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This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes.
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Protein Aliases: AMBP protein; bikunin; complex-forming glycoprotein heterogeneous in charge; growth-inhibiting protein 19; inter-alpha-trypsin inhibitor light chain; Protein AMBP; Protein HC; Protein Protein HC; trypstatin; uristatin; uronic-acid-rich protein
Gene Aliases: A1M; AMBP; EDC1; HCP; HI30; IATIL; ITI; ITIL; ITILC; UTI
UniProt ID: (Human) P02760
Entrez Gene ID: (Human) 259
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