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The structure of the MAS1 product indicates that it belongs to the class of receptors that are coupled to GTP-binding proteins and share a conserved structural motif, which is described as a 7-transmembrane segment following the prediction that these hydrophobic segments form membrane-spanning alpha-helices. The MAS1 protein may be a receptor that, when activated, modulates a critical component in a growth-regulating pathway to bring about oncogenic effects.
angiotensin-(1-7) receptor; c-mas; MAS; MAS proto-oncogene; MAS1; Mas-1; MAS1 oncogene; Mas1 proto-oncogene; MAS1 proto-oncogene, G protein-coupled receptor; Mas-related G protein-coupled receptor a; MGC119966; MGRA; Proto-oncogene Mas
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