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Phospholipase A2 catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2 enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets.
Group IB phospholipase A2; group IB secretory phospholipase A(2); MGC119834; MGC119835; phosphatidylcholine 2-acylhydrolase 1B; phospholipase; phospholipase A2; phospholipase A2 group IB; phospholipase A2, group 1B; phospholipase A2, group IB (pancreas); phospholipase A2, group IB, pancreas; phospholipase A2, major isoenzyme; PLA2; PLA2A; Pla2g1b; PLA2-Ib; PPLA2; sPLA(2)-IB; sPLA2IB; unnamed protein product
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