Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: KLMQQNPAG ELEGFQAQGH PPSLFPPKAK SNQPKSLEDL IFESLPENAS HKLEVRLVPV SFEDPEFKSS FSQSFSLYVK YQVAIHQDPP DECGKTEFTR FLCSSPLEAE TPPNGPDCGY GSFHQQYWLD GKIIAVGVID ILPNCVSSVY LYYDPDYSFL SLGVYSALRE IAFTRQLHEK TSQLSYYYMG FYIHSCPKMK YKGQYRPSDL LCPETYVWVP IEQCLPSLEN SKYCRFNQDP EAVDEDRSTE PDRLQVFHKR AIMPYGVYKK QQKDPSEEAA VLQYASLVGQ KCSERMLLFR N (219-518 aa encoded by BC022026)
Arginyl-tRNA-protein transferase (ATE1), also designated arginyltransferase 1, belongs to the R-transferase family of proteins. In order for a protein to be degraded via the ubiquitin pathway, arginylation of the protein is required. ATE1 plays an important role in this process, as it is important for the posttranslational conjugation of arginine to the N-terminal aspartate-, glutamate- and possibly cystine-contaning substrates. ATE1 is a 518 amino acid protein. Alternative splicing results in two distinct isoforms. ATE1, which is found as a monomer, can localize to the cytoplasm and/or the nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Arginine-tRNA--protein transferase 1; arginine-tRNA-protein transferase 1; Arginyl-tRNA--protein transferase 1; arginyl-tRNA-protein transferase; Arginyltransferase 1; R-transferase 1
Gene Aliases: AI225793; ATE1; AW547406
UniProt ID: (Human) O95260, (Mouse) Q9Z2A5
Entrez Gene ID: (Human) 11101, (Mouse) 11907, (Rat) 293526
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