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Immunogen sequence: MTGHHGWGY GQDDGPSHWH KLYPIAQGDR QSPINIISSQ AVYSPSLQPL ELSYEACMSL SITNNGHSVQ VDFNDSDDRT VVTGGPLEGP YRLKQFHFHW GKKHDVGSEH TVDGKSFPSE LHLVHWNAKK YSTFGEAASA PDGLAVVGVF LETGDEHPSM NRLTDALYMV RFKGTKAQFS CFNPKCLLPA SRHYWTYPGS LTTPPLSESV TWIVLREPIC ISERQMGKFR SLLFTSEDDE RIHMVNNFRP PQPLKGRVVK ASFRA (1-264 aa encoded by BC033865)
Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary capillaries and proximal renal tubules. Its exact function is not known; however, it may have a role in inherited renal abnormalities of bicarbonate transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CA-VII; Carbonate dehydratase VII; Carbonic anhydrase 7; Carbonic anhydrase VII; carbonic dehydratase VII
Gene Aliases: AV343731; CA7; Car7; CAVII
UniProt ID: (Human) P43166, (Mouse) Q9ERQ8
Entrez Gene ID: (Human) 766, (Mouse) 12354, (Rat) 291819
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