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The protein encoded by this gene acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osmoregulation in the proximal renal tubules. Defects in this gene are a cause of pentosuria. Two transcript variants encoding different isoforms have been found for this gene.
0610038K04Rik; 1810027P18Rik; carbonyl reductase; carbonyl reductase 2; carbonyl reductase II; DCR; Dcxr; diacetyl/L-xylulose reductase; dicarbonyl and L-xylulose reductase; dicarbonyl L-xylulose reductase; dicarbonyl/L-xylulose reductase; Glb; HCR2; HCRII; KI P34H; KID; KIDCR; Kidney dicarbonyl reductase; L-xylulose reductase; P34H; PNTSU; SDR20C1; Short chain dehydrogenase/reductase family 20C member 1; short chain dehydrogenase/reductase family 20C, member 1; sperm surface protein P34H; XR
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