Product References
The Potential of Dendritic-Cell-Based Vaccines to Modulate Type 3 Innate Lymphoid Cell Populations.
International journal of molecular sciences
Chan L,Mehrani Y,Minott JA,Bridle BW,Karimi K
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Thu Jan 26 00:00:00 EST 2023
SARS-CoV-2 spike protein promotes inflammatory cytokine activation and aggravates rheumatoid arthritis.
Cell communication and signaling : CCS
Lee AR,Woo JS,Lee SY,Lee YS,Jung J,Lee CR,Park SH,Cho ML
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Thu Mar 02 00:00:00 EST 2023
EC-18 prevents autoimmune arthritis by suppressing inflammatory cytokines and osteoclastogenesis.
Arthritis research & therapy
Park JS,Yang SC,Jeong HY,Lee SY,Ryu JG,Choi JW,Kang HY,Kim SM,Hwang SH,Cho ML,Park SH
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Thu Nov 17 00:00:00 EST 2022
Free Fatty Acid Receptor 4 (FFA4) Activation Ameliorates Imiquimod-Induced Psoriasis in Mice.
International journal of molecular sciences
Son SE,Koh JM,Im DS
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Tue Apr 19 00:00:00 EDT 2022
Transcription factor RORα enforces stability of the Th17 cell effector program by binding to a Rorc cis-regulatory element.
Immunity
Hall JA,Pokrovskii M,Kroehling L,Kim BR,Kim SY,Wu L,Lee JY,Littman DR
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Tue Nov 08 00:00:00 EST 2022
Genetic manipulation of the human gut bacterium Eggerthella lenta reveals a widespread family of transcriptional regulators.
Nature communications
Dong X,Guthrie BGH,Alexander M,Noecker C,Ramirez L,Glasser NR,Turnbaugh PJ,Balskus EP
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Fri Dec 09 00:00:00 EST 2022
Lactate induces metabolic and epigenetic reprogramming of pro-inflammatory Th17 cells.
EMBO reports
Lopez Krol A,Nehring HP,Krause FF,Wempe A,Raifer H,Nist A,Stiewe T,Bertrams W,Schmeck B,Luu M,Leister H,Chung HR,Bauer UM,Adhikary T,Visekruna A
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Tue Dec 06 00:00:00 EST 2022
Lentinan alleviates arsenic-induced hepatotoxicity in mice via downregulation of OX40/IL-17A and activation of Nrf2 signaling.
BMC pharmacology & toxicology
Yang Y,Song S,Nie Y,Chen R,Chen P
45-7177-82 was used in Flow Cytometry to demonstrate that lentinan antagonizes SA-induced hepatotoxicity in mice, may be involved in the downregulations of pro-inflammatory OX40 or IL-17A and the activation of anti-oxidative Nrf2, NQO1 signals.
Tue Mar 22 00:00:00 EDT 2022
Trichinella spiralis Paramyosin Induces Colonic Regulatory T Cells to Mitigate Inflammatory Bowel Disease.
Frontiers in cell and developmental biology
Hao C,Wang W,Zhan B,Wang Z,Huang J,Sun X,Zhu X
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Tue Aug 03 00:00:00 EDT 2021
Prevention of EAE by tolerogenic vaccination with PEGylated antigenic peptides.
Therapeutic advances in chronic disease
Pfeil J,Simonetti M,Lauer U,von Thülen B,Durek P,Poulsen C,Pawlowska J,Kröger M,Krähmer R,Leenders F,Hoffmann U,Hamann A
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Tue Nov 07 00:00:00 EST 2023
Preliminary analysis of immunoregulatory mechanism of hyperhomocysteinemia-induced brain injury in Wistar-Kyoto rats.
Experimental and therapeutic medicine
Zhang Y,Wang L,Li X,Geng J
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
In Vivo Induction of Regulatory T Cells Via CTLA-4 Signaling Peptide to Control Autoimmune Encephalomyelitis and Prevent Disease Relapse.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Kim GR,Kim WJ,Lim S,Lee HG,Koo JH,Nam KH,Kim SM,Park SD,Choi JM
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Thu Jul 01 00:00:00 EDT 2021
G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators.
Nature communications
Gurusamy M,Tischner D,Shao J,Klatt S,Zukunft S,Bonnavion R,Günther S,Siebenbrodt K,Kestner RI,Kuhlmann T,Fleming I,Offermanns S,Wettschureck N
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Tue Nov 23 00:00:00 EST 2021
The RNase MCPIP3 promotes skin inflammation by orchestrating myeloid cytokine response.
Nature communications
Liu B,Huang J,Ashraf A,Rahaman O,Lou J,Wang L,Cai P,Wen J,Anwaar S,Liu X,Ni H,Ganguly D,Zhao J,Yang CY
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Fri Jul 02 00:00:00 EDT 2021
Prunella vulgaris L. Attenuates Experimental Autoimmune Thyroiditis by Inhibiting HMGB1/TLR9 Signaling.
Drug design, development and therapy
Guo Q,Qu H,Zhang H,Zhong X
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Tue Feb 22 00:00:00 EST 2022
Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism.
Nature communications
Fu Z,Dean JW,Xiong L,Dougherty MW,Oliff KN,Chen ZE,Jobin C,Garrett TJ,Zhou L
45-7177-82 was used in Flow Cytometry to show that IL-22, a cytokine produced by RORγt+ lymphocytes inhibits IL-13-induced tuft cell differentiation in vitro, and suppresses the tuft cell-type 2 immune circuit and small intestine lengthening in vivo, highlighting its key role in gut tissue remodeling.
Thu Jul 22 00:00:00 EDT 2021
In Vivo Antigen Expression Regulates CD4 T Cell Differentiation and Vaccine Efficacy against Mycobacterium tuberculosis Infection.
mBio
Clemmensen HS,Dube JY,McIntosh F,Rosenkrands I,Jungersen G,Aagaard C,Andersen P,Behr MA,Mortensen R
45-7177-82 was used in Flow cytometry/Cell sorting to demonstrate that immunization with such antigens can counteract this phenomenon by maintaining antigen-specific T cells in a state of low differentiation.
Tue Apr 20 00:00:00 EDT 2021
Retinoic Acid Induces Functionally Suppressive Foxp3+RORγt+ T Cells In Vitro.
Frontiers in immunology
Martínez-Blanco M,Lozano-Ojalvo D,Pérez-Rodríguez L,Benedé S,Molina E,López-Fandiño R
45-7177-82 was used in Flow Cytometry to show that under the influence of IL-2 and TGF-β, suppressive Foxp3+RORγt+ T cells that express and secrete IL-17 can be produced in vitro and RA further contributes to stabilize this phenotype.
Thu Oct 21 00:00:00 EDT 2021
Analysis of T cells in mouse lymphoid tissue and blood with flow cytometry.
STAR protocols
Skordos I,Demeyer A,Beyaert R
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Fri Mar 19 00:00:00 EDT 2021
Analysis of T cells in mouse lymphoid tissue and blood with flow cytometry.
STAR protocols
Skordos I,Demeyer A,Beyaert R
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Fri Mar 19 00:00:00 EDT 2021
Intestinal barrier dysfunction plays an integral role in arthritis pathology and can be targeted to ameliorate disease.
Med (New York, N.Y.)
Matei DE,Menon M,Alber DG,Smith AM,Nedjat-Shokouhi B,Fasano A,Magill L,Duhlin A,Bitoun S,Gleizes A,Hacein-Bey-Abina S,Manson JJ,Rosser EC,Klein N,Blair PA,Mauri C
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Fri Jul 09 00:00:00 EDT 2021
Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity.
Cell metabolism
Angiari S,Runtsch MC,Sutton CE,Palsson-McDermott EM,Kelly B,Rana N,Kane H,Papadopoulou G,Pearce EL,Mills KHG,O'Neill LAJ
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Tue Feb 04 00:00:00 EST 2020
GRIM-19 Ameliorates Multiple Sclerosis in a Mouse Model of Experimental Autoimmune Encephalomyelitis with Reciprocal Regulation of IFNγ/Th1 and IL-17A/Th17 Cells.
Immune network
Moon J,Lee SH,Lee SY,Ryu J,Jhun J,Choi J,Kim GN,Roh S,Park SH,Cho ML
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Novel, Non-Gene-Destructive Knock-In Reporter Mice Refute the Concept of Monoallelic Gata3 Expression.
Journal of immunology (Baltimore, Md. : 1950)
Rao TN,Kumar S,Pulikkottil AJ,Oliveri F,Hendriks RW,Beckel F,Fehling HJ
45-7177 was used in Flow cytometry/Cell sorting to show that GATIR mice faithfully reflect endogenous Gata3 expression without disturbing the development of GATA-3-dependent lymphoid cell populations.
Fri May 01 00:00:00 EDT 2020
IL-13 Ameliorates Neuroinflammation and Promotes Functional Recovery after Traumatic Brain Injury.
Journal of immunology (Baltimore, Md. : 1950)
Miao W,Zhao Y,Huang Y,Chen D,Luo C,Su W,Gao Y
45-7177 was used in Flow cytometry/Cell sorting to demonstrate that IL-13 treatment improved neurologic outcomes after Traumatic Brain Injury through adjusting microglia/macrophage phenotypes and inhibiting inflammatory responses.
Sun Mar 15 00:00:00 EDT 2020
IL-17A-producing T cells exacerbate fine particulate matter-induced lung inflammation and fibrosis by inhibiting PI3K/Akt/mTOR-mediated autophagy.
Journal of cellular and molecular medicine
Cong LH,Li T,Wang H,Wu YN,Wang SP,Zhao YY,Zhang GQ,Duan J
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2020
Exploring the Mechanism on the Medullary Visceral Zone Inhibiting the Cholinergic Anti-inflammatory Pathway Induced by Sepsis.
Mediators of inflammation
Li HB,Zhou Y,Zhao AH,Guo LL
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
FUT1 deficiency elicits immune dysregulation and corneal opacity in steady state and under stress.
Cell death & disease
Kim KW,Ryu JS,Ko JH,Kim JY,Kim HJ,Lee HJ,Oh JH,Chung JH,Oh JY
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Fri Apr 24 00:00:00 EDT 2020
Mitochondrial Pyruvate Carrier 1 Promotes Peripheral T Cell Homeostasis through Metabolic Regulation of Thymic Development.
Cell reports
Ramstead AG,Wallace JA,Lee SH,Bauer KM,Tang WW,Ekiz HA,Lane TE,Cluntun AA,Bettini ML,Round JL,Rutter J,O'Connell RM
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Tue Mar 03 00:00:00 EST 2020
UCP3 reciprocally controls CD4+ Th17 and Treg cell differentiation.
PloS one
O'Connor EB,Muñoz-Wolf N,Leon G,Lavelle EC,Mills KHG,Walsh PT,Porter RK
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Thu Jan 07 00:00:00 EST 2021
M1 Macrophage Derived Exosomes Aggravate Experimental Autoimmune Neuritis via Modulating Th1 Response.
Frontiers in immunology
Du T,Yang CL,Ge MR,Liu Y,Zhang P,Li H,Li XL,Li T,Liu YD,Dou YC,Yang B,Duan RS
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Tue Apr 13 00:00:00 EDT 2021
Parenteral vaccination protects against transcervical infection with Chlamydia trachomatis and generate tissue-resident T cells post-challenge.
NPJ vaccines
Nguyen NDNT,Olsen AW,Lorenzen E,Andersen P,Hvid M,Follmann F,Dietrich J
45-7177-82 was used in Flow Cytometry to study the protective efficacy of a parenteral Chlamydia vaccine, formulated in the Th1/Th17 T cell-inducing adjuvant CAF01.
Thu Aug 12 00:00:00 EDT 2021
Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses.
Scientific reports
Hrdý J,Alard J,Couturier-Maillard A,Boulard O,Boutillier D,Delacre M,Lapadatescu C,Cesaro A,Blanc P,Pot B,Ryffel B,Chamaillard M,Grangette C
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Tue Mar 24 00:00:00 EDT 2020
Rhein modulates host purine metabolism in intestine through gut microbiota and ameliorates experimental colitis.
Theranostics
Wu J,Wei Z,Cheng P,Qian C,Xu F,Yang Y,Wang A,Chen W,Sun Z,Lu Y
45-7177 was used in Flow cytometry/Cell sorting to investigate the effect of rhein on colitis and studied its possible mechanisms.
Mon May 31 00:00:00 EDT 2021
Alternative ZAP70-p38 signals prime a classical p38 pathway through LAT and SOS to support regulatory T cell differentiation.
Science signaling
Jun JE,Kulhanek KR,Chen H,Chakraborty A,Roose JP
45-7177 was used in Flow cytometry/Cell sorting to investigate how both classical and alternative p38 pathways contribute to T cell activation and therefore the immune balance.
Tue Jul 23 00:00:00 EDT 2019
Neutralization of interleukin-17A alleviates burn-induced intestinal barrier disruption via reducing pro-inflammatory cytokines in a mouse model.
Burns & trauma
Song Y,Li Y,Xiao Y,Hu W,Wang X,Wang P,Zhang X,Yang J,Huang Y,He W,Huang C
45-7177 was used in Flow cytometry/Cell sorting to investigate the effect of IL-17A and associated pro-inflammatory cytokines that were deeply involved in the pathogenesis of burn-induced intestinal inflammatory injury, and to determine the early source of IL-17A in the intestine.
Tue Apr 12 00:00:00 EDT 2022
IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis.
Journal of immunology (Baltimore, Md. : 1950)
Lindahl H,Guerreiro-Cacais AO,Bedri SK,Linnerbauer M,Lindén M,Abdelmagid N,Tandre K,Hollins C,Irving L,Glover C,Jones C,Alfredsson L,Rönnblom L,Kockum I,Khademi M,Jagodic M,Olsson T
45-7177-82 was used in Flow Cytometry to study the genetic risk variant rs17066096 and the candidate gene that encodes IL-22 binding protein (IL-22BP).
Thu Aug 15 00:00:00 EDT 2019
Lactobacillus rhamnosus GG attenuates tenofovir disoproxil fumarate-induced bone loss in male mice via gut-microbiota-dependent anti-inflammation.
Therapeutic advances in chronic disease
Liu H,Gu R,Li W,Zhou W,Cong Z,Xue J,Liu Y,Wei Q,Zhou Y
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Sat Apr 09 00:00:00 EDT 2022
Interleukin 10 Gene-Modified Bone Marrow-Derived Dendritic Cells Attenuate Liver Fibrosis in Mice by Inducing Regulatory T Cells and Inhibiting the TGF-β/Smad Signaling Pathway.
Mediators of inflammation
Xu Y,Tang X,Yang M,Zhang S,Li S,Chen Y,Liu M,Guo Y,Lu M
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Tue Jun 11 00:00:00 EDT 2019
IL-31 plays dual roles in lung inflammation in an OVA-induced murine asthma model.
Biology open
Huang J,Yue H,Jiang T,Gao J,Shi Y,Shi B,Wu X,Gou X
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Tue Jan 15 00:00:00 EST 2019
CNS lymphatic drainage and neuroinflammation are regulated by meningeal lymphatic vasculature.
Nature neuroscience
Louveau A,Herz J,Alme MN,Salvador AF,Dong MQ,Viar KE,Herod SG,Knopp J,Setliff JC,Lupi AL,Da Mesquita S,Frost EL,Gaultier A,Harris TH,Cao R,Hu S,Lukens JR,Smirnov I,Overall CC,Oliver G,Kipnis J
45-7177 was used in Flow cytometry/Cell sorting to demonstrate that meningeal lymphatics fulfill two critical criteria: they assist in the drainage of cerebrospinal fluid components and enable immune cells to enter draining lymph nodes in a CCR7-dependent manner.
Mon Oct 01 00:00:00 EDT 2018
Bryostatin-1 alleviates experimental multiple sclerosis.
Proceedings of the National Academy of Sciences of the United States of America
Kornberg MD,Smith MD,Shirazi HA,Calabresi PA,Snyder SH,Kim PM
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Tue Feb 27 00:00:00 EST 2018
RKIP mediates autoimmune inflammation by positively regulating IL-17R signaling.
EMBO reports
Lin W,Wang N,Zhou K,Su F,Jiang Y,Shou J,Liu H,Ma C,Qian Y,Wang K,Wang X
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Fri Jun 01 00:00:00 EDT 2018
MicroRNA-126 deficiency enhanced the activation and function of CD4+ T cells by elevating IRS-1 pathway.
Clinical and experimental immunology
Chu F,Hu Y,Zhou Y,Guo M,Lu J,Zheng W,Xu H,Zhao J,Xu L
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Thu Feb 01 00:00:00 EST 2018
Combined treatment with simvastatin and rapamycin attenuates cardiac allograft rejection through the regulation of T helper 17 and regulatory T cells.
Experimental and therapeutic medicine
Liu Y,Sun L,Chen W,Chuai J,Shang Y,Zhang D,Fu B,Tian H,Jiang S
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Thu Feb 01 00:00:00 EST 2018
Baicalin Downregulates RLRs Signaling Pathway to Control Influenza A Virus Infection and Improve the Prognosis.
Evidence-based complementary and alternative medicine : eCAM
Pang P,Zheng K,Wu S,Xu H,Deng L,Shi Y,Chen X
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation.
eLife
Lian G,Gnanaprakasam JR,Wang T,Wu R,Chen X,Liu L,Shen Y,Yang M,Yang J,Chen Y,Vasiliou V,Cassel TA,Green DR,Liu Y,Fan TW,Wang R
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Mon Sep 10 00:00:00 EDT 2018
Vibrio vulnificus RtxA Is a Major Factor Driving Inflammatory T Helper Type 17 Cell Responses in vitro and in vivo.
Frontiers in immunology
Lee A,Kim MS,Cho D,Jang KK,Choi SH,Kim TS
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Mon Sep 30 00:00:00 EDT 2019
ITGB4 deficiency in bronchial epithelial cells directs airway inflammation and bipolar disorder-related behavior.
Journal of neuroinflammation
Han L,Wang L,Tang S,Yuan L,Wu S,Du X,Xiang Y,Qu X,Liu H,Luo H,Qin X,Liu C
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Fri Aug 31 00:00:00 EDT 2018
Epigenetic control of IL-23 expression in keratinocytes is important for chronic skin inflammation.
Nature communications
Li H,Yao Q,Mariscal AG,Wu X,Hülse J,Pedersen E,Helin K,Waisman A,Vinkel C,Thomsen SF,Avgustinova A,Benitah SA,Lovato P,Norsgaard H,Mortensen MS,Veng L,Rozell B,Brakebusch C
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Thu Apr 12 00:00:00 EDT 2018
Nicotinamide adenine dinucleotide phosphate (reduced) oxidase 2 modulates inflammatory vigor during nonalcoholic fatty liver disease progression in mice.
Hepatology communications
Mukherjee R,Moreno-Fernandez ME,Giles DA,Cappelletti M,Stankiewicz TE,Chan CC,Divanovic S
45-7177 was used in Flow cytometry/Cell sorting to demonstrate a crucial role of the NOX2-ROS axis in immune cell effector function and polarization and consequent NAFLD progression in obesity.
Tue May 01 00:00:00 EDT 2018
Lentivirus-mediated overexpression of suppressor of cytokine signaling-3 reduces neutrophilic airway inflammation by suppressing T-helper 17 responses in mice with chronic Pseudomonas aeruginosa lung infections.
International journal of molecular medicine
Ding FM,Zhang XY,Chen YQ,Liao RM,Xie GG,Zhang PY,Shao P,Zhang M
45-7177-82 was used in Flow cytometry/Cell sorting to reveal that Lentivirus-mediated overexpression of SOCS3 ameliorates neutrophilic airway inflammation by inhibiting pulmonary Th17 responses in mice with chronic Pseudomonas aeruginosa (PA) lung infections.
Sun Apr 01 00:00:00 EDT 2018
Peroxisomal β-oxidation regulates whole body metabolism, inflammatory vigor, and pathogenesis of nonalcoholic fatty liver disease.
JCI insight
Moreno-Fernandez ME,Giles DA,Stankiewicz TE,Sheridan R,Karns R,Cappelletti M,Lampe K,Mukherjee R,Sina C,Sallese A,Bridges JP,Hogan SP,Aronow BJ,Hoebe K,Divanovic S
45-7177 was used in Flow cytometry/Cell sorting to demonstrate that β-oxidation links metabolism and immune responsiveness.
Thu Mar 22 00:00:00 EDT 2018
Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring.
Nature
Kim S,Kim H,Yim YS,Ha S,Atarashi K,Tan TG,Longman RS,Honda K,Littman DR,Choi GB,Huh JR
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Thu Sep 28 00:00:00 EDT 2017
miR-146a modulates autoreactive Th17 cell differentiation and regulates organ-specific autoimmunity.
The Journal of clinical investigation
Li B,Wang X,Choi IY,Wang YC,Liu S,Pham AT,Moon H,Smith DJ,Rao DS,Boldin MP,Yang L
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Mon Oct 02 00:00:00 EDT 2017
Microbial, metabolomic, and immunologic dynamics in a relapsing genetic mouse model of colitis induced by T-synthase deficiency.
Gut microbes
Jacobs JP,Lin L,Goudarzi M,Ruegger P,McGovern DP,Fornace AJ,Borneman J,Xia L,Braun J
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Mon Jan 02 00:00:00 EST 2017
Critical role of caspase-8-mediated IL-1 signaling in promoting Th2 responses during asthma pathogenesis.
Mucosal immunology
Qi X,Gurung P,Malireddi RK,Karmaus PW,Sharma D,Vogel P,Chi H,Green DR,Kanneganti TD
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
Subunit vaccine H56/CAF01 induces a population of circulating CD4 T cells that traffic into the Mycobacterium tuberculosis-infected lung.
Mucosal immunology
Woodworth JS,Cohen SB,Moguche AO,Plumlee CR,Agger EM,Urdahl KB,Andersen P
45-7177 was used in Flow cytometry/Cell sorting to elucidate how H56/CAF01 induces a population of circulating CD4 T cells that traffic into the Mycobacterium tuberculosis-infected lung.
Wed Mar 01 00:00:00 EST 2017
Vaccine-induced Th17 cells are established as resident memory cells in the lung and promote local IgA responses.
Mucosal immunology
Christensen D,Mortensen R,Rosenkrands I,Dietrich J,Andersen P
45-7177 was used in Flow cytometry/Cell sorting to demonstrate that subcutaneous priming with a recombinant antigen in a T helper (Th)17-inducing adjuvant followed by airway boosting promotes high and sustained levels of IgA in the lungs.
Sun Jan 01 00:00:00 EST 2017
Chemokine Receptor Ccr7 Restricts Fatal West Nile Virus Encephalitis.
Journal of virology
Bardina SV,Brown JA,Michlmayr D,Hoffman KW,Sum J,Pletnev AG,Lira SA,Lim JK
45-7177 was used in Flow cytometry/Cell sorting to point to Ccr7 as a critical host defense restriction factor limiting neuroinflammation during acute viral infection.
Mon May 15 00:00:00 EDT 2017
Rediscovering peritoneal macrophages in a murine endometriosis model.
Human reproduction (Oxford, England)
Yuan M,Li D,An M,Li Q,Zhang L,Wang G
45-7177 was used in Flow cytometry/Cell sorting to study the role of large and small peritoneal macrophages in endometriosis.
Sun Jan 01 00:00:00 EST 2017
PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune Encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950)
Webb LM,Amici SA,Jablonski KA,Savardekar H,Panfil AR,Li L,Zhou W,Peine K,Karkhanis V,Bachelder EM,Ainslie KM,Green PL,Li C,Baiocchi RA,Guerau-de-Arellano M
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Wed Feb 15 00:00:00 EST 2017
Intragastric administration of Lactobacillus casei BL23 induces regulatory FoxP3+RORγt+ T cells subset in mice.
Beneficial microbes
Cortes-Perez NG,Lozano-Ojalvo D,Maiga MA,Hazebrouck S,Adel-Patient K
45-7177 was used in Flow cytometry/Cell sorting to investigate the mechanisms behind the immunomodulatory properties of the probiotic bacterial strain, Lactobacillus casei BL23.
Tue May 30 00:00:00 EDT 2017
Placenta‑derived mesenchymal stem cells improve airway hyperresponsiveness and inflammation in asthmatic rats by modulating the Th17/Treg balance.
Molecular medicine reports
Li Y,Li H,Cao Y,Wu F,Ma W,Wang Y,Sun S
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Fri Dec 01 00:00:00 EST 2017
Upregulation of SOCS3 in lung CD4+ T cells in a mouse model of chronic PA lung infection and suppression of Th17‑mediated neutrophil recruitment in exogenous SOCS3 transfer in vitro.
Molecular medicine reports
Ding FM,Liao RM,Chen YQ,Xie GG,Zhang PY,Shao P,Zhang M
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Sat Jul 01 00:00:00 EDT 2017
Batf3-dependent CD8α+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages.
EBioMedicine
Li Y,Liu X,Duan W,Tian H,Zhu G,He H,Yao S,Yi S,Song W,Tang H
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation.
Scientific reports
Zhang H,Qi Y,Yuan Y,Cai L,Xu H,Zhang L,Su B,Nie H
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Mon Feb 06 00:00:00 EST 2017
Essential role for CCR6 in certain inflammatory diseases demonstrated using specific antagonist and knockin mice.
JCI insight
Robert R,Ang C,Sun G,Juglair L,Lim EX,Mason LJ,Payne NL,Bernard CC,Mackay CR
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Thu Aug 03 00:00:00 EDT 2017
Traditional Herbal Medicine-Derived Sulforaphene LFS-01 Reverses Colitis in Mice by Selectively Altering the Gut Microbiota and Promoting Intestinal Gamma-Delta T Cells.
Frontiers in pharmacology
Li M,Gao J,Tang Y,Liu M,Wu S,Qu K,Long X,Li H,Liu M,Liu Y,Yuan J,Mao L,Liu Y,Zheng X,Wang E,Wang J,Yang Y
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Wed Sep 30 00:00:00 EDT 2020
Single-cell profiling reveals GPCR heterogeneity and functional patterning during neuroinflammation.
JCI insight
Tischner D,Grimm M,Kaur H,Staudenraus D,Carvalho J,Looso M,Günther S,Wanke F,Moos S,Siller N,Breuer J,Schwab N,Zipp F,Waisman A,Kurschus FC,Offermanns S,Wettschureck N
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Thu Aug 03 00:00:00 EDT 2017
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
A Burkholderia pseudomallei Outer Membrane Vesicle Vaccine Provides Cross Protection against Inhalational Glanders in Mice and Non-Human Primates.
Vaccines
Baker SM,Davitt CJH,Motyka N,Kikendall NL,Russell-Lodrigue K,Roy CJ,Morici LA
45-7177 was used in Flow cytometry/Cell sorting to demonstrate the role of Burkholderia pseudomallei outer membrane vesicle vaccines in cross protection against inhalationalglanders.
Sat Dec 09 00:00:00 EST 2017
An attenuated Mycobacterium tuberculosis clinical strain with a defect in ESX-1 secretion induces minimal host immune responses and pathology.
Scientific reports
Clemmensen HS,Knudsen NPH,Rasmussen EM,Winkler J,Rosenkrands I,Ahmad A,Lillebaek T,Sherman DR,Andersen PL,Aagaard C
45-7177 was used in Flow cytometry/Cell sorting to investigate the Mycobacterium tuberculosis (M.tb) DK9897 strain, showing that it is attenuated and has a defect in ESX-1 secretion, leading to minimal host immune response and pathology.
Mon Apr 24 00:00:00 EDT 2017
Local Th17/IgA immunity correlate with protection against intranasal infection with Streptococcus pyogenes.
PloS one
Mortensen R,Christensen D,Hansen LB,Christensen JP,Andersen P,Dietrich J
45-7177 was used in Flow cytometry/Cell sorting to investigate how protective immunity is related to the route of vaccine administration.
Tue May 09 00:00:00 EDT 2017
Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.
Cell
Chudnovskiy A,Mortha A,Kana V,Kennard A,Ramirez JD,Rahman A,Remark R,Mogno I,Ng R,Gnjatic S,Amir ED,Solovyov A,Greenbaum B,Clemente J,Faith J,Belkaid Y,Grigg ME,Merad M
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Thu Oct 06 00:00:00 EDT 2016
Oligodendrocyte death results in immune-mediated CNS demyelination.
Nature neuroscience
Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
Nuclear receptor expression atlas in BMDCs: Nr4a2 restricts immunogenicity of BMDCs and impedes EAE.
European journal of immunology
Saini A,Mahajan S,Gupta P
45-7177 was used in Flow cytometry/Cell sorting to suggest a previously unidentified role for Nr4a2 as a regulator of DC tolerogenicity and demonstrate its potential as therapeutic target in DC-associated pathophysiologies.
Mon Aug 01 00:00:00 EDT 2016
p(⁷⁰S⁶K¹) in the TORC1 pathway is essential for the differentiation of Th17 Cells, but not Th1, Th2, or Treg cells in mice.
European journal of immunology
Sasaki CY,Chen G,Munk R,Eitan E,Martindale J,Longo DL,Ghosh P
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
Rapamycin ameliorates CCl4-induced liver fibrosis in mice through reciprocal regulation of the Th17/Treg cell balance.
Molecular medicine reports
Gu L,Deng WS,Sun XF,Zhou H,Xu Q
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Age-dependent divergent effects of OX40L treatment on the development of diabetes in NOD mice.
Autoimmunity
Haddad CS,Bhattacharya P,Alharshawi K,Marinelarena A,Kumar P,El-Sayed O,Elshabrawy HA,Epstein AL,Prabhakar BS
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Tropomyosin Receptor Kinase C Targeted Delivery of a Peptidomimetic Ligand-Photosensitizer Conjugate Induces Antitumor Immune Responses Following Photodynamic Therapy.
Scientific reports
Kue CS,Kamkaew A,Voon SH,Kiew LV,Chung LY,Burgess K,Lee HB
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Thu Nov 17 00:00:00 EST 2016
Regulation of Inflammation by IL-17A and IL-17F Modulates Non-Alcoholic Fatty Liver Disease Pathogenesis.
PloS one
Giles DA,Moreno-Fernandez ME,Stankiewicz TE,Cappelletti M,Huppert SS,Iwakura Y,Dong C,Shanmukhappa SK,Divanovic S
45-7177 was used in Flow cytometry/Cell sorting to indicate that the IL-17 axis also plays a role in a MCDD-induced model of NAFLD pathogenesis.
Tue Jul 19 00:00:00 EDT 2016
Tamm-Horsfall Protein Regulates Granulopoiesis and Systemic Neutrophil Homeostasis.
Journal of the American Society of Nephrology : JASN
Micanovic R,Chitteti BR,Dagher PC,Srour EF,Khan S,Hato T,Lyle A,Tong Y,Wu XR,El-Achkar TM
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice.
Proceedings of the National Academy of Sciences of the United States of America
Wu L,Li N,Zhang M,Xue SL,Cassady K,Lin Q,Riggs AD,Zeng D
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Tue Dec 29 00:00:00 EST 2015
B-cell very late antigen-4 deficiency reduces leukocyte recruitment and susceptibility to central nervous system autoimmunity.
Annals of neurology
Lehmann-Horn K,Sagan SA,Bernard CC,Sobel RA,Zamvil SS
45-7177 was used in Flow cytometry/Cell sorting to report that the selective inhibition of VLA-4 expression on B cells impedes CNS accumulation of B cells, and recruitment of Th17 cells and macrophages.
Fri May 01 00:00:00 EDT 2015
Unexpected Role for Adaptive αβTh17 Cells in Acute Respiratory Distress Syndrome.
Journal of immunology (Baltimore, Md. : 1950)
Li JT,Melton AC,Su G,Hamm DE,LaFemina M,Howard J,Fang X,Bhat S,Huynh KM,O'Kane CM,Ingram RJ,Muir RR,McAuley DF,Matthay MA,Sheppard D
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2015
Interleukin-25 Mediates Transcriptional Control of PD-L1 via STAT3 in Multipotent Human Mesenchymal Stromal Cells (hMSCs) to Suppress Th17 Responses.
Stem cell reports
Wang WB,Yen ML,Liu KJ,Hsu PJ,Lin MH,Chen PM,Sudhir PR,Chen CH,Chen CH,Sytwu HK,Yen BL
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Tue Sep 08 00:00:00 EDT 2015
A Multiple Antigenic Peptide Mimicking Peptidoglycan Induced T Cell Responses to Protect Mice from Systemic Infection with Staphylococcus aureus.
PloS one
Wang XY,Huang ZX,Chen YG,Lu X,Zhu P,Wen K,Fu N,Liu BY
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Tue May 24 00:00:00 EDT 2016
Upregulation of Programmed Death-1 and Its Ligand in Cardiac Injury Models: Interaction with GADD153.
PloS one
Baban B,Liu JY,Qin X,Weintraub NL,Mozaffari MS
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Tue Apr 12 00:00:00 EDT 2016
Protective CD4 T cells targeting cryptic epitopes of Mycobacterium tuberculosis resist infection-driven terminal differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Woodworth JS,Aagaard CS,Hansen PR,Cassidy JP,Agger EM,Andersen P
45-7177 was used in Flow cytometry/Cell sorting to compare the functionality of CD4 T cell responses mounted against dominant and cryptic epitopes of the Mycobacterium tuberculosis 6-kDa early secreted antigen before and postinfection.
Tue Apr 01 00:00:00 EDT 2014
A chitin-like component on sclerotic cells of Fonsecaea pedrosoi inhibits Dectin-1-mediated murine Th17 development by masking β-glucans.
PloS one
Dong B,Li D,Li R,Chen SC,Liu W,Liu W,Chen L,Chen Y,Zhang X,Tong Z,Xia Y,Xia P,Wang Y,Duan Y
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2015
Worm proteins of Schistosoma mansoni reduce the severity of experimental chronic colitis in mice by suppressing colonic proinflammatory immune responses.
PloS one
Heylen M,Ruyssers NE,De Man JG,Timmermans JP,Pelckmans PA,Moreels TG,De Winter BY
45-7177 was used in Flow cytometry/Cell sorting to investigate the therapeutic potential and immunological mechanisms of Schistosoma mansoni soluble worm protein in an adoptive T cell transfer mouse model of chronic colitis.
Tue Jun 23 00:00:00 EDT 2015
A new recombinant BCG vaccine induces specific Th17 and Th1 effector cells with higher protective efficacy against tuberculosis.
PloS one
da Costa AC,Costa-Júnior Ade O,de Oliveira FM,Nogueira SV,Rosa JD,Resende DP,Kipnis A,Junqueira-Kipnis AP
45-7177 was used in Flow cytometry/Cell sorting to evaluate the immunogenicity and protection of a new BCG vaccine against TB, showing that it induces specific Th17 and Th1 effector cells with higher protective efficacy.
Fri Dec 18 00:00:00 EST 2015
R-phycoerythrin-conjugated antibodies are inappropriate for intracellular staining of murine plasma cells.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Kim MS,Kim TS
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Wed May 01 00:00:00 EDT 2013
Interleukin-22 as a molecular adjuvant facilitates IL-17-producing CD8+ T cell responses against a HBV DNA vaccine in mice.
Human vaccines & immunotherapeutics
Wu B,Zou Q,Hu Y,Wang B
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2013
Activation of CD4+ T lymphocytes improves wound healing and survival after experimental myocardial infarction in mice.
Circulation
Hofmann U,Beyersdorf N,Weirather J,Podolskaya A,Bauersachs J,Ertl G,Kerkau T,Frantz S
45-7177 was used in Flow cytometry/Cell sorting to investigate the role of CD4+ T lymphocytes in wound healing after experimental myocardial infarction in mice.
Tue Apr 03 00:00:00 EDT 2012
Efficient capture of infected neutrophils by dendritic cells in the skin inhibits the early anti-leishmania response.
PLoS pathogens
Ribeiro-Gomes FL,Peters NC,Debrabant A,Sacks DL
45-7177 was used in Flow cytometry/Cell sorting to study how exploitation of immunosuppressive effects by L.major following rapid uptake by skin neutrophils allows inhibition of acquired resistance.
Wed Feb 01 00:00:00 EST 2012
In vitro culture medium influences the vaccine efficacy of Mycobacterium bovis BCG.
Vaccine
Venkataswamy MM,Goldberg MF,Baena A,Chan J,Jacobs WR,Porcelli SA
45-7177 was used in Flow cytometry/Cell sorting to review the manufacturing process of the mycobacterium bovis BCG vaccine.
Wed Feb 01 00:00:00 EST 2012
Vaccine-induced th17 cells are maintained long-term postvaccination as a distinct and phenotypically stable memory subset.
Infection and immunity
Lindenstrøm T,Woodworth J,Dietrich J,Aagaard C,Andersen P,Agger EM
45-7177 was used in Flow cytometry/Cell sorting to demonstrate that subunit vaccination in mice with CAF01 leads to establishment of bona fide Th17 memory cells.
Mon Oct 01 00:00:00 EDT 2012
Soluble MOG35-55/I-A(b) dimers ameliorate experimental autoimmune encephalomyelitis by reducing encephalitogenic T cells.
PloS one
Gong Y,Wang Z,Liang Z,Duan H,Ouyang L,Yu Q,Xu Z,Shen G,Weng X,Wu X
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Fri Jul 19 00:00:00 EDT 2013
Anti-IL-23 antibody blockade of IL-23/IL-17 pathway attenuates airway obliteration in rat orthotopic tracheal transplantation.
International immunopharmacology
Cao H,Lan Q,Shi Q,Zhou X,Liu G,Liu J,Tang G,Qiu C,Qiu C,Xu J,Fan H,Liu Z
Sun May 01 00:00:00 EDT 2011
The magnitude of CD4(+) T-cell activation rather than TCR diversity determines the outcome of Leishmania infection in mice.
Parasite immunology
Xin L,Wanderley JL,Wang Y,Vargas-Inchaustegui DA,Soong L
45-7177 was used in Flow cytometry/Cell sorting to investigate TCR usage in Leishmania-specific, IFN-γ-producing CD4(+) T cells, showing that the magnitude of activation rather than TCR diversity determines the outcome of infection.
Tue Mar 01 00:00:00 EST 2011
T cells from Programmed Death-1 deficient mice respond poorly to Mycobacterium tuberculosis infection.
PloS one
Tousif S,Singh Y,Prasad DV,Sharma P,Van Kaer L,Das G
Thu May 12 00:00:00 EDT 2011
Role of epithelial integrin-linked kinase in promoting intestinal inflammation: effects on CCL2, fibronectin and the T cell repertoire.
BMC immunology
Assi K,Patterson S,Dedhar S,Owen D,Levings M,Salh B
Mon Aug 01 00:00:00 EDT 2011
IDO activates regulatory T cells and blocks their conversion into Th17-like T cells.
Journal of immunology (Baltimore, Md. : 1950)
Baban B,Chandler PR,Sharma MD,Pihkala J,Koni PA,Munn DH,Mellor AL
Published figure using IL-17A monoclonal antibody (Product # 45-7177-82) in Flow Cytometry
Sat Aug 15 00:00:00 EDT 2009
Early life exposure to lipopolysaccharide suppresses experimental autoimmune encephalomyelitis by promoting tolerogenic dendritic cells and regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
Ellestad KK,Tsutsui S,Noorbakhsh F,Warren KG,Yong VW,Pittman QJ,Power C
Wed Jul 01 00:00:00 EDT 2009
Distinct roles for MyD88 and Toll-like receptor 2 during Leishmania braziliensis infection in mice.
Infection and immunity
Vargas-Inchaustegui DA,Tai W,Xin L,Hogg AE,Corry DB,Soong L
45-7177 was used in Flow cytometry/Cell sorting to investigate whether TLRs are involved in L. braziliensis-mediated dendritic cell activation, showing distinct roles for MyD88 and TLR2 in infection.
Wed Jul 01 00:00:00 EDT 2009