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AJAP1, Adherens Junction Associated Protein 1, plays a key role in cell adhesion and cell migration. It is a transmembrane protein found on the basolateral surface of epithelium and expressed by multiple types of epithelium. AJAP1 interacts with E-Cadherin and appears to promote the internalization of E-Cadherin upon growth factor stimulation. This facilitates the dissolution of adherens junctions with an increase in cell motility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: adherens junction associated protein 1; Adherens junction-associated protein 1; likely ortholog of H. sapiens transmembrane protein SHREW1; Membrane protein shrew-1; Neumo48; RP3426F10.1; transmembrane protein SHREW1
Gene Aliases: AJAP1; Gm573; MOT8; Neumo48; SHREW-1; SHREW1
UniProt ID: (Human) Q9UKB5, (Rat) Q4W8E7, (Mouse) A2ALI5
Entrez Gene ID: (Human) 55966, (Rat) 687031, (Mouse) 230959
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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