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            Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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            • Primary Antibodies ›
            • Calbindin D28K Antibodies

            Invitrogen

            Calbindin D28K Polyclonal Antibody

            Advanced Verification
            View all (45) Calbindin D28K antibodies
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            Cite Calbindin D28K Polyclonal Antibody

            • Antibody Testing Data (2)
            • Advanced Verification (1)
            Application
            Calbindin D28K Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Group 53 Created with Sketch.

            FIGURE: 1 / 3

            Calbindin D28K Antibody (PA5-50366) in IHC (P)

            Immunohistochemical analysis of Calbindin D28K in paraffin embedded Human thyroid cancer tissue using Calbindin D28K Polyclonal Antibody (Product # PA5-50366) at a 1:60 dilution.
            View Product

            Calbindin D28K Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Calbindin D28K Antibody in Western Blot (WB)
            Calbindin D28K Antibody

            Product Details

            PA5-50366

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:500-1:2,000
            -

            Immunohistochemistry (Paraffin) (IHC (P))

            1:50-1:200
            -
            Product Specifications

            Species Reactivity

            Human, Mouse

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Fusion protein corresponding to a region derived from internal residues of human calbindin 1, 28kDa

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            3 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            PBS, pH 7.4, with 40% glycerol

            Contains

            0.05% sodium azide

            Storage conditions

            -20°C

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2635819

            Product Specific Information

            The antibody detects endogenous levels of total Calbindin D protein.

            Target Information

            Calbindin-D-28K (also termed vitamin D-dependent calcium-binding protein, or cholecalcin), is a highly conserved 28kDa calcium binding protein, with broad tissue distribution. It belongs, together with calmodulin, S-100, parvalbumin, troponin C and other proteins, to a family of low molecular weight calcium-binding proteins (CaBPs). These CaBPs have homologous primary structures, which contain conserved polypeptide folds of the EF-hand type for Ca2+ binding. Calbindin-D-28K is found predominantly in subpopulations of central and peripheral nervous system neurons, and in certain epithelial nervous system neurons, and in certain epithelial cells involved in Ca2+ transport such as distal tubular cells and cortical collecting tubules of the kidney, and in enteric neuroendocrine cells.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: Calbindin; calbindin 1, (28kD); calbindin 1, 28kDa; Calbindin D28; calbindin-28K; calbindin-D (28k); CalbindinD28K; D-28K; PCD-29; RTVL-H protein; Spot 35 protein; Vitamin D-dependent calcium-binding protein, avian-type

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            Gene Aliases: Brain-2; CAB27; CALB; Calb-1; CALB1; CB; D-28K

            View more View less

            UniProt ID: (Human) P05937, (Mouse) P12658

            View more View less

            Entrez Gene ID: (Human) 793, (Mouse) 12307

            View more View less

            Function(s)

            vitamin D binding calcium ion binding protein binding zinc ion binding metal ion binding calmodulin-related

            Process(es)

            short-term memory long-term memory locomotory behavior retina layer formation metanephric part of ureteric bud development regulation of synaptic plasticity regulation of cytosolic calcium ion concentration cellular response to organic substance metanephric collecting duct development metanephric distal convoluted tubule development metanephric connecting tubule development calcium ion homeostasis
            It has to be done as per old AB suggested Products section.
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            Performance Guarantee

            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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            We're here to help

            Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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