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This gene encodes a cytoskeletal LIM protein that binds to actin filaments via a domain that is homologous to erythrocyte dematin. LIM domains, found in over 60 proteins, play key roles in the regulation of developmental pathways. LIM domains also function as protein-binding interfaces, mediating specific protein-protein interactions. The protein encoded by this gene could mediate such interactions between actin filaments and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: abLIM-1; Actin-binding double zinc finger protein; actin-binding double-zinc-finger protein; Actin-binding LIM protein 1; Actin-binding LIM protein family member 1; LIMAB1; Limatin
Gene Aliases: 2210411C18Rik; 2610209L21Rik; 4833406P10Rik; 9330196J19Rik; ABLIM; abLIM-1; ABLIM1; AV079770; AW060987; AW215784; KIAA0059; LIMAB1; LIMATIN; mKIAA0059
UniProt ID: (Human) O14639, (Mouse) Q8K4G5
Entrez Gene ID: (Human) 3983, (Mouse) 226251
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