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FIGURE: 1 / 2
ALS2CR11 has 2 isoforms of the human protein that are produced by alternative splicing. An autosomal recessive form of juvenile amyotrophic lateral sclerosis was originally mapped to a region of chromosome 2 that includes this gene. The encoded protein contains a calcium-dependent membrane targeting C2 domain. This domain is often found in proteins that are involved in membrane trafficking and signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein; C2 calcium-dependent domain-containing protein 6; Cation channel sperm-associated targeting subunit tau; CatSper-tau; testicular tissue protein Li 16
Gene Aliases: ALS2CR11; C2CD6; CATSPERT
UniProt ID: (Human) Q53TS8
Entrez Gene ID: (Human) 151254
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