Nucleoside phosphoramidites can be derived from natural or synthetic nucleosides and are used to synthesize oligonucleotides. A phosphoramidite is a phosphite diester monoamide with high reactivity towards nucleophiles that weak acids can catalyze.
iBu-rG CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with isobutyryl (iBu) base protection, for use in oligonucleotide synthesis.
Bz-dA CEP is a phosphoramidite containing 5' DMT and the nucleoside deoxyadenosine (dA) with Benzoyl (Bz) base protection, for use in oligonucleotide synthesis.
iPrPAC-rG CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with Isopropylphenoxyacetyl (iPrPAC) base protection, for use in oligonucleotide synthesis.
Bz-dC CEP is a phosphoramidite containing 5' DMT and the nucleoside deoxycytidine (dC) with Benzoyl (Bz) base protection, for use in oligonucleotide synthesis.
iPrPAC-rG CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with Isopropylphenoxyacetyl (iPrPAC) base protection, for use in oligonucleotide synthesis.
2'-OMe-G CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with 2'-O-methyl protection, for use in oligonucleotide synthesis.
2'-MOE-5mC CEP is a phosphoramidite containing 5' DMT and the nucleoside 5-methyl-cytidine (5mC) with 2'-O-methoxy-ethyl (MOE) protection, for use in oligonucleotide synthesis.
dU CEP is a phosphoramidite containing 5' DMT and the nucleoside deoxyuridine (dU) for use in oligonucleotide synthesis. The incorporation of a deoxyuridine base into a DNA sequence can be utilized to induce mutagenic effects.
DNA phosphoramidites are the building blocks for synthesis of DNA or DNA containing oligonucleotides. Each base has unique protecting groups designed specifically to protect the DNA during the chemical synthesis process, and produce the highest amount of full length product.
Bz-dC CEP is a phosphoramidite containing 5' DMT and the nucleoside deoxycytidine (dC) with Benzoyl (Bz) base protection, for use in oligonucleotide synthesis.
Thermo Scientific phosphoramidites with deoxyribonucleobases for synthesis of DNA oligos are built to meet the varying requirements of oligonucleotide manufacturers from the proof of concept of research and development (R&D) to the process development of therapeutic and diagnostic applications.
Structural phosphoramidites are nonstandard amidites used to synthesize modified oligonucleotides. Oligos with these specialty phosphoramidites are often used as primers, probes, or in structural studies.