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            • Primary Antibodies ›
            • DLL1 Antibodies

            Invitrogen

            DLL1 Monoclonal Antibody (251127)

            View all (25) DLL1 antibodies
            Datasheet
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            Catalog # MA5-23904
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            Price (USD)
            498.00
            100 µg
             
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            Cite DLL1 Monoclonal Antibody (251127)

            Product Details

            MA5-23904

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1 µg/mL
            -

            ELISA (ELISA)

            0.1-0.4 µg/mL (Detection), 2-8 µg/mL (Capture)
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Mouse / IgG2b

            Class

            Monoclonal

            Type

            Antibody

            Clone

            251127

            Immunogen

            Mouse myeloma cell line NS0-derived recombinant human DLL1 Ser22-Gly540
            View immunogen

            Conjugate

            Unconjugated

            Form

            Lyophilized

            Concentration

            0.5 mg/mL

            Purification

            Protein A/G

            Storage buffer

            PBS with 5% trehalose

            Contains

            No Preservative

            Storage conditions

            -20°C, Avoid Freeze/Thaw Cycles

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2610507

            Product Specific Information

            This antibody detects recombinant human DLL1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse DLL4 is observed.

            Reconstitute at 0.5 mg/mL in sterile PBS.

            Target Information

            Delta-like protein 1 (DLL1) is a transmembrane protein characterized by epidermal growth factor (EGF)-like repeats. It is a ligand for Notch receptor. It blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: Delta-like protein 1; Delta1; Drosophila Delta homolog 1; H-Delta-1; OTTHUMP00000017690

            View more View less

            Gene Aliases: Delta; DELTA1; DL1; DLL1; UNQ146/PRO172

            View more View less

            UniProt ID: (Human) O00548

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            Entrez Gene ID: (Human) 28514

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            Function(s)

            Notch binding calcium ion binding protein binding Tat protein binding scaffold protein binding

            Process(es)

            cell fate determination somitogenesis somite specification heart looping marginal zone B cell differentiation type B pancreatic cell development Notch signaling pathway Notch receptor processing determination of left/right symmetry compartment pattern specification regulation of blood pressure positive regulation of cell proliferation negative regulation of cell proliferation proximal/distal pattern formation astrocyte development regulation of somitogenesis spinal cord development cerebellar molecular layer formation cerebellar Purkinje cell layer structural organization hemopoiesis cell differentiation regulation of cell adhesion negative regulation of epithelial cell differentiation negative regulation of interleukin-10 production negative regulation of glial cell apoptotic process organ growth regulation of growth negative regulation of cell differentiation negative regulation of epidermal cell differentiation negative regulation of auditory receptor cell differentiation negative regulation of myeloid cell differentiation negative regulation of myoblast differentiation negative regulation of neuron differentiation positive regulation of Notch signaling pathway positive regulation of endocytosis positive regulation of transcription from RNA polymerase II promoter lateral inhibition skeletal muscle tissue growth regulation of skeletal muscle tissue growth positive regulation of skeletal muscle tissue growth neuron fate specification inner ear development regulation of neurogenesis regulation of cell division retina development in camera-type eye retina morphogenesis in camera-type eye Notch signaling pathway involved in arterial endothelial cell fate commitment left/right axis specification nephron development proximal tubule development loop of Henle development clathrin-mediated endocytosis endothelial tip cell fate specification neuronal stem cell population maintenance skin epidermis development regulation of vascular endothelial growth factor signaling pathway positive regulation of sprouting angiogenesis regulation of energy homeostasis
            It has to be done as per old AB suggested Products section.
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            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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