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            • Primary Antibodies ›
            • GFER Antibodies

            Proteintech

            ALR Polyclonal Antibody

            36 References
            View all (6) GFER antibodies
            Datasheet
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            Questions & Answers
            Datasheet
            Protocols
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            Cite ALR Polyclonal Antibody

            • Antibody Testing Data (14)
            Application
            ALR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Group 53 Created with Sketch.

            FIGURE: 1 / 14

            ALR Antibody (11293-1-AP) in IHC (P)

            Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using (Product # 11293-1-AP) (ALR antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).
            View Product

            ALR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ALR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ALR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ALR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ALR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ALR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ALR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ALR Antibody in Western Blot (WB)
            ALR Antibody in Western Blot (WB)
            ALR Antibody in Western Blot (WB)
            ALR Antibody in Western Blot (WB)
            ALR Antibody in Western Blot (WB)
            ALR Antibody in Western Blot (WB)
            ALR Antibody in Immunoprecipitation (IP)

            Product Details

            11293-1-AP

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:500-1:1,000
            View 20 publications 20 publications

            Immunohistochemistry (IHC)

            -
            View 3 publications 3 publications

            Immunohistochemistry (Paraffin) (IHC (P))

            1:20-1:200
            -

            Immunocytochemistry (ICC/IF)

            -
            View 7 publications 7 publications

            Flow Cytometry (Flow)

            Assay-dependent
            View 1 publication 1 publication

            Immunoprecipitation (IP)

            0.5-4.0 µg
            -

            Miscellaneous PubMed (Misc)

            -
            View 2 publications 2 publications

            Not applicable (N/A)

            -
            View 3 publications 3 publications
            Product Specifications

            Species Reactivity

            Human, Mouse, Rat

            Published species

            Human, Mouse

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            ALR Fusion Protein Ag1840 (1-125 aa encoded by BC028348)
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.36 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            PBS, pH 7.3, with 50% glycerol

            Contains

            0.02% sodium azide

            Storage conditions

            -20°C

            Shipping conditions

            Wet ice (domestic); Dry ice (international)

            Product Specific Information

            Immunogen sequence: MRTQQKRDT KFREDCPPDR EELGRHSWAV LHTLAAYYPD LPTPEQQQDM AQFIHLFSKF YPCEECAEDL RKRLCRNHPD TRTRACFTQW LCHLHNEVNR KLGKPDFDCS KVDERWRDGW KDGSCD (1-125 aa encoded by B C028348)

            Target Information

            Isoform 1: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re- oxidized by donating electrons to cytochrome c or molecular oxygen.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            Bioinformatics

            Protein Aliases: Augmenter of liver regeneration; ERV1 homolog; erv1-like growth factor; FAD-linked sulfhydryl oxidase ALR; growth factor, erv1 homolog; growth factor, erv1-like (augmenter of liver regeneration); hepatic regenerative stimulation substance; Hepatopoietin; hepatopoietin protein; hERV1

            View more View less

            Gene Aliases: ALR; ERV1; GFER; HERV1; HPO; HPO1; HPO2; HSS; MNCb-0663

            View more View less

            UniProt ID: (Human) P55789, (Rat) Q63042, (Mouse) P56213

            View more View less

            Entrez Gene ID: (Human) 2671, (Rat) 27100, (Mouse) 11692

            View more View less

            Function(s)

            protein binding growth factor activity protein disulfide oxidoreductase activity thiol oxidase activity flavin adenine dinucleotide binding flavin-linked sulfhydryl oxidase activity oxidoreductase activity oxidase oxidoreductase metabolite interconversion enzyme

            Process(es)

            oxidation-reduction process response to lipopolysaccharide negative regulation of apoptotic process negative regulation of natural killer cell mediated cytotoxicity cellular response to lipopolysaccharide cellular response to tumor necrosis factor cellular response to actinomycin D cellular response to toxic substance liver regeneration negative regulation of oxidative stress-induced neuron death positive regulation of DNA biosynthetic process
            It has to be done as per old AB suggested Products section.
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