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This gene encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. Polymorphisms in the gene encoding this protein may be associated with fatigue and depression in patients suffering from hyperthyroidism. Alternative splicing results in multiple transcript variants.
BBB-specific anion transporter type 1; blood-brain barrier specific anion transporter; blood-brain barrier-specific anion transporter 1; Bsat1; OATP1; Oatp14; OATP-14; OATP1C1; Oatp2; OATPF; OATP-F; OATPRP5; OAT-RP-5; Organic anion transporter 2; organic anion transporter F; Organic anion transporter polypeptide-related protein 5; organic anion transporting polypeptide 14; organic anion-transporting polypeptide 14; Slc21a14; SLCO1C1; solute carrier family 21 (organic anion transporter), member 14; solute carrier family 21 member 14; Solute carrier organic anion transporter family member 1C1; solute carrier organic anion transporter family, member 1C1; thyroxine transporter
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