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            • Primary Antibodies ›
            • Ankyrin G Antibodies

            Proteintech

            ANK3 Polyclonal Antibody

            View all (25) Ankyrin G antibodies
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            Cite ANK3 Polyclonal Antibody

            • Antibody Testing Data (8)
            Application
            ANK3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Group 53 Created with Sketch.

            FIGURE: 1 / 8

            ANK3 Antibody (27766-1-AP) in IHC (P)

            Immunohistochemistry of paraffin-embedded mouse kidney tissue slide using 27766-1-AP (ANK3 antibody) at dilution of 1:200 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).
            View Product

            ANK3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ANK3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ANK3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ANK3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ANK3 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
            ANK3 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
            ANK3 Antibody in Western Blot (WB)
            ANK3 Antibody in Western Blot (WB)

            Product Details

            27766-1-AP

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:500-1:1,000
            -

            Immunohistochemistry (Paraffin) (IHC (P))

            1:50-1:500
            -

            Immunohistochemistry (PFA fixed) (IHC (PFA))

            1:50-1:500
            -

            Immunocytochemistry (ICC/IF)

            1:50-1:500
            -
            Product Specifications

            Species Reactivity

            Human, Mouse

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            ANK3 Fusion Protein Ag26948 (3668-3870 aa encoded by NM_001149)

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.3 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            PBS, pH 7.3, with 50% glycerol

            Contains

            0.02% sodium azide

            Storage conditions

            -20°C

            Shipping conditions

            Wet ice (domestic); Dry ice (international)

            Product Specific Information

            Immunogen sequence: METNLERNV ETPTVEPNPS IPTSGECQEG TSSSGSLEKS AAATNTSKVD PKLRTPIKMG ISASTMTMKK EGPGEITDKI EAVMTSCQGL ENETITMISN TANSQMGVRP HEKHDFQKDN FNNNNNLDSS TIQTDNIMSN IVLTEHSAPT CTTEKDNPVK VSSGKKTGVL QGHCVRDKQK VLGEQQKTKE LIGIRQKSKL PIKAT (3668-3870 aa encoded by NM_001149)

            Target Information

            Ankyrin-G is found in several tissues including brain where, due to tissue-specific RNA processing, it is expressed as two different isoforms, localized to axon initial segments and nodes of Ranvier. Ankyrin-G is also found at sites of epithelial cell-cell contact and in the intracellular membranes of some cells. Ankyrin-G isoforms contain a unique stretch of sequence highly enriched in serine and threonine residues immediately following a globular head domain. Ankyrin-G is thought to participate in the maintenance and targeting of ion channels and cell adhesion molecules to the nodes of Ranvier and to axon initial segments.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: ANK-3; Ankyrin-3; Ankyrin-G; brain-specific ankyrin-G

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            Gene Aliases: 2900054D09Rik; AI314020; Ank-3; ANK3; AnkG; Ankyrin-3; ANKYRIN-G; MRT37

            View more View less

            UniProt ID: (Human) Q12955, (Mouse) G5E8K5

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            Entrez Gene ID: (Human) 288, (Mouse) 11735

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            Function(s)

            structural constituent of cytoskeleton protein binding cytoskeletal protein binding cytoskeletal adaptor activity spectrin binding protein binding, bridging ion channel binding cadherin binding scaffold/adaptor protein

            Process(es)

            mitotic cytokinesis ER to Golgi vesicle-mediated transport plasma membrane organization cytoskeletal anchoring at plasma membrane signal transduction axonogenesis axon guidance neuromuscular junction development positive regulation of gene expression positive regulation of cell communication by electrical coupling positive regulation of sodium ion transport magnesium ion homeostasis neuronal action potential positive regulation of homotypic cell-cell adhesion Golgi to plasma membrane protein transport regulation of potassium ion transport establishment of protein localization positive regulation of membrane potential cellular response to magnesium ion membrane assembly protein localization to plasma membrane maintenance of protein location in plasma membrane protein targeting to plasma membrane positive regulation of protein targeting to membrane positive regulation of membrane depolarization during cardiac muscle cell action potential negative regulation of delayed rectifier potassium channel activity positive regulation of sodium ion transmembrane transporter activity positive regulation of cation channel activity positive regulation of action potential synapse organization
            It has to be done as per old AB suggested Products section.
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