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Invitrogen
AMPK gamma-2 Polyclonal Antibody
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Application
FIGURE: 1 / 3
AMPK gamma-2 Antibody (PA5-22331) in IHC (P)
AMPK gamma-2 Polyclonal Antibody detects PRKAG2 protein at nucleus and cytosol human on hepatoma by immunohistochemical analysis. Sample: Paraffin-embedded hepatoma. AMPK gamma-2 Polyclonal Antibody (Product # PA5-22331) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Product Details
PA5-22331
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human AMPK gamma 2. The exact sequence is proprietary.
Conjugate
Unconjugated
Form
Liquid
Concentration
0.96 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11152969
Product Specific Information
Recommended positive controls: HepG2, Mouse brain.
Predicted reactivity: Mouse (98%), Rat (97%), Chicken (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family and encodes a protein with four cystathionine beta-synthase domains. Mutations in this gene have been associated with ventricular pre-excitation (Wolff-Parkinson-White syndrome), progressive conduction system disease and cardiac hypertrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5'-AMP-activated protein kinase subunit gamma-2; 5-AMP-activated protein kinase, gamma-2 subunit; ampk gamma; AMPK gamma-2 chain; AMPK gamma2; AMPK subunit gamma-2; H91620p; OTTHUMP00000211956; protein kinase, AMP-activated, gamma 2 non-catalytic subunit
Gene Aliases: 2410051C13Rik; AAKG; AAKG2; AI854673; CMH6; H91620p; PRKAG2; WPWS
UniProt ID: (Human) Q9NUZ9, (Mouse) Q91WG5
Entrez Gene ID: (Human) 51422, (Mouse) 108099
Performance Guarantee
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