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CES2 is a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance.
9030624L02Rik; 9130231C15Rik; ACH M1; Acylcarnitine hydrolase; acylcarnitine hydrolase M1; AI266984; Carboxylesterase 2; carboxylesterase 2 (intestine, liver); carboxylesterase 2A; carboxylesterase 2C; carboxylesterase 2E; carboxylesterase 5; carboxylesterase 6; carboxylesterase isoenzyme; carboxylesterase ML3; CE-2; CES 2; Ces2; CES-2; Ces2a; CES2A1; ces2A3; Ces2c; Ces2e; Ces2l; Ces5; Ces6; CESRL4; Cocaine esterase; hCE-2; ICE; intestinal carboxylesterase; liver carboxylesterase-2; methylumbelliferyl-acetate deacetylase 2; P iCE; PCE-2; Peroxisome proliferator-inducible acylcarnitine hydrolase; phenobarbital-inducible carboxylesterase (liver); pyrethroid hydrolase Ces2a; Pyrethroid hydrolase Ces2e
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