Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Predicted to react with Human and Rat samples.
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression by binding to the NGF-regulatory region of its mRNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ARPP-19; cAMP regulated phosphoprotein 19kDa; cAMP-regulated phosphoprotein 19; cAMP-regulated phosphoprotein 19kDa; cAMP-regulated phosphoprotein ARPP-19; cAMP-regulated phosphoprotein, 19kDa; cyclic AMP phosphoprotein, 19 kD; cyclic AMP phosphoprotein, 19 kDa; cyclic AMP phosphoprotein, 19kD
Gene Aliases: 19kDa; 2700024H10Rik; ARPP-16; ARPP-19; Arpp12; ARPP16; ARPP19; AW559096; ENSAL
UniProt ID: (Human) P56211, (Mouse) P56212, (Rat) Q712U5
Entrez Gene ID: (Human) 10776, (Mouse) 59046, (Rat) 60336
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