Product References
Induction of lysosomal exocytosis and biogenesis via TRPML1 activation for the treatment of uranium-induced nephrotoxicity.
Nature communications
Zhong D,Wang R,Zhang H,Wang M,Zhang X,Chen H
14-1071-82 was used in Immunohistochemistry to demonstrate that the delayed administration of the specific TRPML1 agonist ML-SA1 significantly decreases U accumulation in the kidney, mitigates renal proximal tubular injury, increases apical exocytosis of lysosomes and reduces lysosomal membrane permeabilization (LMP) in renal PTECs of male mice with single-dose U poisoning or multiple-dose U exposure.
Thu Jul 06 00:00:00 EDT 2023
AQP4 Aggravates Cognitive Impairment in Sepsis-Associated Encephalopathy through Inhibiting Nav 1.6-Mediated Astrocyte Autophagy.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhu DD,Huang YL,Guo SY,Li N,Yang XW,Sui AR,Wu Q,Zhang Y,Kong Y,Li QF,Zhang T,Zheng WF,Li AP,Yu J,Ma TH,Li S
14-1071-82 was used in Western Blotting to investigate the effects of AQP4 associated with sepsis-associated encephalopathy (SAE) and reveal its underlying mechanism causing cognitive impairment.
Mon May 01 00:00:00 EDT 2023
A bacterial autotransporter impairs innate immune responses by targeting the transcription factor TFE3.
Nature communications
Ta A,Ricci-Azevedo R,Vasudevan SO,Wright SS,Kumari P,Havira MS,Surendran Nair M,Rathinam VA,Vanaja SK
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 14-1071-82) in Western Blot
Tue Apr 11 00:00:00 EDT 2023
P. gingivalis Infection Upregulates PD-L1 Expression on Dendritic Cells, Suppresses CD8+ T-cell Responses, and Aggravates Oral Cancer.
Cancer immunology research
Ren J,Han X,Lohner H,Hoyle RG,Li J,Liang S,Wang H
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 14-1071-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
Lipophagy-derived fatty acids undergo extracellular efflux via lysosomal exocytosis.
Autophagy
Cui W,Sathyanarayan A,Lopresti M,Aghajan M,Chen C,Mashek DG
14-1071-85 was used in Immunocytochemistry to show the pathway of lysosomal fusion to the plasma membrane is the primary route for the disposal of FAs derived from lipophagy, and that the efflux of FAs and their reuptake or subsequent extracellular trafficking to adjacent cells may play an important role in cell-to-cell lipid exchange and signaling.
Mon Mar 01 00:00:00 EST 2021
A small molecule binding HMGB1 inhibits caspase-11-mediated lethality in sepsis.
Cell death & disease
Wang X,Li Z,Bai Y,Zhang R,Meng R,Chen F,Wang H,Billiar TR,Xiao X,Lu B,Tang Y
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 14-1071-82) in Western Blot
Wed Apr 14 00:00:00 EDT 2021
Macrophage mediated recognition and clearance of Borrelia burgdorferi elicits MyD88-dependent and -independent phagosomal signals that contribute to phagocytosis and inflammation.
BMC immunology
Benjamin SJ,Hawley KL,Vera-Licona P,La Vake CJ,Cervantes JL,Ruan Y,Radolf JD,Salazar JC
14-1071-82 was used in Immunocytochemistry to show that MyD88 signaling enhances, but is not required, for bacterial uptake or phagosomal maturation and provide mechanistic insights into how MyD88-mediated phagosomal signaling enhances Bb uptake and clearance.
Mon May 17 00:00:00 EDT 2021
Macrophage mediated recognition and clearance of Borrelia burgdorferi elicits MyD88-dependent and -independent phagosomal signals that contribute to phagocytosis and inflammation.
BMC immunology
Benjamin SJ,Hawley KL,Vera-Licona P,La Vake CJ,Cervantes JL,Ruan Y,Radolf JD,Salazar JC
14-1071-82 was used in Immunocytochemistry to show that MyD88 signaling enhances, but is not required, for bacterial uptake or phagosomal maturation and provide mechanistic insights into how MyD88-mediated phagosomal signaling enhances Bb uptake and clearance.
Mon May 17 00:00:00 EDT 2021
An 8-Hydroxy-Quinoline Derivative Protects Against Lipopolysaccharide-Induced Lethality in Endotoxemia by Inhibiting HMGB1-Mediated Caspase-11 Signaling.
Frontiers in pharmacology
Wang X,Shi J,Li Z,Li L,Zhang R,Bai Y,Li J,Liang F,Tang Y
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 14-1071-82) in Western Blot
Tue Jun 08 00:00:00 EDT 2021
Synaptojanin1 deficiency upregulates basal autophagosome formation in astrocytes.
The Journal of biological chemistry
Pan PY,Zhu J,Rizvi A,Zhu X,Tanaka H,Dreyfus CF
14-1071-82 was used in Immunocytochemistry to demonstrate a novel mechanism for Synaptojanin1-related Parkinsonism involving astrocyte dysfunction.
Thu Jul 01 00:00:00 EDT 2021
Synaptojanin1 deficiency upregulates basal autophagosome formation in astrocytes.
The Journal of biological chemistry
Pan PY,Zhu J,Rizvi A,Zhu X,Tanaka H,Dreyfus CF
14-1071-82 was used in Immunocytochemistry to demonstrate a novel mechanism for Synaptojanin1-related Parkinsonism involving astrocyte dysfunction.
Thu Jul 01 00:00:00 EDT 2021
Microglial lysosome dysfunction contributes to white matter pathology and TDP-43 proteinopathy in GRN-associated FTD.
Cell reports
Wu Y,Shao W,Todd TW,Tong J,Yue M,Koga S,Castanedes-Casey M,Librero AL,Lee CW,Mackenzie IR,Dickson DW,Zhang YJ,Petrucelli L,Prudencio M
14-1071-82 was used in Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to imply that PGRN loss affects microglial activation and lysosomal function, resulting in the accumulation of myelin debris and contributing to TDP-43 pathology.
Tue Aug 24 00:00:00 EDT 2021
Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and Adaptive Immune Responses to Viral Infection.
Cell reports
Cham LB,Torrez Dulgeroff LB,Tal MC,Adomati T,Li F,Bhat H,Huang A,Lang PA,Moreno ME,Rivera JM,Galkina SA,Kosikova G,Stoddart CA,McCune JM,Myers LM,Weissman IL,Lang KS,Hasenkrug KJ
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 14-1071-82) in Flow Cytometry
Tue Apr 14 00:00:00 EDT 2020
Macropinocytosis drives T cell growth by sustaining the activation of mTORC1.
Nature communications
Charpentier JC,Chen D,Lapinski PE,Turner J,Grigorova I,Swanson JA,King PD
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 14-1071-82) in Immunofluorescence
Fri Jan 10 00:00:00 EST 2020
25(OH) D3 alleviate liver NK cytotoxicity in acute but not in chronic fibrosis model of BALB/c mice due to modulations in vitamin D receptor.
BMC gastroenterology
Salhab A,Amer J,Yinying L,Safadi R
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 14-1071-82) in Flow Cytometry
Fri Apr 10 00:00:00 EDT 2020
Foam Cell Induction Activates AMPK But Uncouples Its Regulation of Autophagy and Lysosomal Homeostasis.
International journal of molecular sciences
LeBlond ND,Nunes JRC,Smith TKT,O'Dwyer C,Robichaud S,Gadde S,Côté M,Kemp BE,Ouimet M,Fullerton MD
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 14-1071-82) in Immunocytochemistry
Fri Nov 27 00:00:00 EST 2020
Immunotherapy with engineered bacteria by targeting the STING pathway for anti-tumor immunity.
Nature communications
Leventhal DS,Sokolovska A,Li N,Plescia C,Kolodziej SA,Gallant CW,Christmas R,Gao JR,James MJ,Abin-Fuentes A,Momin M,Bergeron C,Fisher A,Miller PF,West KA,Lora JM
14-1071 was used in Immunocytochemistry-immunoflourescence to provide a roadmap for the development of future therapeutics and demonstrate the transformative potential of synthetic biology for the treatment of human disease when drug development criteria are incorporated into the design process for a living medicine.
Mon Jun 01 00:00:00 EDT 2020
Immunotherapy with engineered bacteria by targeting the STING pathway for anti-tumor immunity.
Nature communications
Leventhal DS,Sokolovska A,Li N,Plescia C,Kolodziej SA,Gallant CW,Christmas R,Gao JR,James MJ,Abin-Fuentes A,Momin M,Bergeron C,Fisher A,Miller PF,West KA,Lora JM
14-1071 was used in Immunocytochemistry-immunoflourescence to provide a roadmap for the development of future therapeutics and demonstrate the transformative potential of synthetic biology for the treatment of human disease when drug development criteria are incorporated into the design process for a living medicine.
Mon Jun 01 00:00:00 EDT 2020
The UPR preserves mature oligodendrocyte viability and function in adults by regulating autophagy of PLP.
JCI insight
Stone S,Wu S,Nave KA,Lin W
14-1071 was used in Immunohistochemistry-immunofluorescence to investigate the role of UPR for maintaining oligodendrocyte viability and function.
Thu Mar 12 00:00:00 EDT 2020
The complex of MCMV proteins and MHC class I evades NK cell control and drives the evolution of virus-specific activating Ly49 receptors.
The Journal of experimental medicine
Železnjak J,Lisnić VJ,Popović B,Lisnić B,Babić M,Halenius A,L'Hernault A,Roviš TL,Hengel H,Erhard F,Redwood AJ,Vidal SM,Dölken L,Krmpotić A,Jonjić S
14-1071 was used in Flow cytometry/Cell sorting to solve a long-standing conundrum of how MCMV avoids recognition by NK cells, unravels a fundamental new viral immune evasion mechanism, and demonstrates how this forced the evolution of virus-specific activating MHC I-restricted Ly49 receptors.
Mon Aug 05 00:00:00 EDT 2019
IFN-γ is a therapeutic target in paraneoplastic cerebellar degeneration.
JCI insight
Yshii L,Pignolet B,Mauré E,Pierau M,Brunner-Weinzierl M,Hartley O,Bauer J,Liblau R
14-1071 was used in Flow cytometry/Cell sorting to suggest that the production of IFN-γ by cerebellum-invading T cells plays a major role in Purkinje neuron death and can act as a target for the treatment of paraneoplastic cerebellar degeneration.
Thu Apr 04 00:00:00 EDT 2019
Critical role of post-transcriptional regulation for IFN-γ in tumor-infiltrating T cells.
Oncoimmunology
Salerno F,Guislain A,Freen-Van Heeren JJ,Nicolet BP,Young HA,Wolkers MC
14-1071 was used in Flow cytometry/Cell sorting to conclude that post-transcriptional mechanisms could be modulated to potentiate effective T cell therapies in cancer.
Tue Jan 12 00:00:00 EST 2021
Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion.
Nature communications
Sun C,Lan P,Han Q,Huang M,Zhang Z,Xu G,Song J,Wang J,Wei H,Zhang J,Sun R,Zhang C,Tian Z
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 14-1071-82) in Flow Cytometry
Wed Mar 28 00:00:00 EDT 2018
Mast Cells Respond to Candida albicans Infections and Modulate Macrophages Phagocytosis of the Fungus.
Frontiers in immunology
De Zuani M,Paolicelli G,Zelante T,Renga G,Romani L,Arzese A,Pucillo CEM,Frossi B
14-1071 was used in Immunocytochemistry-immunoflourescence to unravel the mechanisms of reciprocal influence between mucosal mast cells (MCs) and Candida albicans as commensal/opportunistic pathogen species in humans.
Thu Oct 03 00:00:00 EDT 2019
A TLR7 agonist enhances the antitumor efficacy of obinutuzumab in murine lymphoma models via NK cells and CD4 T cells.
Leukemia
Cheadle EJ,Lipowska-Bhalla G,Dovedi SJ,Fagnano E,Klein C,Honeychurch J,Illidge TM
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 14-1071-82) in Flow Cytometry
Sat Jul 01 00:00:00 EDT 2017
Polymicrobial sepsis impairs bystander recruitment of effector cells to infected skin despite optimal sensing and alarming function of skin resident memory CD8 T cells.
PLoS pathogens
Danahy DB,Anthony SM,Jensen IJ,Hartwig SM,Shan Q,Xue HH,Harty JT,Griffith TS,Badovinac VP
14-1071-82 was used in Flow Cytometry to directly examine the impact of sepsis on tissue resident memory CD8+ T cells in mice.
Fri Sep 01 00:00:00 EDT 2017
Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection.
The Journal of experimental medicine
Qi X,Man SM,Malireddi RK,Karki R,Lupfer C,Gurung P,Neale G,Guy CS,Lamkanfi M,Kanneganti TD
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 14-1071-82) in Western Blot
Mon Sep 19 00:00:00 EDT 2016
Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection.
The Journal of experimental medicine
Qi X,Man SM,Malireddi RK,Karki R,Lupfer C,Gurung P,Neale G,Guy CS,Lamkanfi M,Kanneganti TD
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 14-1071-82) in Western Blot
Mon Sep 19 00:00:00 EDT 2016
Trypanosoma brucei Co-opts NK Cells to Kill Splenic B2 B Cells.
PLoS pathogens
Frenkel D,Zhang F,Guirnalda P,Haynes C,Bockstal V,Radwanska M,Magez S,Black SJ
14-1071 was used in Flow cytometry/Cell sorting to investigate the mechanism by which natural killer cells in Trypanosoma brucei infected mice kill B cells, suppress humoral immunity and induce early mortality.
Fri Jul 01 00:00:00 EDT 2016
Differential Role of Hematopoietic and Nonhematopoietic Cell Types in the Regulation of NK Cell Tolerance and Responsiveness.
Journal of immunology (Baltimore, Md. : 1950)
Shifrin NT,Kissiov DU,Ardolino M,Joncker NT,Raulet DH
14107182 was used in flow cytometry to study the role of MCH I in natural killer cell tolerance and hyporesponsiveness
Tue Nov 15 00:00:00 EST 2016
NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.
Nature communications
Yang M,Chen S,Du J,He J,Wang Y,Li Z,Liu G,Peng W,Zeng X,Li D,Xu P,Guo W,Chang Z,Wang S,Tian Z,Dong Z
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 14-1071-82) in Flow Cytometry
Wed Sep 07 00:00:00 EDT 2016
Enhanced CD8 T cell responses through GITR-mediated costimulation resolve chronic viral infection.
PLoS pathogens
Pascutti MF,Geerman S,Slot E,van Gisbergen KP,Boon L,Arens R,van Lier RA,Wolkers MC,Nolte MA
14-1071 was used in Flow cytometry/Cell sorting to study resolution of chronic viral infection through GITR-mediated co-stimulation enhancing CD8 T cell responses.
Sun Mar 01 00:00:00 EST 2015
Unique Roles of TLR9- and MyD88-Dependent and -Independent Pathways in Adaptive Immune Responses to AAV-Mediated Gene Transfer.
Journal of innate immunity
Rogers GL,Suzuki M,Zolotukhin I,Markusic DM,Morel LM,Lee B,Ertl HC,Herzog RW
14-1071 was used in Flow cytometry/Cell sorting to investigate the functions of TLR2, TLR9 and the downstream signalling adaptor MyD88 in antibody and CD8+ T-cell responses.
Mon Jan 25 00:00:00 EST 2016
OX40- and CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence.
Journal of immunology (Baltimore, Md. : 1950)
Buchan S,Manzo T,Flutter B,Rogel A,Edwards N,Zhang L,Sivakumaran S,Ghorashian S,Carpenter B,Bennett C,Freeman GJ,Sykes M,Croft M,Al-Shamkhani A,Chakraverty R
14-1071 was used in Flow cytometry/Cell sorting to study how CD27-mediated co-stimulation can synergise with co-inhibitory checkpoint blockade to switch off molecular programs for quiescence in exhausted T cell populations.
Thu Jan 01 00:00:00 EST 2015
Histamine deficiency promotes accumulation of immunosuppressive immature myeloid cells and growth of murine gliomas.
Oncoimmunology
Ahn B,Kohanbash G,Ohkuri T,Kosaka A,Chen X,Ikeura M,Wang TC,Okada H
14-1071 was used in Flow cytometry/Cell sorting to investigate the role of HDC in the glioma microenvironment via maturation of myeloid cells and resulting activation of CD8(+) T cells.
Sun Nov 01 00:00:00 EDT 2015
Out-of-sequence signal 3 as a mechanism for virus-induced immune suppression of CD8 T cell responses.
PLoS pathogens
Urban SL,Welsh RM
14-1071 was used in Flow cytometry/Cell sorting to determine that type 1 interferon-pretreated CD8 T cells are desensitised to later delivery of this interferon.
Mon Sep 01 00:00:00 EDT 2014
CD8 T cells use IFN-γ to protect against the lethal effects of a respiratory poxvirus infection.
Journal of immunology (Baltimore, Md. : 1950)
Goulding J,Abboud G,Tahiliani V,Desai P,Hutchinson TE,Salek-Ardakani S
14-1071 was used in Flow cytometry/Cell sorting to reveal a previously unappreciated mechanism by which effector CD8 T cells afford protection against a highly virulent respiratory orthopox virus infection.
Sun Jun 01 00:00:00 EDT 2014
Tim-3 negatively mediates natural killer cell function in LPS-induced endotoxic shock.
PloS one
Hou H,Liu W,Wu S,Lu Y,Peng J,Zhu Y,Lu Y,Wang F,Sun Z
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 14-1071-82) in Flow Cytometry
Mon Jul 06 00:00:00 EDT 2015
Inflammatory neovascularization during graft-versus-host disease is regulated by αv integrin and miR-100.
Blood
Leonhardt F,Grundmann S,Behe M,Bluhm F,Dumont RA,Braun F,Fani M,Riesner K,Prinz G,Hechinger AK,Gerlach UV,Dierbach H,Penack O,Schmitt-Gräff A,Finke J,Weber WA,Zeiser R
14-1071-82 was used in Flow Cytometry to identify negative regulation of GvHD-related neovascularization by miR-100.
Thu Apr 25 00:00:00 EDT 2013
The risk of hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type 2.
Blood
Jessen B,Bode SF,Ammann S,Chakravorty S,Davies G,Diestelhorst J,Frei-Jones M,Gahl WA,Gochuico BR,Griese M,Griffiths G,Janka G,Klein C,Kögl T,Kurnik K,Lehmberg K,Maul-Pavicic A,Mumford AD,Pace D,Parvaneh N,Rezaei N,de Saint Basile G,Schmitt-Graeff A,Schwarz K,Karasu GT,Zieger B,Zur Stadt U,Aichele P,Ehl S
14-1071 was used in Flow cytometry/Cell sorting to elucidate the risk of predisposition to certain disorders of lymphocyte cytotoxicity.
Thu Apr 11 00:00:00 EDT 2013
Aged mice exhibit a severely diminished CD8 T cell response following respiratory syncytial virus infection.
Journal of virology
Fulton RB,Weiss KA,Pewe LL,Harty JT,Varga SM
14-1071 was used in Flow cytometry/Cell sorting to investigate the extent to which CD8 T cell response to respiratory syncytial virus is altered with age, showing that age severely diminishes response.
Sun Dec 01 00:00:00 EST 2013
Identification of Francisella novicida mutants that fail to induce prostaglandin E(2) synthesis by infected macrophages.
Frontiers in microbiology
Woolard MD,Barrigan LM,Fuller JR,Buntzman AS,Bryan J,Manoil C,Kawula TH,Frelinger JA
14-1071 was used in Immunocytochemistry-immunoflourescence to indicate that there is dissociation between intracellular growth and the ability of Francisella tularensis to induce prostaglandin E(2) synthesis.
Thu Feb 14 00:00:00 EST 2013
Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells.
Blood
Tewalt EF,Cohen JN,Rouhani SJ,Guidi CJ,Qiao H,Fahl SP,Conaway MR,Bender TP,Tung KS,Vella AT,Adler AJ,Chen L,Engelhard VH
14-1071 was used in Flow cytometry/Cell sorting to demonstrate that LECs mediate deletion only via programmed cell death-1 (PD-1) ligand 1.
Thu Dec 06 00:00:00 EST 2012
Eri1 regulates microRNA homeostasis and mouse lymphocyte development and antiviral function.
Blood
Thomas MF,Abdul-Wajid S,Panduro M,Babiarz JE,Rajaram M,Woodruff P,Lanier LL,Heissmeyer V,Ansel KM
14-1071 was used in Immunocytochemistry to show that mouse Eri1 regulates miRNA homeostasis in lymphocytes and is required for normal NK-cell development and antiviral immunity.
Thu Jul 05 00:00:00 EDT 2012
Liver production of sulfamidase reverses peripheral and ameliorates CNS pathology in mucopolysaccharidosis IIIA mice.
Molecular therapy : the journal of the American Society of Gene Therapy
Ruzo A,Garcia M,Ribera A,Villacampa P,Haurigot V,Marcó S,Ayuso E,Anguela XM,Roca C,Agudo J,Ramos D,Ruberte J,Bosch F
Wed Feb 01 00:00:00 EST 2012
Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection.
Mucosal immunology
Loebbermann J,Thornton H,Durant L,Sparwasser T,Webster KE,Sprent J,Culley FJ,Johansson C,Openshaw PJ
14-1071 was used in Flow cytometry/Cell sorting to study the various effects of the selective depletion of Tregs during acute RSV infection.
Thu Mar 01 00:00:00 EST 2012
A novel mechanism for the autonomous termination of pre-B cell receptor expression via induction of lysosome-associated protein transmembrane 5.
Molecular and cellular biology
Kawano Y,Ouchida R,Wang JY,Yoshikawa S,Yamamoto M,Kitamura D,Karasuyama H
14-1071 was used in Immunofluorescence to demonstrate that the pre-B cell receptor induces downmodulation of its own expression through induction of LAPTM5.
Thu Nov 01 00:00:00 EDT 2012
Subtle differences in CTL cytotoxicity determine susceptibility to hemophagocytic lymphohistiocytosis in mice and humans with Chediak-Higashi syndrome.
Blood
Jessen B,Maul-Pavicic A,Ufheil H,Vraetz T,Enders A,Lehmberg K,Längler A,Gross-Wieltsch U,Bay A,Kaya Z,Bryceson YT,Koscielniak E,Badawy S,Davies G,Hufnagel M,Schmitt-Graeff A,Aichele P,Zur Stadt U,Schwarz K,Ehl S
14-1071 was used in Flow cytometry/Cell sorting to suggest that differences in cytotoxic capacity of CTLs may indicate the risk of Chediak-Higashi syndrome patients to develop hemophagocytic lymphohistiocytosis.
Thu Oct 27 00:00:00 EDT 2011
Characteristic features of intracellular pathogenic Leptospira in infected murine macrophages.
Cellular microbiology
Toma C,Okura N,Takayama C,Suzuki T
14-1071 was used in Immunohistochemistry to compare the intracellular trafficking undertaken by non-pathogenic Leptospira biflexa and pathogenic L. interrogans in mouse bone marrow-derived macrophages.
Tue Nov 01 00:00:00 EDT 2011
Requirement for invariant chain in macrophages for Mycobacterium tuberculosis replication and CD1d antigen presentation.
Infection and immunity
Sillé FC,Martin C,Jayaraman P,Rothchild A,Fortune S,Besra GS,Behar SM,Boes M
14-1071 was used in Immunofluorescence to demonstrate that the host factor Ii is crucial for invariant natural killer T-cell recognition of infected macrophages.
Mon Aug 01 00:00:00 EDT 2011
Laser-induced endothelial cell activation supports fibrin formation.
Blood
Atkinson BT,Jasuja R,Chen VM,Nandivada P,Furie B,Furie BC
14-1071 was used in Immunocytochemistry-immunoflourescence to monitor calcium mobilisation to assess activation of the laser-targeted endothelial cells.
Thu Nov 25 00:00:00 EST 2010
Separation of graft-versus-host disease from graft-versus-leukemia responses by targeting CC-chemokine receptor 7 on donor T cells.
Blood
Coghill JM,Carlson MJ,Panoskaltsis-Mortari A,West ML,Burgents JE,Blazar BR,Serody JS
14-1071 was used in Flow cytometry/Cell sorting to investigate the role of MHC disparity between donor and recipient, in the attenuated graft-versus-host disease responses of murine T cells lacking CCR7.
Thu Jun 10 00:00:00 EDT 2010
MHC class I-deficient natural killer cells acquire a licensed phenotype after transfer into an MHC class I-sufficient environment.
The Journal of experimental medicine
Elliott JM,Wahle JA,Yokoyama WM
14-1071 was used in Flow cytometry/Cell sorting to investigate whether licensing is developmentally determined in the bone marrow, showing that MHC class I ligands are not absolutely required for licensing.
Mon Sep 27 00:00:00 EDT 2010
Naive tumor-specific CD4(+) T cells differentiated in vivo eradicate established melanoma.
The Journal of experimental medicine
Xie Y,Akpinarli A,Maris C,Hipkiss EL,Lane M,Kwon EK,Muranski P,Restifo NP,Antony PA
14-1071 was used in Flow cytometry/Cell sorting to study the regression of tumours due to naive tumor-specific CD4(+) T cell differentiation.
Mon Mar 15 00:00:00 EDT 2010
Chronic cigarette smoke exposure primes NK cell activation in a mouse model of chronic obstructive pulmonary disease.
Journal of immunology (Baltimore, Md. : 1950)
Motz GT,Eppert BL,Wortham BW,Amos-Kroohs RM,Flury JL,Wesselkamper SC,Borchers MT
14-1071 was used in Flow cytometry/Cell sorting to demonstrate an entirely novel mechanism of NK cell activation resulting from chronic cigarette smoke exposure.
Thu Apr 15 00:00:00 EDT 2010
Helicobacter pylori impairs murine dendritic cell responses to infection.
PloS one
Wang YH,Gorvel JP,Chu YT,Wu JJ,Lei HY
14-1071 was used in Immunofluorescence to show that H. pylori can infect and replicate in BMDCs, which has implications in the discussions around the biological life cycle of H. pylori in the host.
Thu May 27 00:00:00 EDT 2010
Actin and phosphoinositide recruitment to fully formed Candida albicans phagosomes in mouse macrophages.
Journal of innate immunity
Heinsbroek SE,Kamen LA,Taylor PR,Brown GD,Swanson J,Gordon S
14-1071 was used in Immunohistochemistry to show that polymerization of actin on the C. albicans phagosome was independent of PI3K.
Wed Jul 21 00:00:00 EDT 2010
Gpnmb is a melanosome-associated glycoprotein that contributes to melanocyte/keratinocyte adhesion in a RGD-dependent fashion.
Experimental dermatology
Tomihari M,Hwang SH,Chung JS,Cruz PD,Ariizumi K
14-1071 was used in Immunocytochemistry to demonstrate that Gpnmb is a melanosome-associated glycoprotein that contributes to the adhesion of melanocytes with keratinocytes.
Wed Jul 01 00:00:00 EDT 2009
Gpnmb is a melanosome-associated glycoprotein that contributes to melanocyte/keratinocyte adhesion in a RGD-dependent fashion.
Experimental dermatology
Tomihari M,Hwang SH,Chung JS,Cruz PD,Ariizumi K
14-1071 was used in Immunocytochemistry to demonstrate that Gpnmb is a melanosome-associated glycoprotein that contributes to the adhesion of melanocytes with keratinocytes.
Wed Jul 01 00:00:00 EDT 2009
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.
Nature immunology
Halle A,Hornung V,Petzold GC,Stewart CR,Monks BG,Reinheckel T,Fitzgerald KA,Latz E,Moore KJ,Golenbock DT
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 14-1071-82) in Immunofluorescence
Fri Aug 01 00:00:00 EDT 2008
