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            • Primary Antibodies ›
            • Her-2 (ErbB2) Antibodies

            Invitrogen

            ErbB2 (HER-2) Monoclonal Antibody (6C2)

            Advanced Verification
            View all (284) Her-2 (ErbB2) antibodies
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            Catalog # MA5-15702
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            Price (USD)
            574.00
            100 µL
             
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            Cite ErbB2 (HER-2) Monoclonal Antibody (6C2)

            • Antibody Testing Data (6)
            • Advanced Verification (2)
            Application
            ErbB2 (HER-2) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Group 53 Created with Sketch.

            FIGURE: 1 / 8

            ErbB2 (HER-2) Antibody (MA5-15702) in IHC (P)

            Immunohistochemical analysis of paraffin-embedded galactophore tumour using ERBB2 monoclonal antibody (Product # MA5-15702) followed with DAB staining
            View Product

            ErbB2 (HER-2) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ErbB2 (HER-2) Antibody in Western Blot (WB)
            ErbB2 (HER-2) Antibody in Western Blot (WB)
            ErbB2 (HER-2) Antibody in Western Blot (WB)
            ErbB2 (HER-2) Antibody in Western Blot (WB)
            ErbB2 (HER-2) Antibody in Flow Cytometry (Flow)
            ErbB2 (HER-2) Antibody
            ErbB2 (HER-2) Antibody

            Product Details

            MA5-15702

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:500-1:2000
            -

            Immunohistochemistry (Paraffin) (IHC (P))

            1:200-1:1,000
            -

            Flow Cytometry (Flow)

            1:200-1:400
            -

            ELISA (ELISA)

            1:10,000
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Mouse / IgG1

            Class

            Monoclonal

            Type

            Antibody

            Clone

            6C2

            Immunogen

            Purified recombinant fragment of human ERBB2(aa750-987) expressed in E. Coli.
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            Conc. Not Determined

            Storage buffer

            ascites

            Contains

            0.03% sodium azide

            Storage conditions

            Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_10985801

            Product Specific Information

            MA5-15702 targets ERBB2 in indirect ELISA, FACS, IHC, and WB applications and shows reactivity with Human samples.

            The MA5-15702 immunogen is purified recombinant fragment of human ERBB2(aa750-987) expressed in E. Coli.

            MA5-15702 detects ERBB2 which has a predicted molecular weight of approximately 180kDa.

            Target Information

            ErbB2 (HER2) is a receptor tyrosine kinase that is overexpressed in some breast tumors. Herceptin, used in treatment of metastatic Her2-positive cancer, is monoclonal antibody targeting this kinase.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: c-erb B2/neu protein; CD antigen CD340; CD340; erb-b2; erbb 2; ErbB2 (pTyr1139); ErbB2 (pY1139); ErbB2 phospho Y1139; her 2; herstatin; human epidermal growth factor receptor 2; metas; Metastatic lymph node gene 19 protein; MLN 19; neuro/glioblastoma derived oncogene homolog; neuroblastoma/glioblastoma derived oncogene homolog; p185erbB2; phospho ErbB2; Proto-oncogene c-ErbB-2; Proto-oncogene Neu; Receptor tyrosine-protein kinase erbB-2; Tyrosine kinase-type cell surface receptor HER2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog

            View more View less

            Gene Aliases: CD340; ERBB2; HER-2; HER-2/neu; HER2; MLN 19; MLN19; NEU; NGL; TKR1

            View more View less

            UniProt ID: (Human) P04626

            View more View less

            Entrez Gene ID: (Human) 2064

            View more View less

            Function(s)

            RNA polymerase I core binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity receptor signaling protein tyrosine kinase activity transmembrane signaling receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding protein C-terminus binding growth factor binding protein phosphatase binding identical protein binding ErbB-3 class receptor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity protein heterodimerization activity protein dimerization activity transmembrane signal receptor

            Process(es)

            MAPK cascade positive regulation of protein phosphorylation transcription, DNA-templated protein phosphorylation signal transduction cell surface receptor signaling pathway enzyme linked receptor protein signaling pathway transmembrane receptor protein tyrosine kinase signaling pathway peripheral nervous system development heart development neuromuscular junction development motor neuron axon guidance cell proliferation phosphatidylinositol 3-kinase signaling regulation of phosphatidylinositol 3-kinase signaling peptidyl-tyrosine phosphorylation positive regulation of cell growth regulation of microtubule-based process negative regulation of immature T cell proliferation in thymus ERBB2 signaling pathway wound healing myelination positive regulation of MAP kinase activity positive regulation of GTPase activity positive regulation of translation regulation of angiogenesis positive regulation of cell adhesion positive regulation of transcription from RNA polymerase I promoter positive regulation of transcription from RNA polymerase III promoter protein autophosphorylation phosphatidylinositol phosphorylation phosphatidylinositol-mediated signaling oligodendrocyte differentiation positive regulation of epithelial cell proliferation regulation of ERK1 and ERK2 cascade cellular response to growth factor stimulus cellular response to epidermal growth factor stimulus positive regulation of protein targeting to membrane regulation of cell motility
            It has to be done as per old AB suggested Products section.
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            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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