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Product Details
PA5-22801
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to the N-terminus of human ACT.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11156812
Product Specific Information
Suggested positive control: antigen standard for TRAF3IP2 (transient overexpression lysate).
Target Information
This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Two alternative transcripts encoding different proteins have been identified. A third transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ACT1; Adapter protein CIKS; Connection to IKK and SAPK/JNK; E3 ubiquitin ligase TRAF3IP2; E3 ubiquitin-protein ligase CIKS; NFkB-activating protein ACT1; Nuclear factor NF-kappa-B activator 1; RP3-487J7.3; TRAF3-interacting protein 2
Gene Aliases: ACT1; AI429613; C6orf2; C6orf4; C6orf5; C6orf6; CANDF8; CIKS; PSORS13; TRAF3IP2
UniProt ID: (Human) O43734, (Mouse) Q8BH33
Entrez Gene ID: (Human) 10758, (Mouse) 103213
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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