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Immunogen sequence: VSKLWVPNTD FDVAANWSQN RTPCAGGAVE FPADKMVSVL VQEGHAVSDM LLPLDGELVL ASGAGFGVSD VGSHLDCGAG EPAVFRDSDR FSWHDPHLWR SGDEAPGLFF VDAERVPCRH DDVFFPPSAS FRVGLGPGAS PVRVRSISAL GRTFTRDEDL AVFLASRAGR LRFHGPGALS VGPED
The protein encoded by this gene is a type I transmembrane protein. It is thought to modulate bone morphogenetic protein (BMP) receptor function by serving as an accessory or coreceptor, and thus facilitates or hinders BMP binding. It is known that the mouse AMN gene is expressed in the extraembryonic visceral endoderm layer during gastrulation, but it is found to be mutated in amnionless mouse. The encoded protein has sequence similarity to short gastrulation (Sog) and procollagen IIA proteins in Drosophila.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: amnionless homolog; Protein amnionless; visceral endoderm-specific type 1 transmembrane protein
Gene Aliases: AMN; amnionless; PRO1028; UNQ513/PRO1028
UniProt ID: (Human) Q9BXJ7
Entrez Gene ID: (Human) 81693
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