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Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AC8; adenylate cyclase 8 (brain); Adenylate cyclase type 8; Adenylate cyclase type VIII; Adenylyl cyclase 8; adenylyl cyclase-8, brain; ATP pyrophosphate-lyase 8; Ca(2+)/calmodulin-activated adenylyl cyclase; epididymis secretory sperm binding protein Li 172mP; HEL-S-172mP; type VIII adenylyl cyclase
Gene Aliases: AC8; ADCY3; ADCY8; AW060868; HBAC1
UniProt ID: (Human) P40145, (Rat) P40146, (Mouse) P97490
Entrez Gene ID: (Human) 114, (Rat) 29241, (Mouse) 11514
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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