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Product Details
PA5-65796
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human KIAA1530. Recombinant protein control fragment (Product #RP-106469).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2663427
Product Specific Information
Immunogen sequence: RLSAFQIVEEL FVRSHQFRML VVSNFQEFLE LTLGTDPAQP LPPPREAAQR LRQATTRAVE GWNEKFGEAY KKLALGYHFL RHNKKVDFQD TNARSL
Highest antigen sequence identity to the following orthologs - mouse 81%, rat 82%.
Target Information
The protein encoded by KIAA1530 appears to be involved in ubiquitination and dephosphorylation of RNA polymerase II subunits that stall after UV irradiation. The encoded protein interacts with several members of the nucleotide excision repair complex, and is thought to be involved in the transcription-coupled nucleotide excision repair (TC-NER) pathway to help remove lesions in the DNA that block transcription. Defects in KIAA1530 can cause UV-sensitive syndrome 3. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: UV-stimulated scaffold protein A
Gene Aliases: KIAA1530; UVSS3; UVSSA
UniProt ID: (Human) Q2YD98
Entrez Gene ID: (Human) 57654
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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