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Product Details
MA5-28764
Product Specifications
Species Reactivity
Chicken
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
CB3
Immunogen
Lymphocytes from the bursa of Fabricius of outbred chickens
Conjugate
Biotin
Form
Liquid
Concentration
0.5 mg/mL
Purification
purified
Storage buffer
PBS, pH 7.4, with proprietary stabilizer
Contains
<0.1% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2745723
Target Information
CD1.1 molecules, like MHC I and II, play an important role in the immune system by presenting lipid, glycolipid and lipopeptide antigen to T and NKT cells. The chicken CD1 gene is located in the chicken MHC B locus and has an important implication for the primordial MHC gene evolution. Two proteins have been identified - CD1.1 and CD1.2. Analysis of RNA from blood cells showed that both genes are expressed in Bu-1+ cells and CD8 alpha+ cells. CD1.2 is expressed in TCR gamma delta cells but is nearly undetectable in TCR alpha beta. The monoclonal antibody CB3 antibody can identify cells of the B cell lineage and recognizes CD1.1 but not CD1.2 on the surface of transfected mammalian cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: a polypeptide; CD1-2 antigen; CD1.2 antigen; CD1A antigen, a polypeptide; CD1a molecule; CD1c; chCD1-2; T-cell surface glycoprotein CD1A2 antigen
Gene Aliases: CD1.1; CD1.2; CD1A; CD1A2
Entrez Gene ID: (Chicken) 425802
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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