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Proteintech

AGXT Recombinant Rabbit Monoclonal Antibody (240305E7)

View all (12) AGXT antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (5)

Application

AGXT Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 5

AGXT Antibody (83385-6-RR) in ICC/IF

Immunofluorescent analysis of (4% PFA) fixed HeLa cells using AGXT antibody (83385-6-RR, Clone: 240305E7) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG (H+L) (SA00013-2), CL594-Phalloidin (red).

AGXT Antibody in Surface plasmon resonance (SPR)

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Product Details

83385-6-RR

Applications

Tested Dilution

Publications

Western Blot (WB)

1:5,000-1:50,000

Immunocytochemistry (ICC/IF)

1:50-1:500

Flow Cytometry (Flow)

0.25 µg/10^6 cells in a 100 µL suspension

ELISA (ELISA)

Assay-dependent

Surface plasmon resonance (SPR)

Assay-dependent

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293F

Class

Recombinant Monoclonal

Type

Antibody

Clone

240305E7

Immunogen

AGXT fusion protein Ag18062

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Product Specific Information

Immunogen sequence: MASHKLLVTP PKALLKPLSI PNQLLLGPGP SNLPPRIMAA GGLQMIGSMS KDMYQIMDEI KEGIQYVFQT RNPLTLVISG SGHCALEAAL VNVLEPGDSF LVGANGIWGQ RAVDIGERIG ARVHPMTKDP GGHYTLQEVE EGLAQHKPVL LFLTHGESST GVLQPLDGFG ELCHRYKCLL LVDSVASLGG TPLYMDRQGI DILYSGSQKA LNAPPGTSLI SFSDKAKKKM YSRKTKPFSF YLDIKWLANF WGCDDQPRMY HHTIPVISLY SLRESLALIA EQGLENSWRQ HREAAAYLHG RLQALGLQLF VKDPALRLPT VTTVAVPAGY DWRDIVSYVI DHFDIEIMGG LGPSTGKVLR IGLLGCNATR ENVDRVTEAL RAALQHCPKK KL

Target Information

This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: AGT; Alanine--glyoxylate aminotransferase; hepatic peroxisomal alanine:glyoxylate aminotransferase; L-alanine: glyoxylate aminotransferase 1; Serine--pyruvate aminotransferase; serine-pyruvate aminotransferase; serine:pyruvate aminotransferase; SPT

Gene Aliases: AGT; AGT1; AGXT; AGXT1; PH1; SPAT; SPT; TLH6

UniProt ID: (Human) P21549

Entrez Gene ID: (Human) 189

Function(s)

serine-pyruvate transaminase activity receptor binding protein binding alanine-glyoxylate transaminase activity transaminase activity amino acid binding pyridoxal phosphate binding protein homodimerization activity protein self-association transaminase

Process(es)

Notch signaling pathway glyoxylate catabolic process proteasomal protein catabolic process glycine biosynthetic process, by transamination of glyoxylate L-cysteine catabolic process L-alanine catabolic process pyruvate biosynthetic process glyoxylate metabolic process oxalic acid secretion response to glucocorticoid response to cAMP

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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