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Invitrogen

ABCB5 Polyclonal Antibody

View all (10) ABCB5 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (1)

Application

ABCB5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 1

ABCB5 Antibody (PA5-72966) in IHC (P)

Immunohistochemical analysis of ABCB5 in mouse spleen. Samples were incubated with ABCB5 polyclonal antibody (Product # PA5-72966) followed by using DAB with hematoxylin counterstain.

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Product Details

PA5-72966

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-Dependent

Immunohistochemistry (Paraffin) (IHC (P))

1:200

Immunocytochemistry (ICC/IF)

1:100

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide made to an internal portion of the human ABCB5 protein (between residues 150-200) [UniProt Q2M3G0]

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 30% glycerol

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2718820

Target Information

ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: ABCB5 P-gp; ATP-binding cassette protein; ATP-binding cassette sub-family B member 5; ATP-binding cassette, sub-family B (MDR/TAP), member 5; P-glycoprotein ABCB5

Gene Aliases: 9230106F14Rik; ABCB5; ABCB5alpha; ABCB5beta; EST422562

UniProt ID: (Human) Q2M3G0, (Mouse) B5X0E4

Entrez Gene ID: (Human) 340273, (Mouse) 77706

Function(s)

ATP binding xenobiotic-transporting ATPase activity efflux transmembrane transporter activity ATPase activity, coupled to transmembrane movement of substances nucleotide binding ATPase activity ATP-binding cassette (ABC) transporter

Process(es)

antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent positive regulation of antigen processing and presentation of peptide antigen via MHC class I drug transmembrane transport cell differentiation regulation of membrane potential xenobiotic transport compound eye corneal lens development transmembrane transport transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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