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Application
FIGURE: 1 / 6
TROY Antibody (PA5-116076) in ICC/IF
Immunocytochemistry analysis of TROY in A549 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-116076). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
Product Details
PA5-116076
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human TNFRSF19(Accession Q9NS68), corresponding to amino acid residues F304-D354.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2900710
Product Specific Information
Antibody detects endogenous levels of total TROY.
Target Information
Tumor necrosis factor receptor superfamily member 19, commonly known as TROY, is a gene located on chromosome 1p36.22 that encodes a member of the tumor necrosis factor receptor (TNFR) superfamily. TROY is expressed in the nervous system, skin, and various tissues, where it plays a role in regulating cell apoptosis, inflammation, and development. As a receptor, TROY interacts with ligands and other signaling molecules to modulate pathways involved in cell survival, differentiation, and immune responses. In the context of the nervous system, TROY has been implicated in axonal outgrowth and regeneration, particularly influencing signaling pathways related to neural development and repair. Additionally, TROY has been studied in cancer research due to its potential role in tumor growth and progression, making it a candidate for therapeutic targeting. Its involvement in diverse biological processes highlights its significance in maintaining cellular homeostasis and its potential as a therapeutic target in neurobiology and oncology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Toxicity and JNK inducer; TRADE; Tumor necrosis factor receptor superfamily member 19; tumor necrosis factor receptor superfamily, member 19
Gene Aliases: AL023044; AW123854; RGD1564996; TAJ; TAJ-ALPHA; TNFRSF19; TRADE; TROY; UNQ1888/PRO4333
UniProt ID: (Human) Q9NS68, (Mouse) Q9JLL3
Entrez Gene ID: (Human) 55504, (Rat) 290300, (Mouse) 29820
Performance Guarantee
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