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Product Details
MA5-33369
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
1B2-8-14
Conjugate
Form
Liquid
Concentration
100 µg/mL
Purification
Protein G
Storage buffer
PBS with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
4° C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2815507
Product Specific Information
Product is supplied at 1 mL (100 µL/mL). This antibody recognizes the spacer domain and reacts with molecular species of 55 kDa or a doublet of 55 kDa and 60 kDa (glycosylated form). Note that proteolysis of Punctin-1 has been described and additional smaller bands may also be obtained.
Western blotting applications the antibody works better in non-reducing than reducing conditions although it will also recognize the reduced antigen at correspondingly higher concentrations.
Target Information
Punctin (ADAMTSL-1) is a secreted molecule, expressed in adult skeletal muscle, resembling members of the ADAMTS family of proteases, containing four thrombospondin type I repeats. Human punctin cleaves aggrecan and is thereby classified as an aggrecanase. Like the ADAMTS proteases, each domain in punctin has an even number of cysteine residues suggesting that each domain may have internal disulfide bonds and that punctin consists of a series of independently folded and disulfide-bonded domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: a disintegrin and metalloproteinase; ADAM; ADAM-TS related protein 1; ADAMs; ADAMTS-like 1; ADAMTS-like protein 1; ADAMTSL-1; DKFZp686L03130; FLJ35283; FLJ41032; FLJ46891; metalloendopeptidases; MGC118803; MGC118805; MGC40193; Punctin-1; RP11-220B22.2
Gene Aliases: ADAMTSL-1; ADAMTSL1; ADAMTSR1; C9orf94; PUNCTIN; UNQ528/PRO1071
UniProt ID: (Human) Q8N6G6
Entrez Gene ID: (Human) 92949
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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