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            • Primary Antibodies ›
            • Aprataxin Antibodies

            Proteintech

            APTX Polyclonal Antibody

            View all (12) Aprataxin antibodies
            Datasheet
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            Catalog # 26747-1-AP
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            Price (USD)
            492.00
            150 µL
             
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            Cite APTX Polyclonal Antibody

            • Antibody Testing Data (4)
            Application
            APTX Antibody in Immunocytochemistry (ICC/IF)
            Group 53 Created with Sketch.

            FIGURE: 1 / 4

            APTX Antibody (26747-1-AP) in ICC/IF

            Immunofluorescent analysis of ( 4% PFA) fixed HepG2 cells using 26747-1-AP (APTX antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).
            View Product

            APTX Antibody in Immunocytochemistry (ICC/IF)
            APTX Antibody in Western Blot (WB)
            APTX Antibody in Western Blot (WB)
            APTX Antibody in Western Blot (WB)

            Product Details

            26747-1-AP

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:500-1:2,000
            -

            Immunocytochemistry (ICC/IF)

            1:50-1:500
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            APTX Fusion Protein Ag24945 (1-164 aa encoded by BC104881)
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.33 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            PBS, pH 7.3, with 50% glycerol

            Contains

            0.02% sodium azide

            Storage conditions

            -20°C

            Shipping conditions

            Wet ice (domestic); Dry ice (international)

            Product Specific Information

            Immunogen sequence: MMRVCWLVR QDSRHQRIRL PHLEAVVIGR GPETKITDKK CSRQQVQLKA ECNKGYVKVK QVGVNPTSID SVVIGKDQEV KLQPGQVLHM VNELYPYIVE FEEEAKNPGL ETHRKRKRSG NSDSIERDAA QEAEAGTGLE PGSNSGQCSV PLKKGKDAPI KKESL (1-164 aa encoded by BC104881)

            Target Information

            This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: Aprataxin; FHA-HIT; Forkhead-associated domain histidine triad-like protein

            View more View less

            Gene Aliases: AOA; AOA1; APTX; AXA1; EAOH; EOAHA; FHA-HIT

            View more View less

            UniProt ID: (Human) Q7Z2E3

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            Entrez Gene ID: (Human) 54840

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            Function(s)

            chromatin binding damaged DNA binding double-stranded DNA binding double-stranded RNA binding protein binding phosphoglycolate phosphatase activity DNA 5'-adenosine monophosphate hydrolase activity metal ion binding protein N-terminus binding phosphoprotein binding damaged DNA-binding protein

            Process(es)

            single strand break repair DNA ligation cellular response to DNA damage stimulus dephosphorylation regulation of protein stability response to hydrogen peroxide nucleic acid phosphodiester bond hydrolysis
            It has to be done as per old AB suggested Products section.
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