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Proteintech
ACC1 Monoclonal Antibody (1A11G10), CoraLite® 594
Product Details
CL59467373100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
1A11G10
Conjugate
Excitation/Emission Max
593/614 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Wet ice
Target Information
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ACC-alpha; ACC1; Acetyl-CoA carboxylase 1; Acetyl-Coenzyme A carboxylase alpha; EC 6.3.4.14; EC 6.4.1.2
Gene Aliases: ACAC; ACACA; ACACAD; ACC; ACC1; ACCA
UniProt ID: (Human) Q13085
Entrez Gene ID: (Human) 31
tissue homeostasis
acetyl-CoA metabolic process
fatty acid biosynthetic process
biotin metabolic process
carnitine shuttle
positive regulation of cellular metabolic process
long-chain fatty-acyl-CoA biosynthetic process
multicellular organismal protein metabolic process
protein homotetramerization
lipid homeostasis
cellular response to prostaglandin E stimulus
malonyl-CoA biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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