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Product Details
PA1-956
Applications
Tested Dilution
Publications
Product Specifications
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic Peptide: Y(24) S A T T A R Q E E V P(35) C
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2205073
Product Specific Information
PA1-956 detects decoy receptor 1 (DcR1) from human and rat tissues and cells.
PA1-956 has been successfully used in FACS and Western blot procedures. By Western blot, this antibody detects an ~30 kDa protein representing DcR1 from HEK293 cell lysate.
PA1-956 immunizing peptide corresponds to amino acid residues 24-35 of human DcR1. PA1-956 immunizing peptide (Cat. # PEP-047) is available for use in neutralization and control experiments.
Target Information
TRAIL-R3 (CD263) is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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