Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Recommended positive controls: A431, Raji.
Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (92%), Xenopus laevis (96%), Chicken (99%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as the small subunit of this complex and is a member of the adaptin protein family. Transcript variants utilizing alternative polyadenylation signals exist for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: adapter-related protein complex 1 sigma-1B subunit; adaptor protein complex AP-1 sigma-1B subunit; Adaptor protein complex AP-1 subunit sigma-1B; adaptor-related protein complex 1 sigma 2 subunit; Adaptor-related protein complex 1 subunit sigma-1B; adaptor-related protein complex 1, sigma 2 subunit; AP-1 complex subunit sigma-2; clathrin adaptor complex AP1 sigma 1B subunit; Clathrin assembly protein complex 1 sigma-1B small chain; Golgi adaptor HA1/AP1 adaptin sigma-1B subunit; MGC:1902; Sigma 1B subunit of AP-1 clathrin; Sigma-adaptin 1B; Sigma1B-adaptin
Gene Aliases: AP1S2; DC22; MRX59; MRXS21; MRXS5; MRXSF; PGS; SIGMA1B
UniProt ID: (Human) P56377
Entrez Gene ID: (Human) 8905
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