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Invitrogen

AP2 gamma Polyclonal Antibody

Name: AP2 gamma Polyclonal Antibody
Brand: Invitrogen
SKU: PA517330
Price: 540.0 USD

Advanced Verification

1 Published Figure

2 References

View all (26) AP2 gamma antibodies

Datasheet

Protocols

Questions & Answers

Catalog # PA5-17330

Price (USD)

540.00

100 µL

Estimated availability date: 23-Jun-2025

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Datasheet

Protocols

Questions & Answers

Application

AP2 gamma Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 7

AP2 gamma Antibody (PA5-17330) in ICC/IF

Immunofluorescence analysis of AP2Gamma was performed using 70% confluent log phase MCF-7 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with AP2 gamma Polyclonal Antibody (Product # PA5-17330) at 5 µg/mL in 0.1% BSA, incubated at 4 degree Celsius overnig... View More

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Product Details

PA5-17330

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

Immunocytochemistry (ICC/IF)

1:400

View 2 publications 2 publications

ChIP assay (ChIP)

5 µL/10^6 cells

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to the sequence of human AP-2 gamma

Conjugate

Unconjugated

Form

Liquid

Concentration

21 µg/mL

Purification

Antigen affinity chromatography

Storage buffer

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

Contains

no preservative

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_10989511

Product Specific Information

It is not recommended to aliquot this antibody.

Target Information

The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Fragile Gene WWOX Guides TFAP2A/TFAP2C-Dependent Actions Against Tumor Progression in Grade II Bladder Cancer.

Frontiers in oncology

Kołat D,Kałuzińska Ż,Płuciennik E

Thu Apr 21 00:00:00 UTC 2022

Fragile Gene WWOX Guides TFAP2A/TFAP2C-Dependent Actions Against Tumor Progression in Grade II Bladder Cancer.

Frontiers in oncology

Kołat D,Kałuzińska Ż,Płuciennik E

Thu Apr 21 00:00:00 UTC 2022

WWOX Loses the Ability to Regulate Oncogenic AP-2γ and Synergizes with Tumor Suppressor AP-2α in High-Grade Bladder Cancer.

Cancers

Kołat D,Kałuzińska Ż,Bednarek AK,Płuciennik E

Sat Jun 12 00:00:00 UTC 2021

Bioinformatics

Protein Aliases: Activating enhancer-binding protein 2 gamma; AP2-gamma; estrogen receptor factor 1; Transcription factor AP-2 gamma; transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma); transcription factor AP-2 gamma (activating enhancer-binding protein 2 gamma); Transcription factor ERF-1

Gene Aliases: AP2-GAMMA; ERF1; hAP-2g; TFAP2C; TFAP2G

UniProt ID: (Human) Q92754

Entrez Gene ID: (Human) 7022

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding core promoter binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding protein dimerization activity general transcription factor

Process(es)

negative regulation of transcription from RNA polymerase II promoter regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter cell-cell signaling male gonad development regulation of gene expression, epigenetic regulation of cell proliferation positive regulation of transcription from RNA polymerase II promoter

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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