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Alomone Labs, LTD
5HT7 Receptor/HTR7 (extracellular) Polyclonal Antibody, FITC
Application
FIGURE: 1 / 2
5HT7 Receptor/HTR7 (extracellular) Antibody (ASR-037-F-50UL) in Flow
Cell surface detection of 5HT7 Receptor by direct flow cytometry in live intact human MEG-01 megakaryoblastic leukemia cells: - (black line) cells. (red) Cells + Rabbit IgG Isotype Control-FITC. (green) Cells + Anti-5HT7 Receptor/HTR7 (extracellular)-FITC Antibody (#ASR-037-F), (5 µg).
Product Details
ASR-037-F-50UL
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide CGEQINYGRVEK, corresponding to amino acid residues 73-84 of rat 5-HT7, Extracellular, N-terminus
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Lyophilized
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 15 µL or 50 µL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
5-HT7 Receptor is a Serotonin Receptor with several functions, including regulation of the circadian rhythm and mediation of smooth-muscle relaxation in the vasculature and GI tract. This receptor has been implicated in depression, autism, and other neuropsychiatric disorders. Three protein isoforms have been documented: isoform a: 445aa; isoform b: 432aa; isoform d: 479aa. 5-HT7 Receptor has been reported in aorta, brain, heart, placenta, small intestine, spleen, artery, and vessel. An EST has been isolated from a testis library.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5-HT-7; 5-HT-X; 5-HT7; 5-HT7 receptor; 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled); 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled; 5-hydroxytryptamine receptor 7; 5HT7 Receptor; GPRFO; high affinity serotonin receptor (5HT7); HT7; OTTHUMP00000020077; OTTHUMP00000020078; OTTHUMP00000020079; Serotonin receptor 7
Gene Aliases: 5-HT7; 5Ht7; HTR7
UniProt ID: (Human) P34969, (Mouse) P32304, (Rat) P32305
Entrez Gene ID: (Human) 3363, (Mouse) 15566, (Rat) 65032
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