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Antibody detects endogenous levels of total ACP5.
Tartrate-resistant acid phosphatase (TRAP) is a basic iron-binding protein with high activity towards phosphoproteins, ATP and 4-nitrophenyl phosphatase. It is detected in human alveolar macrophages, osteoclasts, spleen and liver. Its expression is increased in spleen and monocytes of patients with Gaucher's disease; spleenocytes and circulating leukocytes of patients with hairy cell leukemia; spleen of patients with Hodgkin's lymphoma and in the sera of patients undergoing active bone turnover.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: acid phosphatase type V; human purple acid phosphatase; Tartrate-resistant acid ATPase; tartrate-resistant acid phosphatase 5a; tartrate-resistant acid phosphatase 5b; Tartrate-resistant acid phosphatase type 5; TR-AP; TRAPase; TrATPase; Type 5 acid phosphatase
Gene Aliases: ACP5; HPAP; T5ap; TRACP; TRACP5a; TRACP5b; TRAP; TrATPase; TTRRAP
UniProt ID: (Human) P13686, (Rat) P29288, (Mouse) Q05117
Entrez Gene ID: (Human) 54, (Rat) 25732, (Mouse) 11433
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