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Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey (100%); Marmoset, Elephant (94%); Galago, Panda, Dog, Horse, Opossum, Platypus (88%); Mouse, Rat, Hamster, Bat, Bovine, Pig, Lizard (82%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Expression of this gene is induced by estrogen and the encoded protein has been characterized as a transmembrane protein. The encoded protein has been found in to correlate with survival in certain carcinomas (PMID: 21102415) and may be important for cellular response to stress (PMID: 21072319). Alternative splicing results in multiple transcript variants.
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Protein Aliases: Endosome/lysosome-associated apoptosis and autophagy regulator 1; Estrogen-induced gene 121 protein; maba1
Gene Aliases: EIG121; ELAPOR1; KIAA1324; UNQ2426/PRO4985
UniProt ID: (Human) Q6UXG2
Entrez Gene ID: (Human) 57535
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