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This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome.
CHBL2; DCIP; Dendritic cell-derived IFNG-induced protein; deoxynucleoside triphosphate triphosphohydrolase SAMHD1; dNTPase; E330031J07Rik; EGK_02438; HDDC1; hSAMHD1; IFN-gamma induced; interferon-gamma-inducible protein Mg11; Mg11; Mg21; Monocyte protein 5; MOP5; MOP-5; mSAMHD1; RP1-132F21.1; SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1; SAM domain and HD domain 1; SAM domain and HD domain, 1; SAM domain and HD domain-containing protein 1; Samhd1; SBBI88
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