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Peptide Sequence: MQFMLLFSRQ GKLRLQKWYV PLSDKEKKKI TRELVQTVLA RKPKMCSFLE WRDLKIVYKR YASLYFCCAI EDQDNELITL EIIHRYVELL DKYFGSVCEL DIIFNFEKAY FILDEFLLGG EVQETSKKNV LKAIEQADLL QEEAETPRSV LEEIGLT
Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as the small subunit of this complex and is a member of the adaptin protein family. Transcript variants utilizing alternative polyadenylation signals exist for this gene.
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Protein Aliases: adapter-related protein complex 1 sigma-1B subunit; adaptor protein complex AP-1 sigma-1B subunit; Adaptor protein complex AP-1 subunit sigma-1B; adaptor-related protein complex 1 sigma 2 subunit; Adaptor-related protein complex 1 subunit sigma-1B; adaptor-related protein complex 1, sigma 2 subunit; AP-1 complex subunit sigma-2; clathrin adaptor complex AP1 sigma 1B subunit; Clathrin assembly protein complex 1 sigma-1B small chain; Golgi adaptor HA1/AP1 adaptin sigma-1B subunit; MGC:1902; Sigma 1B subunit of AP-1 clathrin; Sigma-adaptin 1B; Sigma1B-adaptin
Gene Aliases: AP1S2; DC22; MRX59; MRXS21; MRXS5; MRXSF; PGS; SIGMA1B
UniProt ID: (Human) P56377
Entrez Gene ID: (Human) 8905
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