.
Cell host & microbe
Grifoni A,Zhang Y,Tarke A,Sidney J,Rubiro P,Reina-Campos M,Filaci G,Dan JM,Scheuermann RH,Sette A
48-7349-42 was used in Flow cytometry/Cell sorting to predict potential monkeypox virus (MPXV) targets recognized by CD4+ and CD8+ T cell responses based on vaccinia virus (VACV) epitopes, revealing a high degree of conservation between VACV and MPXV epitopes, which allowed the design of peptide pools to detect VACV-specific T cell responses and cross-reactive T cells in vaccinated individuals.
Wed Dec 14 00:00:00 UTC 2022
Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques.
Cell
Hoang TN,Pino M,Boddapati AK,Viox EG,Starke CE,Upadhyay AA,Gumber S,Nekorchuk M,Busman-Sahay K,Strongin Z,Harper JL,Tharp GK,Pellegrini KL,Kirejczyk S,Zandi K,Tao S,Horton TR,Beagle EN,Mahar EA,Lee MYH,Cohen J,Jean SM,Wood JS,Connor-Stroud F,Stammen RL,Delmas OM,Wang S,Cooney KA,Sayegh MN,Wang L,Filev PD,Weiskopf D,Silvestri G,Waggoner J,Piantadosi A,Kasturi SP,Al-Shakhshir H,Ribeiro SP,Sekaly RP,Levit RD,Estes JD,Vanderford TH,Schinazi RF,Bosinger SE,Paiardini M
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Thu Jan 21 00:00:00 UTC 2021
Membrane lymphotoxin-α2β is a novel tumor necrosis factor (TNF) receptor 2 (TNFR2) agonist.
Cell death & disease
Kucka K,Lang I,Zhang T,Siegmund D,Medler J,Wajant H
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Tue Apr 06 00:00:00 UTC 2021
NKD2 mediates stimulation-dependent ORAI1 trafficking to augment Ca2+ entry in T cells.
Cell reports
Wu B,Woo JS,Vila P,Jew M,Leung J,Sun Z,Srikanth S,Gwack Y
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Tue Aug 24 00:00:00 UTC 2021
Development of an Inflammatory CD14+ Dendritic Cell Subset in Humanized Mice.
Frontiers in immunology
Iwabuchi R,Ide K,Terahara K,Wagatsuma R,Iwaki R,Matsunaga H,Tsunetsugu-Yokota Y,Takeyama H,Takahashi Y
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Mon Sep 27 00:00:00 UTC 2021
Cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapy.
Nature medicine
Apostolidis SA,Kakara M,Painter MM,Goel RR,Mathew D,Lenzi K,Rezk A,Patterson KR,Espinoza DA,Kadri JC,Markowitz DM,E Markowitz C,Mexhitaj I,Jacobs D,Babb A,Betts MR,Prak ETL,Weiskopf D,Grifoni A,Lundgreen KA,Gouma S,Sette A,Bates P,Hensley SE,Greenplate AR,Wherry EJ,Li R,Bar-Or A
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Mon Nov 01 00:00:00 UTC 2021
Rejuvenating Effector/Exhausted CAR T Cells to Stem Cell Memory-Like CAR T Cells By Resting Them in the Presence of CXCL12 and the NOTCH Ligand.
Cancer research communications
Ando M,Kondo T,Tomisato W,Ito M,Shichino S,Srirat T,Mise-Omata S,Nakagawara K,Yoshimura A
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Fri Oct 01 00:00:00 UTC 2021
Inhibition of Cholesterol Esterification Enzyme Enhances the Potency of Human Chimeric Antigen Receptor T Cells against Pancreatic Carcinoma.
Molecular therapy oncolytics
Zhao L,Liu Y,Zhao F,Jin Y,Feng J,Geng R,Sun J,Kang L,Yu L,Wei Y
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Fri Mar 27 00:00:00 UTC 2020
Abrogation of HLA surface expression using CRISPR/Cas9 genome editing: a step toward universal T cell therapy.
Scientific reports
Lee J,Sheen JH,Lim O,Lee Y,Ryu J,Shin D,Kim YY,Kim M
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Tue Oct 20 00:00:00 UTC 2020
Ghrelin ameliorates tumor-induced adipose tissue atrophy and inflammation via Ghrelin receptor-dependent and -independent pathways.
Oncotarget
Liu H,Luo J,Guillory B,Chen JA,Zang P,Yoeli JK,Hernandez Y,Lee II,Anderson B,Storie M,Tewnion A,Garcia JM
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Immunohistochemistry
Tue Sep 01 00:00:00 UTC 2020
Mucosal-associated invariant T (MAIT) cells mediate protective host responses in sepsis.
eLife
Trivedi S,Labuz D,Anderson CP,Araujo CV,Blair A,Middleton EA,Jensen O,Tran A,Mulvey MA,Campbell RA,Hale JS,Rondina MT,Leung DT
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Mon Nov 09 00:00:00 UTC 2020
Mucosal-associated invariant T (MAIT) cells mediate protective host responses in sepsis.
eLife
Trivedi S,Labuz D,Anderson CP,Araujo CV,Blair A,Middleton EA,Jensen O,Tran A,Mulvey MA,Campbell RA,Hale JS,Rondina MT,Leung DT
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Mon Nov 09 00:00:00 UTC 2020
CAIX Regulates GBM Motility and TAM Adhesion and Polarization through EGFR/STAT3 under Hypoxic Conditions.
International journal of molecular sciences
Huang BR,Liu YS,Lai SW,Lin HJ,Shen CK,Yang LY,Lu DY
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Fri Aug 14 00:00:00 UTC 2020
TLR2 on blood monocytes senses dengue virus infection and its expression correlates with disease pathogenesis.
Nature communications
Aguilar-Briseño JA,Upasani V,Ellen BMT,Moser J,Pauzuolis M,Ruiz-Silva M,Heng S,Laurent D,Choeung R,Dussart P,Cantaert T,Smit JM,Rodenhuis-Zybert IA
48-7349 was used in Flow cytometry/Cell sorting to demonstrate that TLR2, together with its co-receptors CD14 and TLR6, is an innate sensor of dengue virus particles.
Tue Jun 23 00:00:00 UTC 2020
Robust T Cell Response Toward Spike, Membrane, and Nucleocapsid SARS-CoV-2 Proteins Is Not Associated with Recovery in Critical COVID-19 Patients.
Cell reports. Medicine
Thieme CJ,Anft M,Paniskaki K,Blazquez-Navarro A,Doevelaar A,Seibert FS,Hoelzer B,Konik MJ,Berger MM,Brenner T,Tempfer C,Watzl C,Meister TL,Pfaender S,Steinmann E,Dolff S,Dittmer U,Westhoff TH,Witzke O,Stervbo U,Roch T,Babel N
48-7349 was used in Flow cytometry/Cell sorting to indicate that activation of differentiated memory effector T cells could cause hyperreactivity and immunopathogenesis in critical patients.
Tue Sep 22 00:00:00 UTC 2020
Persistence of dysfunctional natural killer cells in adults with high-functioning autism spectrum disorders: stigma/consequence of unresolved early infectious events?
Molecular autism
Bennabi M,Tarantino N,Gaman A,Scheid I,Krishnamoorthy R,Debré P,Bouleau A,Caralp M,Gueguen S,Le-Moal ML,Bouvard M,Amestoy A,Delorme R,Leboyer M,Tamouza R,Vieillard V
48-7349 was used in Immunocytochemistry-immunoflourescence to explore the phenotype and polyfunctional capacities of NK cells according to infectious stigma and clinical parameters.
Wed Jun 17 00:00:00 UTC 2020
PD1 is expressed on exhausted T cells as well as virus specific memory CD8+ T cells in the bone marrow of myeloma patients.
Oncotarget
Sponaas AM,Yang R,Rustad EH,Standal T,Thoresen AS,Dao Vo C,Waage A,Slørdahl TS,Børset M,Sundan A
48-7349 was used in Flow cytometry to study the expression of PD-1 on exhausted T cells as well as virus specific memory CD8+ T cells in the bone marrow of myeloma patients.
Fri Aug 10 00:00:00 UTC 2018
A single centre phase II trial to assess the immunological activity of TroVax® plus pemetrexed/cisplatin in patients with malignant pleural mesothelioma - the SKOPOS trial.
Oncoimmunology
Lester JF,Casbard AC,Al-Taei S,Harrop R,Katona L,Attanoos RL,Tabi Z,Griffiths GO
48-7349-42 was used in Flow Cytometry to reveal a circulating baseline immune signature that was significantly associated with long-term (>20 months in n = 8/23, 34.8%) survival.
Sat Feb 10 00:00:00 UTC 2024
Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease.
Nature medicine
West NR,Hegazy AN,Owens BMJ,Bullers SJ,Linggi B,Buonocore S,Coccia M,Görtz D,This S,Stockenhuber K,Pott J,Friedrich M,Ryzhakov G,Baribaud F,Brodmerkel C,Cieluch C,Rahman N,Müller-Newen G,Owens RJ,Kühl AA,Maloy KJ,Plevy SE,Keshav S,Travis SPL,Powrie F
48-7349 was used in Flow cytometry/Cell sorting to study how cytokine oncostatin M is a potential biomarker and therapeutic target for IBD, and has particular relevance for anti-TNF-resistant patients.
Mon May 01 00:00:00 UTC 2017
Heterogeneous Tumor-Immune Microenvironments among Differentially Growing Metastases in an Ovarian Cancer Patient.
Cell
Jiménez-Sánchez A,Memon D,Pourpe S,Veeraraghavan H,Li Y,Vargas HA,Gill MB,Park KJ,Zivanovic O,Konner J,Ricca J,Zamarin D,Walther T,Aghajanian C,Wolchok JD,Sala E,Merghoub T,Snyder A,Miller ML
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Thu Aug 24 00:00:00 UTC 2017
The distribution and function of human memory T cell subsets in lung cancer.
Immunologic research
Sheng SY,Gu Y,Lu CG,Zou JY,Hong H,Wang R
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Thu Jun 01 00:00:00 UTC 2017
Application of a whole blood mycobacterial growth inhibition assay to study immunity against Mycobacterium tuberculosis in a high tuberculosis burden population.
PloS one
Baguma R,Penn-Nicholson A,Smit E,Erasmus M,Day J,Makhethe L,de Kock M,Hughes EJ,van Rooyen M,Pienaar B,Stone L,Hanekom W,Brennan MJ,Wallis RS,Hatherill M,Scriba TJ
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Wed Oct 18 00:00:00 UTC 2017
A Quantitative Analysis of Complexity of Human Pathogen-Specific CD4 T Cell Responses in Healthy M. tuberculosis Infected South Africans.
PLoS pathogens
Lindestam Arlehamn CS,McKinney DM,Carpenter C,Paul S,Rozot V,Makgotlho E,Gregg Y,van Rooyen M,Ernst JD,Hatherill M,Hanekom WA,Peters B,Scriba TJ,Sette A
48-7349 was used in Flow cytometry/Cell sorting to estimate the breadth of T cell responses for the first time in the context of an infection and human population setting.
Fri Jul 01 00:00:00 UTC 2016
Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells.
Journal of immunology (Baltimore, Md. : 1950)
Marquardt N,Béziat V,Nyström S,Hengst J,Ivarsson MA,Kekäläinen E,Johansson H,Mjösberg J,Westgren M,Lankisch TO,Wedemeyer H,Ellis EC,Ljunggren HG,Michaëlsson J,Björkström NK
48-7349 was used in Flow cytometry/Cell sorting to study the unique lineage of CD49a(+)DX5(-) NK cells, showing that they are readily detectable in the liver but not in hepatic venous or peripheral blood.
Sun Mar 15 00:00:00 UTC 2015
NCR(+)ILC3 concentrate in human lung cancer and associate with intratumoral lymphoid structures.
Nature communications
Carrega P,Loiacono F,Di Carlo E,Scaramuccia A,Mora M,Conte R,Benelli R,Spaggiari GM,Cantoni C,Campana S,Bonaccorsi I,Morandi B,Truini M,Mingari MC,Moretta L,Ferlazzo G
48-7349 was used in Flow cytometry/Cell sorting to investigate the role of the NCR(+) ILC-3 in non-small cell lung cancer.
Wed Sep 23 00:00:00 UTC 2015
Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma.
Science signaling
Kusne Y,Carrera-Silva EA,Perry AS,Rushing EJ,Mandell EK,Dietrich JD,Errasti AE,Gibbs D,Berens ME,Loftus JC,Hulme C,Yang W,Lu Z,Aldape K,Sanai N,Rothlin CV,Ghosh S
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Tue Aug 12 00:00:00 UTC 2014
Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma.
Science signaling
Kusne Y,Carrera-Silva EA,Perry AS,Rushing EJ,Mandell EK,Dietrich JD,Errasti AE,Gibbs D,Berens ME,Loftus JC,Hulme C,Yang W,Lu Z,Aldape K,Sanai N,Rothlin CV,Ghosh S
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Tue Aug 12 00:00:00 UTC 2014
Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma.
Science signaling
Kusne Y,Carrera-Silva EA,Perry AS,Rushing EJ,Mandell EK,Dietrich JD,Errasti AE,Gibbs D,Berens ME,Loftus JC,Hulme C,Yang W,Lu Z,Aldape K,Sanai N,Rothlin CV,Ghosh S
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Tue Aug 12 00:00:00 UTC 2014
Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma.
Science signaling
Kusne Y,Carrera-Silva EA,Perry AS,Rushing EJ,Mandell EK,Dietrich JD,Errasti AE,Gibbs D,Berens ME,Loftus JC,Hulme C,Yang W,Lu Z,Aldape K,Sanai N,Rothlin CV,Ghosh S
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Tue Aug 12 00:00:00 UTC 2014
Dendritic cells restore CD8+ T cell reactivity to autologous HIV-1.
Journal of virology
Smith KN,Mailliard RB,Larsen BB,Wong K,Gupta P,Mullins JI,Rinaldo CR
48-7349 was used in Flow cytometry/Cell sorting to demonstrate that antigen-presenting cells can be used to identify antigen-specific T cell reactivity in HIV-1 infection.
Mon Sep 01 00:00:00 UTC 2014
Functional avidity and IL-2/perforin production is linked to the emergence of mutations within HLA-B*5701-restricted epitopes and HIV-1 disease progression.
Journal of immunology (Baltimore, Md. : 1950)
Buggert M,Norström MM,Salemi M,Hecht FM,Karlsson AC
48-7349 was used in Flow cytometry/Cell sorting to distinguish whether specific functional characteristics of HLA-B*5701-restricted CD8+ T-cells influence the emergence of mutations in high-risk progressors versus low-risk progressors.
Thu May 15 00:00:00 UTC 2014
Transcriptional profile of tuberculosis antigen-specific T cells reveals novel multifunctional features.
Journal of immunology (Baltimore, Md. : 1950)
Arlehamn CL,Seumois G,Gerasimova A,Huang C,Fu Z,Yue X,Sette A,Vijayanand P,Peters B
48-7349 was used in Flow cytometry/Cell sorting to study the role of CD4(+) T cells in latent tuberculosis infection, showing that tuberculosis antigen-specific T cells have novel multifunctional features.
Mon Sep 15 00:00:00 UTC 2014
Cell-mediated immune responses to respiratory syncytial virus infection: magnitude, kinetics, and correlates with morbidity and age.
Human vaccines & immunotherapeutics
Geevarghese B,Weinberg A
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Mon Apr 25 00:00:00 UTC 2016
Mucosal immunization of lactating female rhesus monkeys with a transmitted/founder HIV-1 envelope induces strong Env-specific IgA antibody responses in breast milk.
Journal of virology
Fouda GG,Amos JD,Wilks AB,Pollara J,Ray CA,Chand A,Kunz EL,Liebl BE,Whitaker K,Carville A,Smith S,Colvin L,Pickup DJ,Staats HF,Overman G,Eutsey-Lloyd K,Parks R,Chen H,Labranche C,Barnett S,Tomaras GD,Ferrari G,Montefiori DC,Liao HX,Letvin NL,Haynes BF,Permar SR
48-7349-42 was used in Flow Cytometry to show that systemic MVA prime followed by either intranasal or systemic protein boosts can elicit strong humoral responses in breast milk and may be a useful strategy to interrupt postnatal HIV-1 transmission.
Sat Jun 01 00:00:00 UTC 2013
CD4⁺CD73⁺ T cells are associated with lower T-cell activation and C reactive protein levels and are depleted in HIV-1 infection regardless of viral suppression.
AIDS (London, England)
Schuler PJ,Macatangay BJ,Saze Z,Jackson EK,Riddler SA,Buchanan WG,Hilldorfer BB,Mellors JW,Whiteside TL,Rinaldo CR
48-7349 was used in Flow cytometry/Cell sorting to assess suppression of T-cell function by exogenous ADO and CD4+ CD73+ T cells.
Wed Jun 19 00:00:00 UTC 2013
Functional OCT4-specific CD4+ and CD8+ T cells in healthy controls and ovarian cancer patients.
Oncoimmunology
Di J,Massuger LF,Duiveman-de Boer T,Zusterzeel PL,Figdor CG,Torensma R
Published figure using TNF alpha monoclonal antibody (Product # 48-7349-42) in Flow Cytometry
Wed May 01 00:00:00 UTC 2013
Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity.
The Journal of clinical investigation
McMahan RH,Golden-Mason L,Nishimura MI,McMahon BJ,Kemper M,Allen TM,Gretch DR,Rosen HR
48-7349 was used in Flow cytometry/Cell sorting to indicate the coexpression of Tim-3 and PD-1 correlates with defective T-cell responses and may limit immune control of persistent pathogens.
Wed Dec 01 00:00:00 UTC 2010
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.jpg?time=20220826?time=20220826 "TNF alpha Antibody (48-7349-42) in Flow")
