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mGluR4 Antibody (PA5-47923) in IHC (P)
Immunohistochemical analysis of mGluR4 was detected in immersion fixed paraffin-embedded sections of human brainstem (medulla) using Sheep Anti-human mGluR4 Antigen Affinity-purified Polyclonal Antibody (Product # PA5-47923) at 1.7 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Sheep HRP-DAB (brown and counterstained with hematoxylin (blue). Specific staining was localized to endothelial cells i... View More
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.jpg?time=20220826?time=20220826 "mGluR4 Antibody (PA5-47923) in IHC (P)")
Product Details
PA5-47923
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CHO-derived recombinant human mGluR4 Lys33-Ser518
Conjugate
Unconjugated
Form
Lyophilized
Concentration
0.2 mg/mL
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2607818
Product Specific Information
In direct ELISAs, approximately 40% cross-reactivity with recombinant human (rh) mGluR7 and rhmGluR8 is observed, and less than 8% cross-reactivity with rhmGluR3 is observed.
Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
Target Information
The Metabotropic Glutamate Receptor mGluR4/GRM4 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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