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            • Primary Antibodies ›
            • ADAMTS10 Antibodies

            Invitrogen

            ADAMTS10 Polyclonal Antibody

            View all (6) ADAMTS10 antibodies
            Datasheet
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            Catalog # PA5-75824
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            Price (USD)
            502.00
            100 µL
             
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            Cite ADAMTS10 Polyclonal Antibody

            • Antibody Testing Data (2)
            Application
            ADAMTS10 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Group 53 Created with Sketch.

            FIGURE: 1 / 2

            ADAMTS10 Antibody (PA5-75824) in IHC (P)

            Immunohistochemistry analysis of ADAMTS10 in paraffin-embedded human lung carcinoma tissue (cytoplasmic staining) and negative control (right, with PBS only). Samples were incubated with ADAMTS10 polyclonal antibody (Product # PA5-75824) at a dilution of 1:50, followed by goat Anti-Rabbit IgG-biotin and avidin peroxidase.
            View Product

            ADAMTS10 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ADAMTS10 Antibody in Western Blot (WB)

            Product Details

            PA5-75824

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:500-1:1,000
            -

            Immunohistochemistry (Paraffin) (IHC (P))

            1:50-1:200
            -
            Product Specifications

            Species Reactivity

            Human, Mouse, Rat

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Synthetic peptide corresponding to residues in Human ADAMTS10.

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            1 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            PBS, pH 7.3

            Contains

            0.02% sodium azide

            Storage conditions

            Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2719552

            Product Specific Information

            The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

            Target Information

            ADAMTS (a disintegrin and metalloproteinase domain with Thrombospondin type-1 modules) is a family of zinc-dependent proteases that are implicated in a variety of normal and pathological conditions, including arthritis and cancer (1-3). Embryogenesis, morphological growth changes, inflammation, tumor invasion and metastasis involve the breakdown and remodeling of the extracellular matrix. This degradation is due to the family of enzymes known as the matrix metalloproteinases (MMPs), which are related to ADAMTS subtypes. ADAMTS protein family members contain an amino-terminal propeptide domain, a metalloproteinase domain, a disintegrin-like domain and a carboxy-terminus that contains a varying number of thrombospondin type-1 (TSP-1) motifs (1-3). ADAMTS genes are primarily expressed in fetal tissues, including the lung, kidney and liver (1-3). The human ADAMTS10 gene maps to chromosome 19p13.3 (4). The human ADAMTS19 gene maps to chromosome 5q31 (1,5).

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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            Cite this product

            Bioinformatics

            Protein Aliases: a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 10; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 10; a disintegrin-like and metalloprotease with thrombospondin type 1 motif, 10; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif, 10; ADAM-TS 10; ADAMs; metalloendopeptidases; zinc metalloendopeptidase

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            Gene Aliases: 9430006O18; ADAM-TS10; ADAMTS-10; ADAMTS10; AW045948; WMS; WMS1; Znmp

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            UniProt ID: (Human) Q9H324, (Mouse) P58459

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            Entrez Gene ID: (Human) 81794, (Mouse) 224697, (Rat) 314655

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            Function(s)

            molecular_function metalloendopeptidase activity protein binding zinc ion binding peptidase activity metallopeptidase activity hydrolase activity metal ion binding metalloprotease

            Process(es)

            proteolysis biological_process
            It has to be done as per old AB suggested Products section.
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