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Product Details
PA5-52672
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ALKBH3
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2637866
Product Specific Information
Immunogen sequence: WAAPVKSQAI AQPATTAKSH LHQKPGQTWK NKEHHLSDRE FVFKEPQQVV RRAPEPRVID REGVYEISLS PTGVSRVCLY PGFVDVKEAD WILEQLCQDV PWKQRTGIRE DITYQQPRLT AWYGEL
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 79%.
Target Information
Dioxygenase that repairs alkylated DNA containing 1- methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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