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Recommended positive controls: A549, HeLa, HepG2, HCT116.
Predicted reactivity: Mouse (92%), Rat (93%), Xenopus laevis (90%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
ATAD3A is a member of the AAA ATPase family, a family of proteins that catalyze ATP into ADP and are involved in several cellular functions such as cell-cycle regulation, protein proteolysis and transport. The AAA ATPase family is characterized by a highly conserved AAA motif containing Walker homology sequences and imparting ATPase activity. Mitochondrial membrane proteins ATAD3A/B contribute to the stabilization of nucleoids and may participate in the transformation pathway and the chemosensitivity of oligodendrogliomas. The gene encoding ATAD3A/B/C maps to human chromosome 1 and has been suggested to be an anti-apoptotic marker.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATPase family AAA domain-containing protein 3A; RP5-832C2.1
Gene Aliases: ATAD3A
UniProt ID: (Human) Q9NVI7
Entrez Gene ID: (Human) 55210
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