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This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
AI747587; Gdc1; Gdc-1; glycerol 3-phosphate dehydrogenase; glycerol phosphate dehydrogenase 1, cytoplasmic adult; Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic; glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic; glycerol-3-phosphate dehydrogenase 1; glycerol-3-phosphate dehydrogenase 1 (soluble); glycerolphosphate dehydrogenase 1, cytoplasmic adult; glycerophosphate dehydrogenase; Gpd1; Gpd3; GPD-C; GPDH; GPDH-C; HTGTI; Kiaa4010; mKIAA4010
100 µL
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100 µg
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100 µL
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10 mg
1 mL
1 mg
2 mL
100 µL
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