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This gene encodes a member of the ALEX family of proteins and may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and two Armadillo (arm) repeats. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members, including ALEX2 and ALEX3, on the X chromosome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ARM protein lost in epithelial cancers on chromosome X 1; arm protein lost in epithelial cancers, X chromosome, 1; Armadillo repeat-containing X-linked protein 1; Protein ALEX1
Gene Aliases: AD032; ALEX1; ARMCX1; GASP7
UniProt ID: (Human) Q9P291
Entrez Gene ID: (Human) 51309
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