Invitrogen

CD14 Monoclonal Antibody (61D3), PE-eFluor™ 610, eBioscience™

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Antibody Testing Data (1)
Published Figures (44)

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CD14 Antibody (61-0149-42) in Flow

Staining of normal human peripheral blood cells with Anti-Human CD11b APC (Product # 17-0118-42) and Mouse IgG1 K Isotype Control PE-eFluor® 610 (Product # 61-4714-82) (left) or Anti-Human CD14 PE-eFluor® 610 (right). Cells in the monocyte gate were used for analysis.

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Product Details

61-0149-42

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

5 µL (0.25 µg)/test

View 47 publications 47 publications

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Mouse / IgG1, kappa

Recommended Isotype Control

Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), PE-eFluor™ 610, eBioscience™

Class

Monoclonal

Type

Antibody

Clone

61D3

Conjugate

PE-eFluor™ 610 PE-eFluor™ 610 PE-eFluor™ 610

Excitation/Emission Max

565/606 nm View spectra

Form

Liquid

Concentration

5 µL/Test

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2, with 0.2% BSA

Contains

0.09% sodium azide

Storage conditions

4° C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2574534

Product Specific Information

Description: The 61D3 monoclonal antibody reacts with human CD14, a 53-55 kDa GPI-linked glycoprotein. CD14 is expressed on monocytes, interfollicular macrophages and some dendritic cells. Complexes of LPS and LBP (LPS-Binding Protein) bind with high affinity to monocytes through the surface CD14.

Applications Reported: This 61D3 antibody has been reported for use in flow cytometric analysis.

Applications Tested: This 61D3 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.25 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

PE-eFluor® 610 can be excited with laser lines from 488-561 nm and emits at 607 nm. We recommend using a 610/20 band pass filter (equivalent to PE-Texas Red®). Please make sure that your instrument is capable of detecting this fluorochrome.

Light sensitivity: This tandem dye is sensitive to photo-induced oxidation. Please protect this vial and stained samples from light.

Fixation: Samples can be stored in IC Fixation Buffer (Product # 00-8222) (100 µL of cell sample + 100 µL of IC Fixation Buffer) or 1-step Fix/Lyse Solution (Product # 00-5333) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically.

Excitation: 488-561 nm; Emission: 607 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.

Filtration: 0.2 µm post-manufacturing filtered.

Target Information

CD14 is a 55 kDa GPI-anchored glycoprotein that is constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils. CD14 also serves as a multifunctional lipopolysaccharide receptor, and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 can discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. Further, CD14 has been shown to bind apoptotic cells, and can affect allergic, inflammatory and infectious processes. Alternative splicing results in multiple transcript variants encoding the same CD14 isoform. Diseases associated with CD14 dysfunction include mycobacterium chelonae infection and Croup.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Product References

LAL deficiency induced myeloid-derived suppressor cells as targets and biomarkers for lung cancer.

Journal for immunotherapy of cancer

Zhao T,Liu S,Hanna NH,Jalal S,Ding X,Wan J,Yan C,Du H

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2023

The XIST lncRNA is a sex-specific reservoir of TLR7 ligands in SLE.

JCI insight

Crawford JD,Wang H,Trejo-Zambrano D,Cimbro R,Talbot CC,Thomas MA,Curran AM,Girgis AA,Schroeder JT,Fava A,Goldman DW,Petri M,Rosen A,Antiochos B,Darrah E

61-0149-42 was used in Flow cytometry/Cell sorting to suggest a novel role for XIST RNA as a female-specific danger signal underlying the sex bias in SLE.

Thu Sep 21 00:00:00 EDT 2023

Spontaneous Osteoclastogenesis, a risk factor for bone metastasis in advanced luminal A-type breast cancer patients.

Frontiers in oncology

Fernández Vallone V,Borzone FR,Martinez LM,Giorello MB,Choi H,Dimase F,Feldman L,Bordenave RH,Chudzinski-Tavassi AM,Batagelj E,Chasseing NA

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Fri Mar 10 00:00:00 EST 2023

SARS-CoV-2 Delta (B.1.617.2) variant replicates and induces syncytia formation in human induced pluripotent stem cell-derived macrophages.

PeerJ

Thaweerattanasinp T,Wanitchang A,Saenboonrueng J,Srisutthisamphan K,Wanasen N,Sungsuwan S,Jongkaewwattana A,Chailangkarn T

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Thu Mar 09 00:00:00 EST 2023

Heliangin acts as a covalent ligand of RPS2 that disrupts pre-rRNA metabolic processes in NPM1-mutated acute myeloid leukemia.

Acta pharmaceutica Sinica. B

Feng Y,Han Y,Hu A,Qu Y,Hu Y,Wu H,Wang X,He L

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Wed Feb 01 00:00:00 EST 2023

A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.

Journal of medicinal chemistry

Marín-Rubio JL,Peltier-Heap RE,Dueñas ME,Heunis T,Dannoura A,Inns J,Scott J,Simpson AJ,Blair HJ,Heidenreich O,Allan JM,Watt JE,Martin MP,Saxty B,Trost M

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Thu Sep 22 00:00:00 EDT 2022

Decoding the pathogenesis of Diamond-Blackfan anemia using single-cell RNA-seq.

Cell discovery

Wang B,Wang C,Wan Y,Gao J,Ma Y,Zhang Y,Tong J,Zhang Y,Liu J,Chang L,Xu C,Shen B,Chen Y,Jiang E,Kurita R,Nakamura Y,Lim KC,Engel JD,Zhou J,Cheng T,Zhu X,Zhu P,Shi L

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Tue May 10 00:00:00 EDT 2022

Humanized mice reveal a macrophage-enriched gene signature defining human lung tissue protection during SARS-CoV-2 infection.

Cell reports

Kenney DJ,O'Connell AK,Turcinovic J,Montanaro P,Hekman RM,Tamura T,Berneshawi AR,Cafiero TR,Al Abdullatif S,Blum B,Goldstein SI,Heller BL,Gertje HP,Bullitt E,Trachtenberg AJ,Chavez E,Nono ET,Morrison C,Tseng AE,Sheikh A,Kurnick S,Grosz K,Bosmann M,Ericsson M,Huber BR,Saeed M,Balazs AB,Francis KP,Klose A,Paragas N,Campbell JD,Connor JH,Emili A,Crossland NA,Ploss A,Douam F

61-0149-42 was used in Flow cytometry/Cell sorting to highlight the HNFL model as a transformative platform to investigate, in controlled experimental settings, human myeloid immune mechanisms governing lung tissue protection during SARS-CoV-2 infection.

Tue Apr 19 00:00:00 EDT 2022

PD-1-Expressing SARS-CoV-2-Specific CD8⁺ T Cells Are Not Exhausted, but Functional in Patients with COVID-19.

Immunity

Rha MS,Jeong HW,Ko JH,Choi SJ,Seo IH,Lee JS,Sa M,Kim AR,Joo EJ,Ahn JY,Kim JH,Song KH,Kim ES,Oh DH,Ahn MY,Choi HK,Jeon JH,Choi JP,Kim HB,Kim YK,Park SH,Choi WS,Choi JY,Peck KR,Shin EC

61-0149-42 was used in Flow Cytometry to detect SARS-CoV-2-specific CD8+ T cells and examine their phenotypes and functions in acute and convalescent COVID-19.

Tue Jan 12 00:00:00 EST 2021

SARS-CoV-2 infection paralyzes cytotoxic and metabolic functions of the immune cells.

Heliyon

Singh Y,Trautwein C,Fendel R,Krickeberg N,Berezhnoy G,Bissinger R,Ossowski S,Salker MS,Casadei N,Riess O

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Tue Jun 01 00:00:00 EDT 2021

uPAR⁺ extracellular vesicles: a robust biomarker of resistance to checkpoint inhibitor immunotherapy in metastatic melanoma patients.

Journal for immunotherapy of cancer

Porcelli L,Guida M,De Summa S,Di Fonte R,De Risi I,Garofoli M,Caputo M,Negri A,Strippoli S,Serratì S,Azzariti A

Sat May 01 00:00:00 EDT 2021

The long non-coding RNA Cancer Susceptibility 15 (CASC15) is induced by isocitrate dehydrogenase (IDH) mutations and maintains an immature phenotype in adult acute myeloid leukemia.

Haematologica

Grasedieck S,Ruess C,Krowiorz K,Lux S,Pochert N,Schwarzer A,Klusmann JH,Jongen-Lavrencic M,Herold T,Bullinger L,Pollack JR,Rouhi A,Kuchenbauer F

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Tue Sep 01 00:00:00 EDT 2020

Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruzi strains unveil a role for fibroblasts in neutrophil recruitment and activation.

PLoS pathogens

Oliveira AER,Pereira MCA,Belew AT,Ferreira LRP,Pereira LMN,Neves EGA,Nunes MDCP,Burleigh BA,Dutra WO,El-Sayed NM,Gazzinelli RT,Teixeira SMR

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Sat Aug 01 00:00:00 EDT 2020

A functional antibody cross-reactive to both human and murine cytotoxic T-lymphocyte-associated protein 4 via binding to an N-glycosylation epitope.

mAbs

Li D,Li J,Chu H,Wang Z

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Fri Feb 12 00:00:00 EST 2021

Differentiation Potential of Early- and Late-Passage Adipose-Derived Mesenchymal Stem Cells Cultured under Hypoxia and Normoxia.

Stem cells international

Zhao AG,Shah K,Freitag J,Cromer B,Sumer H

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Tue Oct 06 00:00:00 EDT 2020

MiR-103 protects from recurrent spontaneous abortion via inhibiting STAT1 mediated M1 macrophage polarization.

International journal of biological sciences

Zhu X,Liu H,Zhang Z,Wei R,Zhou X,Wang Z,Zhao L,Guo Q,Zhang Y,Chu C,Wang L,Li X

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Fri Nov 12 00:00:00 EST 2021

Patient iPSC-Derived Macrophages to Study Inborn Errors of the IFN-γ Responsive Pathway.

Cells

Haake K,Neehus AL,Buchegger T,Kühnel MP,Blank P,Philipp F,Oleaga-Quintas C,Schulz A,Grimley M,Goethe R,Jonigk D,Kalinke U,Boisson-Dupuis S,Casanova JL,Bustamante J,Lachmann N

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Wed Feb 19 00:00:00 EST 2020

Chemerin enhances the adhesion and migration of human endothelial progenitor cells and increases lipid accumulation in mice with atherosclerosis.

Lipids in health and disease

Jia J,Yu F,Xiong Y,Wei W,Ma H,Nisi F,Song X,Yang L,Wang D,Yuan G,Zhou H

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Sun Sep 20 00:00:00 EDT 2020

NLRP3 Inflammasome Activation in Hemodialysis and Hypertensive Patients with Intact Kidney Function.

Toxins

Ulrich C,Wildgrube S,Fiedler R,Seibert E,Kneser L,Fick S,Schäfer C,Markau S,Trojanowicz B,Girndt M

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Mon Oct 26 00:00:00 EDT 2020

LILRB3 (ILT5) is a myeloid cell checkpoint that elicits profound immunomodulation.

JCI insight

Yeboah M,Papagregoriou C,Jones DC,Chan HTC,Hu G,McPartlan JS,Schiött T,Mattson U,Mockridge CI,Tornberg UC,Hambe B,Ljungars A,Mattsson M,Tews I,Glennie MJ,Thirdborough SM,Trowsdale J,Frendeus B,Chen J,Cragg MS,Roghanian A

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Tue Sep 01 00:00:00 EDT 2020

NLRP3 inflammasome expression in peripheral blood monocytes of coronary heart disease patients and its modulation by rosuvastatin.

Molecular medicine reports

Zhu J,Wu S,Hu S,Li H,Li M,Geng X,Wang H

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Thu Aug 01 00:00:00 EDT 2019

Characterizing the Role of Monocytes in T Cell Cancer Immunotherapy Using a 3D Microfluidic Model.

Frontiers in immunology

Lee SWL,Adriani G,Ceccarello E,Pavesi A,Tan AT,Bertoletti A,Kamm RD,Wong SC

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Mon Jun 24 00:00:00 EDT 2019

AURKA Suppresses Leukemic THP-1 Cell Differentiation through Inhibition of the KDM6B Pathway.

Molecules and cells

Park JW,Cho H,Oh H,Kim JY,Seo SB

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Thu May 31 00:00:00 EDT 2018

Butyrate upregulates the TLR4 expression and the phosphorylation of MAPKs and NK-κB in colon cancer cell in vitro.

Oncology letters

Xiao T,Wu S,Yan C,Zhao C,Jin H,Yan N,Xu J,Wu Y,Li C,Shao Q,Xia S

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Mon Oct 01 00:00:00 EDT 2018

Impaired efferocytosis by monocytes in multiple myeloma.

Oncology letters

Liang YY,Schwarzinger I,Simonitsch-Klupp I,Agis H,Oehler R

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Sun Jul 01 00:00:00 EDT 2018

Human umbilical cord-derived mesenchymal stem cells ameliorate the enteropathy of food allergies in mice.

Experimental and therapeutic medicine

Yan N,Xu J,Zhao C,Wu Y,Gao F,Li C,Zhou W,Xiao T,Zhou X,Shao Q,Xia S

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Sat Dec 01 00:00:00 EST 2018

Comprehensive characterization of chorionic villi-derived mesenchymal stromal cells from human placenta.

Stem cell research & therapy

Ventura Ferreira MS,Bienert M,Müller K,Rath B,Goecke T,Opländer C,Braunschweig T,Mela P,Brümmendorf TH,Beier F,Neuss S

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Mon Feb 05 00:00:00 EST 2018

Cellular metabolism constrains innate immune responses in early human ontogeny.

Nature communications

Kan B,Michalski C,Fu H,Au HHT,Lee K,Marchant EA,Cheng MF,Anderson-Baucum E,Aharoni-Simon M,Tilley P,Mirmira RG,Ross CJ,Luciani DS,Jan E,Lavoie PM

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Fri Nov 16 00:00:00 EST 2018

The pro-inflammatory phenotype of the human non-classical monocyte subset is attributed to senescence.

Cell death & disease

Ong SM,Hadadi E,Dang TM,Yeap WH,Tan CT,Ng TP,Larbi A,Wong SC

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Thu Feb 15 00:00:00 EST 2018

EDAG promotes the expansion and survival of human CD34+ cells.

PloS one

Zhao K,Zheng WW,Dong XM,Yin RH,Gao R,Li X,Liu JF,Zhan YQ,Yu M,Chen H,Ge CH,Ning HM,Yang XM,Li CY

61-0149 was used in Flow cytometry/Cell sorting to provide novel insight into EDAG in regulation of expansion and survival of human hematopoietic stem/progenitor cells.

Tue Feb 06 00:00:00 EST 2018

A therapeutic T cell receptor mimic antibody targets tumor-associated PRAME peptide/HLA-I antigens.

The Journal of clinical investigation

Chang AY,Dao T,Gejman RS,Jarvis CA,Scott A,Dubrovsky L,Mathias MD,Korontsvit T,Zakhaleva V,Curcio M,Hendrickson RC,Liu C,Scheinberg DA

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Fri Jun 30 00:00:00 EDT 2017

Human umbilical cord mesenchymal stem cells improve the reserve function of perimenopausal ovary via a paracrine mechanism.

Stem cell research & therapy

Li J,Mao Q,He J,She H,Zhang Z,Yin C

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Thu Mar 09 00:00:00 EST 2017

Single-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome.

Nature communications

Douam F,Hrebikova G,Albrecht YE,Sellau J,Sharon Y,Ding Q,Ploss A

61-0149 was used in Flow cytometry/Cell sorting to demonstrate the tracking of and sense viral RNA at single-cell resolution within complex subsets of the human and murine immune system in different mouse models.

Tue Mar 14 00:00:00 EDT 2017

Pulmonary sarcoidosis is associated with high-level inducible co-stimulator (ICOS) expression on lung regulatory T cells--possible implications for the ICOS/ICOS-ligand axis in disease course and resolution.

Clinical and experimental immunology

Sakthivel P,Grunewald J,Eklund A,Bruder D,Wahlström J

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Mon Feb 01 00:00:00 EST 2016

Thrombomodulin regulates monocye differentiation via PKCδ and ERK1/2 pathway in vitro and in atherosclerotic artery.

Scientific reports

Tsai CS,Lin YW,Huang CY,Shih CM,Tsai YT,Tsao NW,Lin CS,Shih CC,Jeng H,Lin FY

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Fri Dec 02 00:00:00 EST 2016

STK4 regulates TLR pathways and protects against chronic inflammation-related hepatocellular carcinoma.

The Journal of clinical investigation

Li W,Xiao J,Zhou X,Xu M,Hu C,Xu X,Lu Y,Liu C,Xue S,Nie L,Zhang H,Li Z,Zhang Y,Ji F,Hui L,Tao W,Wei B,Wang H

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Mon Nov 02 00:00:00 EST 2015

Liposomal Glutathione Supplementation Restores TH1 Cytokine Response to Mycobacterium tuberculosis Infection in HIV-Infected Individuals.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research

Ly J,Lagman M,Saing T,Singh MK,Tudela EV,Morris D,Anderson J,Daliva J,Ochoa C,Patel N,Pearce D,Venketaraman V

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Sun Nov 01 00:00:00 EDT 2015

Investigating the causes for decreased levels of glutathione in individuals with type II diabetes.

PloS one

Lagman M,Ly J,Saing T,Kaur Singh M,Vera Tudela E,Morris D,Chi PT,Ochoa C,Sathananthan A,Venketaraman V

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Wed Dec 30 00:00:00 EST 2015

A novel antibody-drug conjugate targeting SAIL for the treatment of hematologic malignancies.

Blood cancer journal

Kim SY,Theunissen JW,Balibalos J,Liao-Chan S,Babcock MC,Wong T,Cairns B,Gonzalez D,van der Horst EH,Perez M,Levashova Z,Chinn L,D'Alessio JA,Flory M,Bermudez A,Jackson DY,Ha E,Monteon J,Bruhns MF,Chen G,Migone TS

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Fri May 29 00:00:00 EDT 2015

Human mesenchymal stem cells possess different biological characteristics but do not change their therapeutic potential when cultured in serum free medium.

Stem cell research & therapy

Wang Y,Wu H,Yang Z,Chi Y,Meng L,Mao A,Yan S,Hu S,Zhang J,Zhang Y,Yu W,Ma Y,Li T,Cheng Y,Wang Y,Wang S,Liu J,Han J,Li C,Liu L,Xu J,Han ZB,Han ZC

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Thu Dec 04 00:00:00 EST 2014

Biologically active polymers from spontaneous carotenoid oxidation: a new frontier in carotenoid activity.

PloS one

Johnston JB,Nickerson JG,Daroszewski J,Mogg TJ,Burton GW

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Thu Jun 25 00:00:00 EDT 2015

Noncanonical dendritic cell differentiation and survival driven by a bacteremic pathogen.

Journal of leukocyte biology

Miles B,Scisci E,Carrion J,Sabino GJ,Genco CA,Cutler CW

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Thu Aug 01 00:00:00 EDT 2013

Induction of autophagy is essential for monocyte-macrophage differentiation.

Blood

Zhang Y,Morgan MJ,Chen K,Choksi S,Liu ZG

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Thu Mar 22 00:00:00 EDT 2012

Negative regulation of JAK2 by H3K9 methyltransferase G9a in leukemia.

Molecular and cellular biology

Son HJ,Kim JY,Hahn Y,Seo SB

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Sat Sep 01 00:00:00 EDT 2012

Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients.

Critical care (London, England)

Zhang Y,Li J,Lou J,Zhou Y,Bo L,Zhu J,Zhu K,Wan X,Cai Z,Deng X

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Wed Dec 07 00:00:00 EST 2011

Ro60-associated single-stranded RNA links inflammation with fetal cardiac fibrosis via ligation of TLRs: a novel pathway to autoimmune-associated heart block.

Journal of immunology (Baltimore, Md. : 1950)

Clancy RM,Alvarez D,Komissarova E,Barrat FJ,Swartz J,Buyon JP

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Mon Feb 15 00:00:00 EST 2010

B cells and monocytes from patients with active multiple sclerosis exhibit increased surface expression of both HERV-H Env and HERV-W Env, accompanied by increased seroreactivity.

Retrovirology

Brudek T,Christensen T,Aagaard L,Petersen T,Hansen HJ,Møller-Larsen A

Published figure using CD14 monoclonal antibody (Product # 61-0149-42) in Flow Cytometry

Mon Nov 16 00:00:00 EST 2009

Bioinformatics

Protein Aliases: CD 14; CD14; cd14 monocyte; LPSR antibody; Monocyte differentiation antigen CD14; My23 antigen; Myeloid cell-specific leucine-rich glycoprotein; sCD14; soluble CD14

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Gene Aliases: CD14

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UniProt ID: (Human) P08571

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Entrez Gene ID: (Human) 929

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Function(s)

lipopolysaccharide binding opsonin receptor activity protein binding peptidoglycan receptor activity lipoteichoic acid binding transmembrane signal receptor

Process(es)

MyD88-dependent toll-like receptor signaling pathway MyD88-independent toll-like receptor signaling pathway receptor-mediated endocytosis phagocytosis apoptotic process inflammatory response cell surface receptor signaling pathway I-kappaB kinase/NF-kappaB signaling response to heat lipopolysaccharide-mediated signaling pathway response to magnesium ion positive regulation of type I interferon production positive regulation of interferon-gamma production positive regulation of tumor necrosis factor production negative regulation of MyD88-independent toll-like receptor signaling pathway toll-like receptor 4 signaling pathway response to tumor necrosis factor TRIF-dependent toll-like receptor signaling pathway toll-like receptor TLR1:TLR2 signaling pathway toll-like receptor TLR6:TLR2 signaling pathway innate immune response response to ethanol positive regulation of endocytosis positive regulation of cytokine secretion response to electrical stimulus necroptotic process cellular response to lipopolysaccharide cellular response to lipoteichoic acid cellular response to diacyl bacterial lipopeptide cellular response to triacyl bacterial lipopeptide apoptotic signaling pathway

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CD14 Monoclonal Antibody (61D3), PE-eFluor™ 610, eBioscience™

CD14 Antibody (61-0149-42) in Flow

Product Details

61-0149-42

Flow Cytometry (Flow)

Species Reactivity

Published species

Host/Isotype

Recommended Isotype Control

Class

Type

Clone

Conjugate

Excitation/Emission Max

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

How to use the Panel Builder

Bioinformatics

Performance Guarantee

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